|
SCOPE (Spinal Cord Injury Outcomes Endeavor)
|
Other
|
ACL
|
NICHD, NINDS
|
The Spinal Cord Outcomes Partnership Endeavor (SCOPE) aims to enhance the development of clinical trial and clinical practice protocols that will accurately validate therapeutic interventions for spinal cord injury (SCI) leading to the adoption of improved best practices.
|
|
SEARCH for Diabetes in Youth
|
Research Initiative
|
CDC
|
NIDDK
|
SEARCH is a multi-center study designed to characterize the epidemiology of both type 1 diabetes and type 2 diabetes in the population aged 20 years, along with the associated complications, quality of diabetes care, and quality of life of children and youth with diabetes. SEARCH aims also include 1) the development and validation of simple and low-cost case definitions and classifications of diabetes types in youth, 2) the establishment of a repository of biological specimens, and 3) systems to maintain contact with study participants to facilitate studies of childhood diabetes.
|
|
Seasonal Influenza Vaccine Improvement Group
|
Committee, Work group, Advisory group, or Task Force
|
CDC, FDA, OS
|
NIAID
|
The Influenza Vaccine Manufacturing Improvement Group aims to optimize donor strains, improve sterility assays, and develop alternative potency assays.
|
|
Senior Medical Advisor to Assistant Secretary for Preparedness and Response (ASPR)
|
Committee, Work group, Advisory group, or Task Force
|
OS
|
NCI, NIAID
|
A National Cancer Institute (NCI) staff member serves as Senior Medical Advisor to the Office of the Assistant Secretary for Preparedness and Response (ASPR). As such, NCI helps to develop plans for emergency and disaster responses and plays a role in responses operations as needed. A good number of the Operations plans and models that apply to all hazards have been developed from NCI science and knowledge.
|
|
Smokefree.gov
|
Resource Development
|
CDC, OS
|
NCI, OD/DPCPSI/OBSSR
|
Smokefree.gov is intended to help individuals quit smoking. Different people need different resources as they try to quit. The information and professional assistance available on this website can help to support both immediate and long-term needs as individuals become, and remain, a nonsmoker.
Smokefree.gov allows individuals to choose the help that best fits their needs. This collaboration also includes a number of smoking cessation text message programs throughout the world: China, Caribbean, Guam, American Samoa, and Samoa.
|
|
Society for Prevention Research Annual Meetings
|
Meeting/ Workshop
|
ACF, CDC
|
NIDA, NCI, NIAAA, NICHD, OD/DPCPSI/OBSSR, OD/DPCPSI/ODP
|
The Society for Prevention Research was formed in 1991 and has grown from a small group of researchers focused on drug and alcohol abuse prevention and mental health to become a leading scientific organization devoted to advancing prevention science, with 700+ members and a multidisciplinary prevention focus that emphasizes drug abuse, mental health, and HIV/AIDS prevention in addition to diverse, public health domains (e.g., obesity, violence, translational science). The annual meetings promote cross-fertilization of theory, methods, and intervention and provide an opportunity to enhance understanding of the underlying mechanisms of health-related issues with the goal of building the science of effective strategies, and for prevention and health promotion.
|
|
Somatic Cell Genome Editing
|
Research Initiative
|
FDA
|
OD/DPCPSI/OSC, NCATS, NCI, NHGRI, NHLBI, NIAID, NIAMS, NIDDK, NIMH, NINDS, OD/DPCPSI/ORIP
|
The Somatic Cell Genome Editing (SCGE) program aims to develop quality tools to perform effective and safe genome editing in human patients. These research tools will be made widely available to the research community to reduce the time and cost required to develop new therapies. A representative from FDA/CBER plays an advisory role for the program regarding regulatory issues. The program is also coordinating with the NIST Gene Editing consortium and the DARPA Safe Genes program and is exploring ideas for possible synergistic activities.
|
|
Specificity and Quality of Influenza-Specific Antibodies
|
Research Initiative
|
FDA
|
NIAID
|
This collaboration supports the evaluation of specificity and quality of influenza-specific antibodies in human subjects that have been vaccinated or naturally infected with influenza. Specific tasks include the construction of phage display libraries, production of recombinant proteins, development of surface plasmon resonance assays and the use of these technologies to measure antibody affinity maturation.
|
|
Standardized Machine-Readable Units of Measure
|
Committee, Work group, Advisory group, or Task Force
|
OS
|
NLM
|
Historically, the National Library of Medicine (NLM) has been at the nexus of standards needed to make clinical data flow to and from sources for clinical care, biomedical research, and epidemiologic databases. The big new research initiatives such as PCORI, Precision medicine, and the Cancer Moonshot depend heavily on efficient access to rich clinical data. A core problem of clinical data science is the prevalence of local and idiosyncratic coding systems used by individual care institutions. The major enabler of the use of big clinical Data is the standardization of the coding systems and formats (i.e. message standards) that clinical organizations use. On the coding system side, we have been developing, disseminating, and facilitating the adoption of universal standards, i.e., Unified Code for Units of Measure (UCUM) for units of measure so that clinical measures that different institutions report in different units of measure could be converted to a single unit of measure, which would simplify their use in care and research. We are working with NIST to promote the use of UCUM as a replacement for ISO-8000. We have also developed a web-based open source tool to enable the conversion of units of measure to standard machine-readable format using UCUM.
|
|
Standards for Genetic Testing Report
|
Research Initiative
|
AHRQ, CDC, OS
|
NLM, NHGRI
|
This activity aims to develop a standard reporting format for genetic variations using Logical Observation Identifiers Names and Codes (LOINC) and HL7, for electronic medical records health information exchange, and activities of the Office of the Secretary.
|