|
AREDS2 Nutritional Biochemistry Substudy
|
Research Initiative
|
CDC
|
NEI
|
Age-Related Eye Disease Study 2 (AREDS2) is an NEI-funded multi-center randomized trial designed to assess the effects of oral supplementation of high doses of macular xanthophylls and/or omega-3 for the treatment of Age related macular degeneration (AMD) and cataract. This will be accomplished by collecting and assessing the data on approximately 4,000 AREDS2 participants aged 50 to 85 years, who at the time of enrollment have either: 1) bilateral large drusen or 2) large drusen in one eye and advanced AMD in the fellow eye. The CDC serves as the AREDS2 Central Laboratory for the Nutritional Biochemistry Substudy. Serum and plasma samples for all AREDS2 participants at participating Clinical Centers are sent to the Central Laboratory for measurement of concentrations of vitamins A and E (alpha - & gamma - tocopherol), lutein, zeaxanthin, α - and β - carotene, β - cryptoxanthin, lycopene (trans - and total), selected fatty acids (including DHA and EPA), lipids (including cholesterol and triglycerides), zinc and copper.
|
|
Assistance for Orphans and Other Vulnerable Children in Developing Countries Act of 2005 (PL 109-95) Interagency Work Group
|
Other
|
ACF, CDC, HRSA
|
NICHD, FIC, NIMH
|
This congressionally mandated workgroup evaluates efforts on behalf of orphans and underserved children worldwide.
|
|
Asthma Outcomes Workshop
|
Meeting/ Workshop
|
AHRQ, CDC, CMS, FDA, HRSA
|
NHLBI, NIA, NIAID, NICHD, NIEHS, NIMHD, NINR
|
This workshop established standard definitions and data collection methodologies for validated outcome measures in asthma clinical research. The workshop also identified promising outcome measures and discussed the status of their development and validation.
|
|
Asthma Supplement to the National Ambulatory Medical Care Survey (NAMCS)
|
Health Survey
|
CDC
|
OD/OSP, NHLBI, NIAID, NICHD, NIEHS
|
The National Ambulatory Medical Care Survey (NAMCS) Asthma Supplement is a national survey of physician''s opinions about and use of the National Asthma Education and Prevention Program (NAEPP) Guidelines for the Diagnosis and Management of Asthma. The NIH and the CDC''s National Center for Health Statistics collaborate on this activity.
|
|
Auditory (Hearing) Screening Supplement for the Early Childhood Longitudinal Study -Kindergarten Cohort
|
Health Survey
|
CDC
|
NIDCD
|
The objective of this Inter-Agency Agreement is to develop a hearing examination protocol to implement hearing tests in the Early Childhood Longitudinal Study of the Kindergarten Class of 2010–11. This is a large (n=20,000), nationally representative school-based exam and interview survey sponsored by the National Center for Education Statistics (NCES), U.S. Department of Education. The last NCES longitudinal cohort study of school age children began with the 1998 Kindergarten Class. In this earlier cohort, there were no hearing exams (nor vision exams) and the number of young children with hearing loss (reported by parents or teachers) shrank considerably after the initial enrollment of Kindergarteners. In the U.S., the last comprehensive national study of children with hearing exam measures was the 1963–1965 National Health Examination Survey (NHANES predecessor) for children aged 6 to 11 years. The Epidemiology Branch, NEI, is sponsoring development of a vision exam protocol to be used in conjunction with the hearing exam protocol. Visual refractive error will be tested with the automated objective refraction device, Retinomax K-plus 2, using the manufacturer’s directions. When children are identified with hearing (or vision) loss early in the study, they will be included in a “selected” (protected) subsample for more intensive tracking in follow-up waves of the survey. Children in the selected subsample will be tracked to new schools if they are subsequently enrolled in a school that was not in the original school sample, e.g., when families relocate. In addition to hearing and vision, the ECLS-K:2010-11 will track several other outcome measures (e.g., general health, social and physical development, achievement scores, and communication problems) associated with educational performance. Hearing and vision will be tested when the children are examined in the school setting. NCES has awarded a contract to WESTAT to conduct the field operations, including selection of sample schools, data collection, and preparation of user-friendly research data files. The contractor will obtain measures of hearing sensitivity, middle ear function, and visual refractive errors of Kindergartners once during the Kindergarten year. Hearing thresholds will be recorded from each ear separately. In addition, the contractor will obtain tympanometric traces to assess middle ear function. (ADC12005001-1-0-0)
|
|
Autoimmune Diseases Coordinating Committee (ADCC)
|
Committee, Work group, Advisory group, or Task Force
|
CDC, FDA, HRSA
|
OD/OSP, CSR, FIC, NCATS, NCCAM, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NINDS, NINR
|
The purpose of the Autoimmune Diseases Coordinating Committee (ADCC) is to provide a forum for the coordination of research efforts in autoimmunity and autoimmune diseases among various stakeholders including the NIH, other federal agencies such as the FDA and the CDC, and private organizations with an interest in autoimmune diseases. The ADCC meets twice yearly to discuss a broad range of basic, preclinical and clinical endeavors.
