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Antiretroviral Pregnancy Registry
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Resource Development
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CDC, FDA, HRSA
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NICHD
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This is a registry of use of antiretroviral drugs in pregnancy that is sponsored by various pharmaceutical companies and has a committee of external experts and government staff from the National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and Food and Drug Administration (FDA). The registry provides a resource for clinicians and researchers to improve the healthcare quality and patient safety for HIV infected mothers and their infants.
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Asia-Pacific Economic Cooperation (APEC) Cervical Cancer Initiative
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Meeting/ Workshop
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OS
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NCI
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NCI and the Office of the Secretary have been supporting a collaborative effort to strengthen cervical cancer control through the Asia-Pacific Economic Forum (APEC). Effective cervical cancer control strategies exist all along the cervical cancer control continuum, including primary prevention, screening, treatment, and palliative care. Recent research has demonstrated the effectiveness of lower cost screening techniques, and ongoing research is exploring additional reduced-cost cervical cancer control options. The large number of interventions currently available and on the horizon means that the integration of these approaches into health systems is possible for economies of many different resource levels and can have substantial impact on public health, the workforce, and the broader economy.
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Assay Guidance Workshop For High Throughput Screening And Lead Discovery
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Meeting/ Workshop
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FDA
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NCATS, CC, NCI, NEI, NHGRI, NHLBI, NIAID, NIAMS, NICHD, NIDA, NIDCR, NIDDK, NINDS
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More than 100 participants attended the “Assay Guidance Workshop for High-Throughput Screening and Lead Discovery” on April 5–6, 2016, in College Park, Maryland. Hosted by NCATS and the Food and Drug Administration (FDA), the workshop was designed to provide participants with a broad and practical perspective on how to develop and implement robust assays for early-stage drug discovery projects. Participants included researchers from thirteen NIH centers, FDA, National Institute of Standards and Technology, the Department of Defense, industry and academia. Workshop leaders with more than 20 years of drug discovery experience covered a broad range of critical concepts underlying robust assay development and screening strategies. There were also open discussions for participants to share experiences and seek practical advice about individual research interests.
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Assessment of Occupational Exposure to Coal Tar Pitch Volatiles Containing Polycyclic Aromatic Hydrocarbons (PAHs) in Coal Tar Sealant Applications
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Research Initiative
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CDC
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NIEHS
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This study is a collaboration between NIH and CDC that is measuring exposure of coal tar sealant applicators to polycyclic aromatic hydrocarbons (PAHs) compounds.
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Assessment of Occupational Exposure to Flame Retardants
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Research Initiative
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CDC
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NIEHS
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This study aims to characterize occupational exposure to flame retardants among U.S. workers who are manufacturing or installing flame retardant materials.
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Assisted Outpatient Treatment
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Research Initiative
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HRSA, SAMHSA
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NIMH
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This collaboration supports the development and implementation of a rigorous and objective cross-site impact evaluation of an Assisted Outpatient Treatment (AOT) Grant Program for Individuals with Serious Mental Illness. The Department of Health and Human Services, Assistant Secretary for Planning and Evaluation (ASPE) has primary responsibility for the solicitation, management, and implementation of the evaluation contract in consultation with the Substance Abuse and Mental Health Services Administration (SAMHSA) and the National Institute of Mental Health (NIMH). The Center for Behavioral Health Statistics and Quality (CBHSQ), an entity within SAMHSA that serves as a focal point for data collection, analysis, and the dissemination of critical public health data, will provide consultation on the cross-site evaluation of the AOT grant program. ASPE, in consultation with the NIMH, brings expertise in evaluation design and implementation that benefits SAMHSA in its priority of having a rigorous multi-site evaluation. The objective of the multi-site evaluation is to measure the effectiveness of the AOT programs in improving rates of appropriate health care utilization and reducing rates of incarceration, health care utilization, and homelessness for individuals with serious mental illness, and to identify key program components.
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Association Between Urinary PAH and Esophageal Squamous Dysplasia in the STEP study in Western Kenya
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Research Initiative
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CDC
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NCI
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This activity is a collaboration between NCI and CDC that aims to measure metabolites of polycyclic aromatc hydrocarbons (PAHs), cotinine and creatinine in the urine samples from individuals with and without precancerous lesions of the esophagus.
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ASTM International F-2529-13--Standard Guide for In-Vivo Evaluation of Osteoinductive Potential for Materials Containing Demineralized Bone (DBM)
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Research Initiative
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FDA
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NIDCR
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Provide a guide based on consensus of viewpoints used to determine the osteoinductive potential of a DBM containing products utilizing the arthymic rodent model.
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Auditory (Hearing) Screening Supplement for Early Childhood Longitudinal Study
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Health Survey
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CDC
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NIDCD
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The objective of this Inter-Agency Agreement is to implement a hearing examination protocol in the Early Childhood Longitudinal Study of the Kindergarten Class of 2010–11. This is a large (n=20,000), nationally representative school-based exam and interview survey sponsored by the National Center for Education Statistics (NCES), U.S. Department of Education. The last NCES longitudinal cohort study of school age children began with the 1998 Kindergarten Class. In this earlier cohort, there were no hearing exams (nor vision exams) and the number of young children with hearing loss (reported by parents or teachers) shrank considerably after the initial enrollment of Kindergarteners. A randomly selected sub-sample of about 4500 children were identified for more frequent follow-up and these children have also been selected for the hearing examination; they are also included in a “selected” (protected) subsample for more intensive tracking in follow-up waves of the survey. Children in the selected subsample will be tracked to new schools when possible if they are later enrolled in (moved to) a school that was not in the original school sample, e.g., when families relocate. In addition to hearing, the ECLS-K: 2010-11 will track several other outcome measures (e.g., general health, social and physical development, achievement scores, and parental and teacher-reported communication problems) associated with educational performance. Hearing will be tested when the children are examined with achievement testing in the school setting.
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Autoimmune Diseases Coordinating Committee
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, HRSA
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NIAID, CSR, FIC, NCATS, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NINDS, NINR
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The purpose of the Autoimmune Diseases Coordinating Committee (ADCC) is to provide a forum for the coordination of research efforts in autoimmunity and autoimmune diseases among various stakeholders including the NIH, other federal agencies such as the FDA and the CDC, and private organizations with an interest in autoimmune diseases. The ADCC meets twice yearly to discuss a broad range of basic, preclinical and clinical endeavors.
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