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Technical Working Group on National Security Risks Associated with the Applications Enabled by Advancements in Genome Editing and Synthesis Technologies and Other Related Enabling Technologies
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, OS
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OD/OSP, NIAID
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Discusses and evaluates current and emerging risks associated with applications enabled by advancements in genome editing and synthesis technologies and other related enabling technologies. These efforts are intended to support US government national security decision making, including the adjustment or development of policies and actions to address the national security risks associated with the applications of technologies under its purview.
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Technology Transfer Policy Board
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA
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OD/OIR/OTT, CC, CIT, NCATS, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NINDS, NINR, NLM, OD/OER, OD/OIR
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The purpose of the Public Health Service (PHS) Technology Transfer Policy Board (TTPB) is to serve as the principal advisory board to the National Institutes of Health (NIH) as lead agency in the PHS technology transfer program, the Centers for Disease Control and Prevention (CDC), and the Food and Drug Administration (FDA) in establishing PHS technology transfer policies and modifying existing policies, as applicable.
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Terminology Standards for Medicare Assessment Instruments
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Resource Development
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CMS
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NLM
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The National Library of Medicine (NLM) is working with the Centers for Medicare and Medicaid Services (CMS) to develop LOINC codes for all of the CMS Medicare assessment instruments.
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The Assistant Secretary for Preparedness and Response (ASPR)''s chemical, biological, radiological and nuclear defense team
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Committee, Work group, Advisory group, or Task Force
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OS
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NCI, NIAID
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The National Cancer Institute (NCI) and the National Institute of Allergy and Infectious Diseases (NIAID) participate in Assistant Secretary for Preparedness and Response (ASPR)''s chemical, biological, radiological and nuclear defense team. Both NCI and NIAID provide expertise on radiation topics and for the Biomedical Advanced Research and Development Authority (BARDA), within the Office of ASPR in the U.S.
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The Effect of Various Drugs on the Retina
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Research Initiative
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FDA
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NEI
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Using powerful in vivo imaging technology, it is possible to view the retina at the cellular level. This collaboration with the Food and Drug Administration (FDA) seeks to monitor changes to the retina for drugs that are known to cross the blood/retina barrier to better understand possible toxicity.
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The Environmental Determinants of Diabetes in the Young (TEDDY)
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Research Initiative
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CDC
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NIDDK, NIAID, NICHD, NIEHS
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This consortium is organizing international efforts to identify infectious agents, dietary factors, or other environmental factors that trigger type 1 diabetes in genetically susceptible people. The study enrolled over 8,000 newborns and is following them for 15 years to identify environmental triggers of type 1 diabetes.
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The Epidemiology of Burkitt Lymphoma in East-African Children and Minors (EMBLEM)
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Research Initiative
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CDC
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NCI
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The Epidemiology of Burkitt Lymphoma in East-African Children and Minors (EMBLEM) initiative provides a unique infrastructure to obtain valuable data and samples to study Burkitt’s lymphoma (BL) epidemiology. Study data will help characterize or investigate: (1) The association of malaria-resistance genes with endemic BL. (2) Host genetic polymorphisms associated with BL using genome-wide association methods. (3) The role of the Epstein-Barr virus (EBV) genetic variants in endemic BL. (4) The role of malaria immunology and phenotype of inflammation in BL. (5) The complexity of coinfection with different P. falciparum malaria genotypes in BL. (6) The interaction between helminthic parasites, HIV, malaria, and EBV in BL. (7) The immunohistochemistry and molecular pathology of BL. (8) The impact of malaria, helminthic parasites, and HIV on childhood BL.
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The Federal Tuberculosis Task Force
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Committee, Work group, Advisory group, or Task Force
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AHRQ, CDC, FDA, HRSA, IHS, OS
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NIAID, NICHD
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The Federal Tuberculosis (TB) Task Force is a coalition composed of the Federal agencies and organizations involved in US TB control efforts. Established in 1991, the Task Force facilitates coordination of activities between Federal agencies. It was created by the Director of the Centers for Disease Control and Prevention (CDC) to address the outbreaks of multidrug-resistant (MDR) TB occurring during the 1985-1992 surge in TB cases. The TB Task Force is co-chaired by CDC and NIAID.
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The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study
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Research Initiative
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CDC
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NIDDK, NHLBI
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GRADE is a randomized clinical trial of participants diagnosed with type 2 diabetes within the past 10 years who are already on metformin. Participants will be randomly assigned to 1 of 4 commonly-used glucose-lowering drugs (glimepiride, sitagliptin, liraglutide, and basal insulin glargine), plus metformin, and will be followed for up to 7 years. The goal of the GRADE Study is to determine which combination of two diabetes medications is best for achieving good glycemic control, has the fewest side effects, and is the most beneficial for overall health in long-term treatment for people with type 2 diabetes.
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The Golestan Cohort Study of Esophageal Cancer
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Research Initiative
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CDC
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NCI
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The National Cancer Institute (NCI) and the Centers for Disease Control and Prevention (CDC) are collaborating on a pilot study to measure nitrate in urine. The aim of the pilot is to determine if drinking water sources in high and low nitrate regions of Golestan province are associated with higher urinary nitrate concentrations (a biomarker of ingestion) after accounting for dietary intake.
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