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Big Data to Knowledge (BD2K)
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Research Initiative
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AHRQ, CMS, FDA, OS
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OD/DPCPSI, CC, CIT, CSR, FIC, NCATS, NCCIH, NCI, NCMHD, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, OD/DPCPSI/OAR, OD/DPCPSI/OBSSR, OD/DPCPSI/ODP, OD/DPCPSI/ORIP, OD/DPCPSI/ORWH, OD/DPCPSI/OSC, OD/OCPL, OD/OER, OD/OIR, OD/OIR/OTT, OD/OLPA, OD/OM/OB, OD/OSP
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The Big Data to Knowledge (BD2K) program aims to facilitate broad use of biomedical big data, develop and disseminate analysis methods and software, enhance training for disciplines relevant for large-scale data analysis, and establish centers of excellence for biomedical big data. In FY 2014, BD2K held discussions with several HHS agencies who have shared interests in Big Data.
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Biomarkers Reflecting Inflammation and Nutrition Determinants of Anemia (BRINDA) project
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Research Initiative
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CDC
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NICHD, NIAID
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The primary focus of our collaborations stemming from the Iron and Malaria project is now the, Biomarkers Reflecting Inflammation and Nutrition Determinants of Anemia (BRINDA) project. This project involves a meta-analyses of national surveys from 17 countries to examine the relationship between inflammation and biomarker performance/interpretation with specific regard to iron and vitamin A. It also includes an examination of other non-iron determinants of anemia in these low resource settings. As anemia prevalence often serves as a "trigger" for population-based interventions particularly iron supplementation it is critical given current concerns about the safety and efficacy of iron to ensure that such triggers accurately reflect the target problem. CDC has assumed a major role in the conduct of the BRINDA study with technical and financial support of NICHD.
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Bioresource Development, Validation Tools, and Integrating High-Throughput Screening Technology Standards in Complementary and Alternative Medicine (CAM) Product Use in Children
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Research Initiative
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CDC, HRSA, SAMHSA
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NCCIH, NICHD
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Collaborative efforts between the FDA/CBER and the NIH/NCCAM for substantiating health benefit claims for probiotics under Investigational New Drug Applications (INDs) were placed in the framework of U01 Cooperative Agreements that began in 2008. The successful evaluation of the initiative has recently developed into an invitation to develop a Memorandum of Understanding (MoU) to promote resource sharing and exchange of research expertise; development of demonstration project(s); and the initiation of trans-agency research initiatives focused on the integration of advanced molecular technologies that lead to harmonization standards and improved diagnostics for safety and substantiation of the health benefits of probiotic interventions. In 2011, a collaboration with FDA/CFSAN was initiated to expand the validation tool. In 2012, a Materials Transfer Agreement [MTA] was approved and the FDA/CFSAN received the entire data collection to undergo testing employing their novel microarray multi-loci sequence testing system [MLST].
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Biosafety Infectious Disease
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Training Initiative
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CDC
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NIEHS
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Improve nation capacity to reduce illness and injury as a result of potential exposure to infectious pathogens
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Board of Scientific Counselors, CDC''s National Center for Injury Prevention and Control
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Committee, Work group, Advisory group, or Task Force
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CDC
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NIA
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An NIA representative serves on the Board of Scientific Counselor’s for the Centers for Disease Control and Prevention (CDC) National Center for Injury Prevention and Control. The NIA representative brings expertise in research on older adults.
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Body Mass and Mortality Relationships
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Research Initiative
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CDC
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NCI
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A study of the relationships between categories of body mass and mortality in the U.S. population.
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Brain Attack Coalition
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Committee, Work group, Advisory group, or Task Force
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CDC
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NINDS
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The Brain Attack Coalition (BAC) is a group of public and private entities representing medical, scientific, advocacy, and government professionals from across the stroke continuum. The BAC is dedicated to setting direction, advancing knowledge, and communicating best practices to improve our ability to prevent and combat stroke.
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Breastfeeding and Human Lactation Research Scientific Interest Group (BALSIG) Special Interest Group
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Other
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FDA, OSG
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NICHD, NCI, NIDDK, OD/DPCPSI/ORWH
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In August 2012, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) formed a trans-U.S. Department of Health and Human Services (HHS) scientific interest group, Breastfeeding and Human Lactation Research Scientific Interest Group (BALSIG), to provide an intellectual platform for the scientists from HHS agencies interested in breastfeeding and human lactation research activities.
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Burkholderia Interagency Working Group
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Committee, Work group, Advisory group, or Task Force
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OS
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NIAID
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This interagency working group coordinates activities related to the Burkholderia research portfolios of NIAID, Biomedical Advanced Research and development Authority (BARDA), and Defense Threat Reduction Agency, and shares data related to the regulatory pathway of existing and novel medical countermeasures against melioidosis and glanders.
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Cancer and Women''s Health Interagency Agreement
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Research Initiative
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FDA
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NCI
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This formal agreement (MoU) establishes the framework and procedures to enhance collaborations and exchange of information between the FDA’s Office of Women’s Health (OWH) and the NCI’s Center to Reduce Cancer Health Disparities (CRCHD). Working together, FDA and NCI seek to increase scientific knowledge and understanding of cancer in women through targeted basic, clinical, bio-behavioral, translational, and community-based participatory research approaches/efforts. FDA and NCI both recognize the need for a unified approach to advancing scientific knowledge related to cancer and women’s health. This harmonized approach will aid in advancing the public health of all women through innovation in cancer research and medical therapies.
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