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PRAMS Multi-Jurisdiction Data Linkage Learning Community
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Committee, Work group, Advisory group, or Task Force
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CDC, CMS, HRSA
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NICHD
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Support teams of PRAMS users building their internal capacity to link MCH data sets and inform their future programming.
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Precision Oncology Interest Group
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Committee, Work group, Advisory group, or Task Force
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FDA
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NCATS, NCI, NHLBI, NIAID, NIAMS, NIBIB, NICHD, NIDDK, NINDS
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The POIG, and its attendant listserv will aim to foster effective communication across the basic and clinical research oncology communities, to harness the translational powers of the NIH to advance precision therapy across cancers. The goals of the POIG are to discuss, plan, implement and execute the current CCR initiative to perform standardized genomic analyses (RNA-SEQ, exome-SEQ, methylation analysis) on a large cohort of NCI patients, with the goal of using these data to drive collaborative predictive and prognostic biomarker discovery and precision therapy strategies for improving patient outcomes, to discuss and implement best sample acquisition and management practices to learn the most from any precious patient material, to discuss and implement the best technologies and informatics to help us discover candidates for targeted therapies with the goal of maximizing favorable outcomes for oncology patients, and to rationally design clinical trials in oncology with a focus on precise therapies that have the potential to maximize benefit and minimize side effects.
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Predicting Drug Resistance with Machine Learning
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Research Initiative
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ASPE
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NIAID, NLM
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This project acquires, curates, and uses high-quality training data sets to predict tuberculosis (TB) drug resistance. TB drug resistance is concerning because it is difficult to diagnose in a patient during its early stages, and it complicates and prolongs treatment considerably. The project, conducted in collaboration with NIH’s National Institute of Allergy and Infectious Diseases and its TB Portals program, seeks to develop new ways of detecting drug resistance in chest radiographs by using deep learning in combination with large image repositories, clinical data, and genomic information of the bacteria for drug-sensitive and drug-resistant TB. Researchers use this data to train machine learning models that can detect signs of TB drug resistance. https://github.com/NLMLHC/NLM-PCOR-TB
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Pregnancy and Birth to 24 months (P/B-24) Project
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, HRSA, OS
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NCI, NHLBI, NICHD, NIDDK, NIEHS, NINR
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In 2012, the US Department of Agriculture (USDA) and Department of Health and Human Services (HHS) initiated a project informally called the “B-24 project.” This multi-phase project was originally intended to conclude in 2018 with information that could help the Departments develop dietary recommendations for infants and toddlers for release separate from the Dietary Guidelines. The first phase was completed in 2012-2013. In February 2014, Congress passed the Agricultural Act of 2014, also known as the Farm Bill, mandating that the Dietary Guidelines expand to include dietary guidance for infants and toddlers (from birth to age 24 months), as well as women who are pregnant, beginning with the 2020-2025 edition. Thus, USDA and HHS adjusted the purpose, timeline, and scope of the project. Now called the “Pregnancy and Birth to 24 Months project” or “P/B-24 project” to reflect the addition of pregnant women, this project is a joint initiative led by USDA and HHS in collaboration with programmatic and scientific experts. Rather than concluding in 2018 with dietary recommendations, the goal of the current project is to begin examining topics of public health importance for women who are pregnant and infants and toddlers from birth to 24 months of age. The findings from this work will be made publicly available at the completion of the project. https://www.fns.usda.gov/resource/pregnancy-and-birth-24-months
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President's Advisory Council for HIV/AIDS
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Committee, Work group, Advisory group, or Task Force
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CDC, HRSA, IHS, OASH, SAMHSA
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OD/DPCPSI/OAR
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The Presidential Advisory Council on HIV/AIDS (PACHA) provides advice, information, and recommendations to the Secretary of Health Human Services regarding programs, policies, and research to promote effective treatment, prevention and cure of HIV disease and AIDS, including considering common co-morbidities of those infected with HIV as needed to promote effective HIV prevention and treatment and quality services to persons living with HIV disease and AIDS.