|
|
Avian Influenza Collaborative Project
|
Research Initiative
|
CDC, OS
|
FIC
|
This multinational research is aimed at modeling the transmission dynamics of Avian Influenza (AI) spill-over from birds to humans using field data from different regions (Asia, Africa, Latin America). The expected project output is an ecological model for AI spill-over which will help us predict these events as well as inform and focus our global Avian and Pandemic Influenza prevention and response activities. This project, supported through Global Influenza funding from HHS, is one of the few multi-national ecological studies to develop an understanding of the critical elements of spillover and transmission of influenza which integrates diverse fields of expertise (ecologists, geospatial technology experts, modelers, virologists, and epidemiologists) and which is intended to produce a predictive model. It also supports capacity building for collaborating scientists on these three continents. By providing supplements to Fogarty grantees, this activity leverages FIC''s multi-disciplinary network of current grantees, and it promotes sample and data sharing.
|
|
Basic Social and Behavioral Research on Culture, Health, and Wellbeing
|
Committee, Work group, Advisory group, or Task Force
|
AHRQ
|
OD/DPCPSI/OBSSR, FIC, NCATS, NCCAM, NCI, NCMHD, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM
|
Planning group to explore opportunity for joint funding opportunity among NIH/OppNet, US National Endowment for the Humanities, UK''s Arts and Humanities Research Council, and the Wellcome Trust (UK)
|
|
Behavioral Aspects of Prep Counseling HIV Prevention Trials Network (HPTN) Protocol #067: The ADAPT Study (Y01-MH-0315)
|
Research Initiative
|
CDC
|
NIMH, NIAID
|
This behavioral research study is evaluating whether non-daily medication regimens for HIV Pre-Exposure Prophylaxis (PrEP) may be more acceptable and foster better adherence to product. PrEP represents a novel biomedical approach to HIV prevention, in which individuals at-risk for HIV take antiretroviral medications to help prevent HIV infection. The HPTN 067 study is conducted through the NIAID-led HIV Prevention Trials Network. An Inter-Agency Agreement between NIMH and CDC supports the implementation of this international research study at a clinical research site in Bangkok Thailand.
|
|
Best Pharmaceuticals for Children Act
|
Research Initiative
|
FDA, HRSA
|
NICHD, NHLBI, NIMH
|
The Best Pharmaceuticals for Children Act (BPCA) Program is a major activity for the Obstetric and Pediatric Pharmacology and Therapeutics Branch (OPPTB) at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). OPPTB is responsible for developing and supporting a comprehensive national research and training effort to increase the knowledge base for understanding how to appropriately treat disease during pregnancy, infancy, and childhood using pharmaceuticals that are appropriately tested within their target populations. NICHD activities related to BPCA are intended to improve pediatric drug therapeutics through preclinical and clinical testing that lead to drug labeling changes. We are performing pediatric clinical trials in order to submit data to FDA for labeling changes. BPCA is a partnership with FDA, to a degree.
|