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Cell Therapy for Lung Diseases
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Meeting/ Workshop
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FDA
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NHLBI
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Acute and chronic lung diseases are leading causes of morbidity, mortality, and health care expenditures. Innovative approaches for therapies are urgently needed. Increasingly, patients who suffer from chronic lung diseases are seeking stem cell therapies outside the U.S. due to limited opportunities to participate in clinical studies of stem cells in the U.S. The current NHLBI portfolio on lung stem and progenitor cells has focused primarily on basic research to build fundamental knowledge of the role of stem/progenitor cells in lung disease and injury/repair. However, clinical application of cell therapy for lung diseases will require a more focused approach that coordinates basic research with translational research to facilitate cell-based clinical trials.
Therefore, the NHLBI convened a Cell Therapy for Lung Diseases working group on November 13-14, 2012 to make recommendations for future research directions. The workshop brought together investigators who study basic mechanisms including cell therapy in preclinical models of lung injury/disease along with clinical trial experts in cell therapy for cardiovascular indications and experts from NHLBI’s Production Assistance for Cell Therapy (PACT) program.
The overall objective was to discuss the current status of basic investigations in lung cell therapy, identify the scientific gaps in current knowledge regarding cell therapy in the treatment of lung diseases, and develop recommendations to the NHLBI and the research community on scientific priorities that would facilitate high quality, rigorous first-in-human trials of lung cell therapy.
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CFAR Enhanced Comprehensive HIV Prevention Planning (ECHPP) Administrative Supplement: Project 2
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Research Initiative
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CDC
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NIAID, NIMH
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The purpose of this administrative supplement to the NIH Centers for AIDS Research (CFAR) is to provide funding to conduct operational research around the ECHPP funded by the CDC. This supplement provided funds to stimulate collaboration between the CFARs and the local health departments in the ECHPP project to help implement the National HIV/AIDS Strategy.
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Characterizations of Fungal Exposures
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Research Initiative
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CDC
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NIEHS
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These studies address the limitations in traditional methods for assessing fungal exposures by using molecular techniques to identify fungi in dust samples and biological fluids.
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Chemical Integrated Program Team (IPT)
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Other
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CDC, FDA, OS
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NICHD
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This workgroup is a Public Health Energy Enterprise. The Integrated Program Team (IPT) working group provides an end-to-end vision of medical countermeasures needed for a particular threat type (e.g., anthrax, rad/nuc, etc.). The scope of their work includes setting requirements for the stockpiling of medical countermeasures (MCMs), MCM delivery and dispensing and monitoring MCM development. The IPTs also advise the Enterprise Executive Committee as to threat- or capability-specific MCM priorities for improving preparedness, to inform leadership consideration of cross-threat prioritizations and strategic goal setting.
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CHEMM (Chemical Hazards Emergency Medical Management)
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Resource Development
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ATSDR, CDC, OS
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NLM
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This activity is to develop a comprehensive web resource: Chemical Hazards Emergency Medical Management (CHEMM) is a tool designed to provide access to comprehensive sets of information about chemical hazards via a user-friendly interface.
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Child Abuse and Neglect Working Group (CANWG)
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Other
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ACF, HRSA, SAMHSA
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NICHD, CSR, NIAAA, NIDA, NIMH, NINDS, OD/DPCPSI/OBSSR
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The NIH Child Abuse and Neglect Working Group (CANWG) was established in response to a recent directive by the House Committee on Appropriations, which requested that NIH report on current NIH efforts, accomplishments, and future plans for research on child abuse and neglect. The CANWG is co-chaired by program staff from NICHD and NIDA (formally NIMH). The working group is also a subcommittee of the Federal Interagency Workgroup on Child Abuse and Neglect.
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Children''s HHS Interagency Leadership on Disasters (CHILD) working group
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Other
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ACF, OS
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NICHD
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The potential impact of disasters on children can extend from the immediate response phase of a disaster through the recovery phase, creating many challenges but also many opportunities to mitigate the effects. The U.S. Department of Health and Human Services (HHS) established the Children’s HHS Interagency Leadership on Disasters (CHILD) Working Group in 2010 to identify and comprehensively integrate the activities related to the needs of children across all HHS inter- and intra-governmental disaster planning activities and operations. Co-led by the Administration for Children and Families (ACF) and the Assistant Secretary for Preparedness and Response (ASPR), the group developed recommendations for how HHS can improve the delivery of care to children who are impacted by disasters. The Working Group is divided into four subcommittees: 1) Mental and Behavioral Health, 2) Medical Countermeasures, 3) Child Physical Health, Emergency Medical Services, and Pediatric Transport, and 4) Child Care and Child Welfare.
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Children’s Mental Health: Surveillance of mental disorders among children in the United States (CDC MMWR Special Report)
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Other
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CDC, HRSA, SAMHSA
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NIMH
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The Centers for Disease Control and Prevention initiated a special Morbidity and Mortality Weekly Report (MMWR) on child mental health surveillance. This report will provide a first and comprehensive look at surveillance systems that collect data on mental health issues. The report summarizes information about ongoing federal surveillance systems that can provide estimates of the prevalence of mental disorders and indicators of mental health among children living in the United States, and presents estimates of childhood mental disorders and indicators from these systems during 2005-2011.
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Chronic Fatigue Syndrome Advisory Committee (CFSAC)
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Committee, Work group, Advisory group, or Task Force
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AHRQ, CDC, CMS, FDA, HRSA, OS
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OD/DPCPSI/ORWH, CSR, NCATS, NCI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIDCR, NIDDK, NIEHS, NIMH, NINDS, NINR, NLM
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The Chronic Fatigue Syndrome Advisory Committee (CFSAC) provides advice and recommendations to the Secretary of Health and Human Services via the Assistant Secretary for Health of the U.S. Department of Health and Human Services on issues related to chronic fatigue syndrome (CFS). These include: 1) factors affecting access and care for persons with CFS; 2) the science and definition of CFS; and 3) broader public health, clinical, research and educational issues related to CFS.
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Clinical and Translational Research Course for PhD Students
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Training Initiative
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FDA
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CC, NCATS, NCI, NHLBI, NIAID, NIDDK, NIGMS, NIMH
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The Clinical and Translational Research Course for Ph.D. Students is a two-week intensive introductory course for graduate students in the basic biomedical sciences who have at least one year of graduate study. The purpose of the course is to demonstrate and highlight the roles of PhD scientists in clinical and translational research, to provide an overview and examples of how basic science and clinical observations lead to translational research, and to increase awareness and access to Ph.D. role models, research resources, and potential career opportunities at the NIH.
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