| Collaborative on Healthy Parenting in Primary Care |
Public Education Campaign |
CDC, HRSA, SAMHSA |
|
The Collaborative on Healthy Parenting in Primary Care recognizes the accumulated evidence of the effectiveness of family-focused prevention programs that promote the physical and behavioral health and emotional well-being of children from before their birth through adolescence. Members of the Collaborative have united around an initiative to support the integration of effective programs that promote healthy parenting into primary care settings in order to achieve optimal health for children. |
| Combating Antibiotic Resistant Bacteria (CARB) |
Resource Development |
CDC, FDA |
NIAID, NLM |
The National Action Plan for Combating Antibiotic-Resistant Bacteria (CARB) is a multi-agency initiative to address urgent and serious drug-resistant threats that affect people in the U.S. and around the world. NLM contributes to several aspects of the plan to strengthen public health surveillance and data reporting while also advancing research to better understand environmental factors that contribute to antibiotic resistance. NLM's National Center for Biotechnology Information contributes to Sub-Objectives 2.1, 2.2, 2.4, 4.1, and 4.5 of the National Action Plan for Combating Antibiotic Resistant Bacteria https://obamawhitehouse.archives.gov/sites/default/files/docs/national_… |
| Commissioned Corps of the U.S. Public Health Service (USPHS) Oral Health Coordinating Committee (OHCC) |
Committee, Work group, Advisory group, or Task Force |
USPHS, ACF, ACL, AHRQ, ASPE, CDC, CMS, FDA, HRSA, OASH, SAMHSA |
NIDCR |
The United States Public Health Service (USPHS) Oral Health Coordinating Committee (OHCC), with representatives from HHS and other federal agencies, directs and coordinates a broad range of oral health policy, research, and programs within the USPHS, across federal agencies, and between the public and private sectors. The OHCC contributed to the HHS Oral Health Strategic Framework, 2014-2017 and the update is currently under publication review. |
| Community Preventive Services Task Force SDOH Coordination Team |
Committee, Work group, Advisory group, or Task Force |
CDC |
NIMHD |
The Community Preventive Services Task Force is conducting a systematic review on Paid Parental Leave |
| Comparison of Immunoassays Designed to Measure Immune Response to HPV Vaccination: The Serology Methods Study, Phase II (SMS-II) |
Research Initiative |
CDC |
NCI |
This work serves as an expansion to the original serology methods study (SMS I) that evaluated the validity and reproducibility of measures of the vaccine induced HPV16/18 antibody response by several HPV serologic assays. Now, with the investigation of single-dose regimens of the nonavalent HPV vaccine (9vHPV), it is necessary to expand this assessment to the additional seven genotypes included in the 9vHPV vaccine formulation. Further, as most of the assays evaluated in the first study were single-plex assays, performance characteristics for the HPV 16 and 18 antibody detection in multiplex assays testing of nine HPV types will be confirmed. The second phase of the methods work, the SMS II, continues to focus on single-dose HPV vaccine recipients as they have, on average, lower antibody levels compared to people who receive multi-dose regimens. |
| Complement Animal Research In Experimentation (Complement-ARIE) |
Research Initiative |
FDA, BARDA |
NCATS, NCCIH, NCI, NEI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIMH, NINDS, NLM, OD/DPCPSI/ODSS, OD/DPCPSI/ORIP, OD/DPCPSI/ORWH, OD/DPCPSI/OSC, OD/OSP |
The NIH Common Fund’s Complement Animal Research In Experimentation (Complement-ARIE) program will speed the development, standardization, validation, and use of human-based New Approach Methodologies (NAMs). NAMs are lab or computer-based research approaches intended to more accurately model human biology, and complement, or in some cases, replace traditional research models. The Complement-ARIE program will build upon ongoing efforts related to NAMs, while identifying opportunities for innovation and coordination. Complement-ARIE will significantly advance understanding of human health and disease by providing a range of ready and standardized biomedical research models. Developing these models will require expertise in disease research, personalized medicine, and in screening therapeutics for safety and effectiveness. |
| Computational Toxicology Analysis |
Committee, Work group, Advisory group, or Task Force |
FDA |
NIDA |
The Center for Drug Evaluation and Research at the Food and Drug Administration evaluates molecular structures for potential toxicities provided by NIDA using software platforms developed for this purpose. This interagency agreement stimulates the development of predictive software models that benefit drug discovery programs at both agencies. |
| Consumer Product Chemical Exposures in Pregnancy and Their Cumulative Impact on Disorders of Fetal Growth |
Research Initiative |
CDC |
NIEHS |
The purpose of this collaboration is to characterize exposure to organophosphate (OP) flame retardants and pesticides among pregnant women by measuring OP flame retardants and dialkyl phosphate metabolites (DAPs) in urine samples from 3 visits in pregnancy. We will examine associations between these markers and fetal growth as well as inflammation biomarkers. |
| Coordinated Sentinel Surveillance and Discovery Program for Emerging Human Pathogens |
Committee, Work group, Advisory group, or Task Force |
CDC |
OD/DPCPSI/OSC |
Ongoing detection and discovery (Khoj in Hindi) for surveillance of emerging and reemerging human pathogens are central to public health preparedness and outbreak detection and response at a regional, national, and international level. This surveillance is dependent on microbiological diagnoses from individual patients and, based on the type of infection, up to 60% of patients with serious infections may not have a pathogen identified even after extensive testing in the microbiology laboratory. There is no nationwide threat-agnostic surveillance system for emerging or reemerging human pathogens. Developing a coordinated sentinel surveillance system to apply advanced molecular methods (e.g., “shotgun metagenomics”) to clinical specimens from people with severe illness and who are negative by commercially available diagnostic assays would provide a foundation for systematic emerging pathogen discovery at an unprecedented scale, and significantly strengthen proactive preparedness and response capabilities. An interagency steering committee is in place to facilitate internal and external partnerships to conduct the project activities and establish a foundation of leadership and strategy for a national, coordinated sentinel surveillance system for emerging and reemerging human pathogens. Project activities that this steering committee will inform include: 1) developing the approach and scope of a targeted landscape analysis to identify existing activities and gaps in coordination; 2) establishing an information sharing mechanism to increase collaboration; 3) piloting receipt of specimens for external laboratories and analysis with shotgun metagenomic sequencing; and 4) examining the feasibility of accessing CDC resources to setup control panels. RTI International (RTI) will support advancing the Bio- Khoj project with CDC and the steering committee. |
| Coordinating Council on Access and Mobility |
Committee, Work group, Advisory group, or Task Force |
ACF, ACL, CDC, CMS, HRSA, IHS, OASH, SAMHSA |
NIA |
The Coordinating Council on Access and Mobility (CCAM) is a Federal interagency council that works to coordinate funding and provide expertise on human services transportation for three targeted populations: people with disabilities, older adults, and individuals of low income. |