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Behavioral Aspects of Pre-Exposure Prophylaxis (PrEP) Counseling for Intermittent Exposure
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Research Initiative
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CDC
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NIMH
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This agreement between the CDC''s National Center for HIV/AIDS, Viral Hepatitis, Sexually Transmitted Diseases, and Tuberculosis Prevention, and NIMH facilitates the conduct of research for the prevention and treatment of HIV/AIDS.Y1-MH-0315
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Behavioral Economics for Nudging the Implementation of Comparative Effectiveness Research: Pilot Research (RC4)
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Research Initiative
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AHRQ
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NIA, NCI, NIDA, NIMH, NINDS, NINR
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NIH and AHRQ under the American Recovery & Reinvestment Act of 2009 made available funding for applications to study how the principles of behavioral economics could be used to enhance the results of comparative effectiveness research among health care providers in their practice. This NIH Funding Opportunity Announcement (FOA), supported by funds provided to the NIH and AHRQ under the American Recovery & Reinvestment Act of 2009 (“Recovery Act” or “ARRA”), Public Law 111-5, invites applications to study how the principles of behavioral economics could be used to enhance the uptake of the results of comparative effectiveness research (CER) among health care providers in their practice. (For this FOA, applications should be thought of as large pilot or preliminary studies rather than definitive trials.) This funding opportunity seeks applications that will investigate whether the principles of behavioral economics could be used to enhance the uptake of the results CER among health care providers and also enhance the maintenance of such treatments in patient populations. Research to foster the uptake of CER is seen to be necessary given the surprisingly modest behavioral response of health care providers and health care systems to information concerning treatments or procedures judged to be superior in CER trials. An additional possible benefit is that some behavioral economic interventions to promote the uptake of CER could be far more cost effective than other approaches including some pay for performance schemes (P4P). For the purposes of this FOA, the definition of comparative effectiveness research will adhere to that adopted by the Federal Coordinating Council given at http://www.hhs.gov/recovery/programs/cer/cerannualrpt.pdf. Behavioral economics refers to the interdisciplinary efforts involving cognitive and social psychologists, decision scientists, and other social scientists together with economists to model economic decision-making and consequent actions. The approach is inclusive, since at its heart it tries to take into account what is known about how people actually make behavioral decisions rather than relying on the assumption that economic agents are fundamentally rational in the sense of expected utility theory (see, e.g.,Kahneman and Tversky’s (1979) work on Prospect Theory and Kahneman’s (2003) Nobel lecture). It is hoped that this line of research will lead to significantly greater understanding of the adoption of CER by health care providers and therefore enhance the quality of the nation’s health. Mechanism of Support. This FOA will use the ARRA-specific NIH mechanism RC4.
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Behavioral Health and Electronic Health Records Subcommittee
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Committee, Work group, Advisory group, or Task Force
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AHRQ, CDC, CMS, HRSA, IHS, OS, SAMHSA
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OD, CC, NCI, NIAAA, NIDA, NIMH, NINR, NLM
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Behavioral health and Electronic Health Records subcommittee
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Behavioral Health and Primary Care Integration Subgroup of the Behavioral Health Coordinating Committee
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Committee, Work group, Advisory group, or Task Force
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CDC, CMS, HRSA, IHS, SAMHSA
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OD, NIMH
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Developing cross-cutting strategies for improving integration of behavioral health care and primary care
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Bench-to-Bedside (B2B) Program
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Research Initiative
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FDA
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CC, NCI, NCATS, NHGRI, NHLBI, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIGMS, NIMH, NIMHD, NINDS, NINR, OD
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An intramural Bench-to-Bedside Program was established in 1999 to integrate the work of basic and clinical scientists on the NIH campus and to foster collaborations across institutes. Since the program’s beginning, more than 500 principal and associate investigators have collaborated on 192 funded projects. The Clinical Center has coordinated the program for the past 13 years. Funding for the program is provided by ICs, the Food & Drug Administration, the NIH Office of Behavioral and Social Sciences Research, the Office of AIDS Research, the Office of Rare Diseases Research, the Office of Research on Women’s Health, the National Center on Minority Health and Health Disparities, the National Center for Research Resources and represents a total investment of approximately $44M. The program expanded in 2006 to encourage partnerships between intramural and extramural investigators.
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Best Pharmaceuticals for Children Act
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Research Initiative
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FDA
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NICHD, NHLBI, NIMH, OD
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The Best Pharmaceuticals for Children Act (BPCA) Program is a major activity for the Obstetric and Pediatric Pharmacology Branch (OPPB), a component of the Center for Research for Mothers and Children at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). OPPB is responsible for developing and supporting a comprehensive national research and training effort to increase the knowledge base for understanding how to appropriately treat disease during pregnancy, infancy, and childhood using pharmaceuticals that are appropriately tested within their target populations. NICHD activities related to BPCA are intended to improve pediatric drug therapeutics through preclinical and clinical testing that lead to drug labeling changes.
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Bilateral and Multilateral Health Activities
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Research Initiative
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OS
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NICHD, FIC, NCI, NHLBI, NIAAA, NIAID, NIDA, NIEHS, NIMH, OD
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The Bilateral and Multilateral Heath Activities agreement is coordinated by the Office of Global Health Affairs (OGHA). The primary function of Bilateral and Multilateral Activities is for overall policy and coordination of HHS'' International Health issues, social and family policy activities. A committee which consists of high-ranking policy level officials, scientists and international exchange visitors get together periodically and discuss international health and social issues and make policy recommendations/decisions.
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Bioresource Development, Validation Tools, and Integrating HTS Technology Standards in Probiotics
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Research Initiative
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CDC, HRSA, SAMHSA
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NCCAM, NCI, NCATS, NHLBI, NIAID, NIDDK, NIEHS, OD
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Collaborative efforts between the FDA/CBER and the NIH/NCCAM for substantiating health benefit claims for probiotics under INDs were placed in the framework of U01 Cooperative Agreements that began in 2008. The successful evaluation of the initiative has recently developed into an invitation to develop a Memorandum of Understanding to promote resource sharing and exchange of research expertise; development of demonstration project(s); and the initiation of trans-agency research initiatives focused on the integration of advanced molecular technologies that lead to harmonization standards and improved diagnostics for safety and substantiation of the health benefits of probiotic interventions. In 2011 a collaboration with FDA/CFSAN was initiated to expand the validation tool.
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Board of Scientific Counselors, CDC''s National Center for Injury Prevention and Control
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Committee, Work group, Advisory group, or Task Force
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CDC
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NIA
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A member of the NIA staff serves on the Board of Scientific Counselor''s for CDC''s National Center for Injury Prevention and Control. NIA''s staffer brings expertise in behavioral and social science research, research on older adults, and abuse and neglect.
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Body Mass and Mortality Relationships
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Research Initiative
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CDC
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NCI
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A study of the relationships between categories of body mass and mortality in the U.S. population.
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