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HIV Prevention Trials Network (HPTN) 065
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Research Initiative
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CDC
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NIAID, NIDA, NIMH
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HIV Prevention Trials Network (HPTN) 065 is a feasibility study of an enhanced testing, linkage to care, and treatment approach to HIV prevention in the U.S.
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HIV/AIDS Cancer Match Study
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Research Initiative
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CDC
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NCI
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Investigators have used data from the NCI HIV/AIDS Cancer Match Study, in conjunction with data from the CDC surveillance program on the number of HIV-infected people in the U.S., to estimate the contribution of the HIV epidemic to the occurrence of Kaposi sarcoma, non-Hodgkin lymphoma, and cervical cancer.
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Hospice to Palliative Care: Maximizing Patient Preferences and Cost Savings
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Research Initiative
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AHRQ
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CC
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The goal of the study is to provide rational, patient-defined, evidence-based recommendations to inform the redesign of the Medicare hospice benefit, transitioning policy from the current hospice benefit to a more patient-centered palliative care model.
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HPV Working Group for the Advisory Committee on Immunization Practices (ACIP)
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Committee, Work group, Advisory group, or Task Force
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CDC
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NCI
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HPV Working Group for the Advisory Committee on Immunization Practices ACIP Work Groups (WGs) serve in a key scientific role in support of vaccine policy development by the ACIP. ACIP WGs conduct extensive background reviews of relevant research data to develop options for recommendations for use of vaccines in the civilian population of the United States. WGs are convened solely to gather scientific information related to vaccines and the diseases they prevent, to analyze relevant issues and data, and to draft policies or options for review, deliberation and vote by the ACIP. The duties of this position include participation in teleconferences and meetings, as well as preparation time for these meetings.
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HRSA Interagency Committee On Emergency Medical Services For Children Research
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Committee, Work group, Advisory group, or Task Force
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CDC, HRSA
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NICHD
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This committee supports improving emergency medical services for child research.
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Human Immunology Project Consortium Collaboration on Mechanism Studies of Influenza Vaccination
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Research Initiative
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FDA
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NIAID
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The NIAID-funded Human Immunology Project Consortium (HIPC) supports an Infrastructure/Opportunity Fund (IOF) to create a shared research infrastructure for ongoing development of the immune profiling network, support collaborative projects, pilot projects, and new research opportunities for the HIPC investigators.
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IAA with CDC for HPTN 052: A Randomized Trial to Evaluate the Effectiveness of Antiretroviral Therapy plus HIV Primary Care versus HIV Primary Care Alone to Prevent the Sexual Transmission of HIV-1 in Serodiscordant Couples
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Other
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CDC
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NIAID
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These clinical studies are based on data collected in Africa and Thailand. There is a correlation between HIV viral load (blood levels) and HIV transmission. Specifically, the higher the viral load in the blood, the more likely the chance for transmission. Antiretroviral therapy (ART) reduces the viral load in the blood, as well as in genital secretions (for both men and women), and the drugs can be detected in semen and vaginal and cervical secretions. This information strongly suggests that ART may reduce the risk that HIV-infected people will transmit HIV. HPTN 052 compares the HIV-infection rates of two groups of HIV-serodiscordant couples.
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ICARE: Interagency Collaborative to Advance Research in Epilepsy
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Committee, Work group, Advisory group, or Task Force
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AHRQ, CDC, FDA, HRSA, OS
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NINDS, FIC, NCATS, NHGRI, NHLBI, NIA, NIAAA, NIAMS, NICHD, NIDA, NIMH
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The Interagency Collaborative to Advance Research in Epilepsy (ICARE) is an interagency epilepsy working group that includes broad representation across the NIH ICs involved in epilepsy-related research, as well as across HHS and other Federal agencies and multiple epilepsy research and patient advocacy groups with a primary focus on biomedical research. The purpose of this group, which is led by the National Institute of Neurological Disorders and Stroke, is to increase communication among institutes and agencies sponsoring epilepsy-related research and explore opportunities for increased coordination. The group’s annual meetings provide a forum for sharing information about ongoing and planned epilepsy research activities, highlighting advances, discussing needs and opportunities, and promoting increased collaboration toward common research goals.
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Image-guided Interventional Therapeutics
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Research Initiative
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FDA
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CC, NCI
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This collaboration will lead to safer and more effective treatment planning and performance of image-guided interventions and therapeutic drug delivery. The results of all of these studies of image guided interventions and related technologies and the models used to study them will have a direct impact on the effectiveness and consistency of the FDA Center for Devices and Radiological Health''s preclinical review of device applications while meeting the primary research goal of optimizing image guided interventions and pre-clinical modeling of those interventions. Regulatory science and translational therapeutics have overlapping goals when it comes to drugs and devices combination therapies.
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Improving Technical Standards and Molecular Tools for Probiotics Research and Development
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Research Initiative
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FDA
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NCCIH
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In 2008, the USDA Agricultural Service initiated a Memorandum of Understanding (MOU) with NCCAM to exchange expertise in technology development and partner research initiatives to advance the field of probiotic biology and role in human health. The MOU consists of a five year plan defining common mission goals; expected benefits from the exchange of research expertise and resources; and demonstration projects based on NIH/NCCAM funded U01 cooperative agreements. The long-term goal of the MOU is to develop trans-agency networked initiatives. In 2012, the unique resources of the USDA Agricultural Research Service and the Human Microbiome Project investigators were successfully implemented as a parallel comparative biotechnologies validation and standardization prototype with targeted molecular approaches.
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