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Action for Health in Diabetes (Look AHEAD)
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Research Initiative
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CDC, IHS
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NIDDK, NIA
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The Action for Health in Diabetes (Look AHEAD) is a randomized trial comparing the effects of Intensive Lifestyle Intervention (ILI) focused on weight loss achieved through healthy eating and increased physical activity versus a control condition of Diabetes Support and Education (DSE) in overweight and obese individuals with type 2 diabetes. The Look AHEAD Extension (LA-E) will examine whether ILI, provided for 10 years during mid-life, has enduring benefits that persist beyond the period of the intervention for older individuals with diabetes.
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Acute Flaccid Myelitis (AFM) Studies
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Research Initiative
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CDC
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NIAID, NICHD, NINDS
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This is a joint effort to find the cause of AFM by developing research initiatives as well as working group activities.
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Adjuvant Working Group
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Committee, Work group, Advisory group, or Task Force
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BARDA, FDA
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NIAID, NCI
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Staff from all National Institute of Allergy and Infectious Diseases (NIAID) Divisions, program staff from the Biomedical Advanced Research and Development Authority (BARDA), and regulatory staff from the Food and Drug Administration (FDA) exchange information about ongoing programs related to novel adjuvants for infectious disease vaccines, identify high priority research areas (and gap areas), and discuss ideas to accelerate progress in adjuvant research through better access to information and resources.
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Administrative Supplements on HIV Pre-Exposure Prophylaxis Implementation Science in CDC-Funded Public Health Demonstration Projects
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Research Initiative
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CDC
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NIMH
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The National Institute of Mental Health (NIMH), in collaboration with the Centers for Disease Control and Prevention (CDC), developed a request for applications to call for administrative supplements to currently funded NIH grants. These supplements would support implementation science research related to a CDC-funded public health initiative to reduce HIV infections in men who have sex with men (MSM) and transgender individuals through improved HIV pre-exposure prophylaxis (PrEP) planning, outreach, and delivery. Eight supplements were awarded. NIMH is continuing to work with the CDC to disseminate the findings from these supplements to relevant stakeholders.
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Adolescent Brain Cognitive Development (ABCD) Study
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Research Initiative
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CDC
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NIDA, NCI, NIAAA, NICHD, NIMH, NIMHD, NINDS, OD/DPCPSI/OBSSR
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The Adolescent Brain Cognitive Development (ABCD) project, a landmark longitudinal study of brain development and child health, will increase our understanding of how diverse experiences during adolescence interact with changing biology to influence brain, cognitive, and social/emotional development of youth. In partnership with area public and private schools, researchers at twenty-one research sites across the country will recruit 10,000 children at age 9-10 from diverse races and ethnicities, education and income levels, and living environments and follow them through their teens and into early adulthood. Throughout this period, researchers will assess each child’s physical and mental health, substance use, sleep patterns, genetics, childhood experiences, and cultural/environmental influences, as well as track brain and cognitive development with non-invasive magnetic resonance imaging scans at regular intervals. To enrich the value of the study, ABCD will release anonymized data annually to the research community in an open science model to allow scientists from all over the world to conduct analyses and pool resources to rapidly expand the types of scientific questions that can be answered. The actionable information coming out of this study will enable education, substance use prevention, and other health promotion policies to ensure the wellbeing and success of the Nation’s children.
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Adolescent Human Immunodeficiency Virus (HIV) Prevention and Treatment Implementation Science Alliance (AHISA)
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Committee, Work group, Advisory group, or Task Force
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CDC
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FIC, NIAID, NICHD, NIMH, OD/DPCPSI/OAR
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The Adolescent Human Immunodeficiency Vrus(HIV) Prevention and Treatment Implementation Science Alliance (AHISA) aims to enhance the effective use of evidence and help overcome implementation challenges related to prevention, screening, and treatment of HIV among adolescents (ages 15 to 24) in sub-Saharan Africa by catalyzing collaboration and communication among implementation scientists, program implementers, and policymakers. The goals of the Alliance are to: 1) provide a platform for cross-fertilization and exchange of ideas and information among implementation scientists and other stakeholders focusing on different aspects of HIV in adolescents; 2) enable the research to be better informed by programmatic challenges and questions; 3) inform policymakers of promising evidence and encourage use of the data in decision making; and 4) extend the reach and impact of implementation science related to adolescent HIV prevention and treatment.
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Adolescent Medication-Assisted Treatment and Opioids Committee
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Committee, Work group, Advisory group, or Task Force
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OS, SAMHSA
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NICHD, NIDA
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The goal of this committee is to provide federal agencies with a better understanding of adolescent medication-assisted treatment (MAT) policy, research, and practice and to inform future initiatives.
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Advanced Anticonvulsant System Interagency Product Team
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Committee, Work group, Advisory group, or Task Force
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FDA, OS
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NINDS
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The Advanced Anticonvulsant System Interagency Product Team is a Department of Defense-led effort to facilitate activities, both research and regulatory, related to the FDA approval of midazolam for use in treating nerve agent exposure.
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Advancing Early Psychosis Care in the United States: Innovations from the Field
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Meeting/ Workshop
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SAMHSA
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NIMH
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With the rapid expansion of evidence-based early psychosis care in the U.S., largely the result of the successful NIMH-funded Recovery After an Initial Schizophrenia Episode (RAISE) initiative, additional clinician training on early psychosis is needed. The National Institute of Mental Health (NIMH), in collaboration with the Substance Abuse and Mental Health Services Administration (SAMHSA), sponsored a meeting entitled, "Advancing Early Psychosis Care in the United States: Innovations from the Field," on October 7, 2018. The meeting was held as a pre-conference event in conjunction with the International Early Psychosis Association''s biannual meeting in Boston. More than 300 clinicians and other professionals working in the early psychosis care field attended the event. NIMH staff served on the planning committee and as presenters.
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Advisory Committee on Blood and Tissue Safety and Availability (ACBTSA)
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, OS
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CC, NHLBI
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The Advisory Committee on Blood and Tissue Safety and Availability (ACBTSA) is a 31-member federal advisory committee that provides advice to the Secretary of Health and Human Services through the Assistant Secretary for Health on a range of policy issues related to blood, blood products, and tissues.
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