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President's Emergency Plan for AIDS Relief (PEPFAR) Cervical Cancer Prevention Expert Task Force
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Committee, Work group, Advisory group, or Task Force
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Not Reported
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NCI, NIAID
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NCI participates with other US government agencies (Department of State, CDC, USAID, and others) on an expert task force to inform the development and oversight of cervical cancer prevention programs within the US President’s Emergency Plan for AIDS Relief (PEPFAR) initiative.The Department of State-convenes an Expert Task Force from experts from the CDC, NIH (NCI), and other US government agencies including Department of State, US Agency for International Development (USAID), Department of Defense, and Peace Corps to inform the development and oversight of cervical cancer prevention programs within the US President’s Emergency Plan for AIDS Relief (PEPFAR) initiative. The task force meets periodically to review progress and updates from focus countries in the PEPFAR cervical cancer prevention efforts, refines and updates guidance for screening and precancer treatment for implementing partners in target countries, and provides recommendations for procedures for quality assurance and adverse event monitoring and reporting.
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President's Management Agenda (PMA): Taking action on OPM FEVS results Sub-Working Group
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Committee, Work group, Advisory group, or Task Force
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Not Reported
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NIDDK
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Support engagement leaders in integrating OPM FEVS / agency engagement survey results into agency operations and leadership decision-making; Increasing communication of results and action to improve employee experience and improve response rates with the focus on Increasing Transparency, Improving Communication, Establishing Accountability, and Planning and Communicating Actions.
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President's Task Force on Environmental Health Risks and Safety Risks to Children
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Committee, Work group, Advisory group, or Task Force
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OASH, ACF, ASPR, ATSDR, CDC, FDA, SAMHSA
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NHLBI, NICHD, NIEHS, NIMH, NIMHD, OD/ECHO
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In 1997, President Clinton issued Executive Order 13045, calling for each federal agency to ensure that its policies, programs, activities, and standards address disproportionate risks to children that result from environmental health risks or safety risks.” EO13045 established the President’s Task Force on Environmental Health Risks and Safety Risks to Children (Task Force).The Task Force has addressed issues such as childhood asthma, unintentional injuries, lead poisoning, developmental disorders, childhood cancer, and climate change. The Task Force also recommended the initiation of a prospective cohort study, from birth to adulthood, to evaluate the effects of both environmental exposures on child health and human development. An interdepartmental working group of senior staff was established to support the work of the Task Force—the Senior Staff Steering Committee (Steering Committee). It is co-chaired by the U.S. Environmental Protection Agency (EPA) and the Department of Health and Human Services (HHS). Working together through the Task Force, the federal government can continue to protect current and future generations by understanding and preventing negative environmental health impacts and helping to ensure opportunities for the development of healthy, more resilient children.
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President's Task Force on Environmental Health Risks and Safety Risks to Children, Chemical Exposures Subcommittee
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Committee, Work group, Advisory group, or Task Force
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Not Reported
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NIEHS, NINDS
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The goal of the PTF on Environmental Health Risks and Safety Risks to Children Chemical Exposures Subcommittee is to coordinate federal research and action to address early-life exposures to chemicals that impact children’s health, such as the development of methods and models to enhance exposure assessment relevant to public health.https://ptfcehs.niehs.nih.gov/activities/chemical-exposures
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President's Task Force on Environmental Health Risks and Safety Risks to Children, Subcommittee on Climate, Emergencies, and Disasters
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Committee, Work group, Advisory group, or Task Force
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ACF, ASPR, CDC, HRSA, OASH
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NHLBI, NICHD, NIEHS
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In 1997, President Clinton issued Executive Order 13045, calling for each federal agency to “ensure that its policies, programs, activities, and standards address disproportionate risks to children that result from environmental health risks or safety risks.” EO13045 established the President’s Task Force on Environmental Health Risks and Safety Risks to Children (Task Force). Subcommittee on Climate, Emergencies, and Disasters. The new Subcommittee on Climate, Emergencies, and Disasters within the PTFCEH aims to address current gaps in health protection, promotion and research related to children resulting or arising from climate change, public health emergencies, and disasters. Dr. Dixon is a Co-Chair. https://ptfceh.niehs.nih.gov/
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