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President’s Emergency Plan for AIDS Relief (PEPFAR) Public Health Evaluation Activities
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Research Initiative
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CDC, HRSA, SAMHSA
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NIAID, FIC, NCI, NIAAA, NIDA, NIMH, OD/DPCPSI/OAR
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The President''s Emergency Plan for AIDS Relief (PEPFAR) is governed by intra-agency groups, which include the National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and Health Resources and Services Administration (HRSA) for the U.S. Department of Health and Human Services (HHS). CDC has a large role as an implementing partner for PEPFAR, while NIH has limited its activities to providing technical expertise on issues related to safety and efficacy of elements for PEPFAR programs, and to facilitating evaluation of PEPFAR through NIH funded investigators. The agencies work together to assist in developing research and evaluation priorities for PEPFAR. Awards through NIH Institutes and Centers address specific questions and data analysis requests.
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Prevention Research Centers
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Research Initiative
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CDC
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NCI
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The Prevention Research Centers program funds community-based research projects at 37 academic research centers across the U.S.; 5 developmental and 32 comprehensive centers. These centers: Conduct research projects that promote health and prevent disease; Build research teams of multidisciplinary faculty; Seek solutions, strategies, and policies that address public health problems; Participate in research networks that address priority health issues, such as healthy aging, cancer prevention & control, and obesity prevention; Build long-term relationships for engaging communities as partners in research; Conduct research in directions guided by advisory boards of community leaders; Develop and deliver trainings that enhance the public health workforce; and Conduct additional research funded by other federal agencies, foundations, and nonprofit organizations.
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Prevention Research Coordinating Committee
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Committee, Work group, Advisory group, or Task Force
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AHRQ, ATSDR, CDC, OS
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OD/DPCPSI/ODP, CC, CIT, CSR, FIC, NCATS, NCCAM, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, OD/DPCPSI/OAR, OD/DPCPSI/OBSSR, OD/DPCPSI/ORWH, OD/OLPA
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The National Institutes of Health (NIH) Prevention Research Coordinating Committee (PRCC) serves as a venue for exchanging programmatic and scientific information of interest to the NIH, as well as for planning and implementation of collaborative activities. The PRCC promotes prevention research designed to yield results directly applicable to identifying and assessing risk, and to developing interventions for preventing or ameliorating high-risk behaviors and exposures, the occurrence of disease/disorder/injury, or the progression of detectable but asymptomatic disease. Prevention research also includes research studies to develop and evaluate disease prevention and health promotion recommendations and public health programs.
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Prevention Scientists Promoting Global Health: Emerging Visions for Today and Tomorrow
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Meeting/ Workshop
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CDC
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NIAAA, NCI, NHLBI, NICHD, NIDA, NIMH
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The Society for Prevention Research (SPR) envisions a wellness-oriented society in which evidenced-based programs and policies are continuously applied to improve the health and well-being of its citizens. The SPR Annual Meeting provides unique opportunities to advance this vision by providing an integrated forum for the exchange of new concepts, methods, and results from prevention and public health-related research, and communication between scientists, public policy leaders and practitioners concerning the implementation of evidence-based preventive interventions.
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Prevention with Positives Intervention HIV Clinics (Y01-MH-1318)
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Research Initiative
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CDC
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NIMH, NIAID
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The Prevention with Positives Intervention HIV Clinics is a contract with the Centers for Disease Control and Prevention to conduct an HIV clinic-based comparison of a comprehensive prevention program for people living with HIV targeting multiple health behaviors (sexual risk, medication adherence, clinic attendance) and health outcomes (viral load, retention in care).
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Public Health Emergency Medical Countermeasures Enterprise (PHEMCE)
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Committee, Work group, Advisory group, or Task Force
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ACF, CDC, FDA, OS, SAMHSA
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NIAID, NIAMS, NICHD, NINDS, NLM
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The Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) determines the various medical countermeasures (MCMs) that are needed and oversees their development and procurement. The PHEMCE also advances national preparedness against chemical, biological, radiological, nuclear (CBRN) and emerging infectious disease (EID) threats, including pandemic influenza, by coordinating medical countermeasure related efforts within U.S. Department of Health and Human Services (HHS) and in cooperation with interagency PHEMCE partners. In order to accomplish this objective, the PHEMCE uses a multitier approach. Each tier comprises multiple agencies within HHS and/or the Department of Homeland Security (DHS) that work together in a collaborative fashion to further the preparedness of the nation. The first tier includes the Biological, Chemical, Radiological/Nuclear Working Groups; the Blood/Tissue MCM Requirements Working Group; and Integrated Program Teams (IPTs). The Working Groups (WG) utilize scenario-based analyses to determine which MCMs are needed for the Strategic National Stockpile (SNS), or affiliated repositories. The IPTs provide an end-to-end vision of MCMs needed for a particular threat type (e.g., anthrax, radiological/nuclear, etc.). The scope of their work includes setting requirements for the stockpiling of MCMs, MCM delivery and dispensing and monitoring MCM development. The IPTs also advise the Enterprise Executive Committee (EEC)as to threat- or capability-specific MCM priorities for improving preparedness, to inform leadership consideration of cross-threat prioritizations and strategic goal setting. Agencies represented on the PHEMCE WGs and IPTs include: National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), U.S. Food and Drug Administration (FDA), Department of Defense (DOD), Office of the Assistant Secretary for Preparedness and Response (ASPR), Biomedical Advanced Research and Development Authority (BARDA), DHS, and Department of Veterans Affairs (VA). The second tier of this process is the EEC. The EEC is comprised of senior program managers across the partner agencies. It provides the critical interface and organizing capability between the strategic focus of the Enterprise Senior Council (ESC) and the tactical-level efforts conducted within the subordinate IPTs and WGs. This committee serves as a Senior Advisor-level coordination mechanism across the Federal agencies involved in PHEMCE-related activities to facilitate vetting and prioritization of policy decision materials to be presented to the ESC. The third and most senior tier of the PHEMCE and the forum for cooperation and overall mission fulfillment is the ESC. Structurally, the ESC is led by the Assistant Secretary for Preparedness and Response and comprised of the senior leadership of National Institute of Allergy and Infectious Diseases (NIAID) within NIH, CDC, and FDA with comparable senior level representatives from the DoD, DHS, VA, and the U.S. Department of Agriculture (USDA). As the most senior level in the PHEMCE structure, this group approves major policies, product requirements, and large-scale procurement actions. It also oversees strategic reviews of the activities in each of the major threat portfolios (e.g., anthrax, smallpox, radiological/nuclear) and is the final reporting body for high priority actions identified as gaps in these reviews.
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Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) Chemical Integrated Product Development Team (IPT)
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, OS
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NINDS, NIAID
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The U.S. Department of Health and Human Services (HHS) Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) leads the mission to develop and acquire medical countermeasures that will improve public health emergency preparedness as well as prevent and mitigate the adverse health consequences associated with chemical, biological, radiological and nuclear (CBRN), and naturally occurring threats.
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Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) Chemical Requirements Working Group
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, OS
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NINDS, NIAID, NICHD, NIEHS
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The U.S. Department of Health and Human Services (HHS) Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) leads the mission to develop and acquire medical countermeasures that will improve public health emergency preparedness as well as prevent and mitigate the adverse health consequences associated with chemical, biological, radiological and nuclear (CBRN), and naturally occurring threats.
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Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) Enterprise Executive Committee (EEC)
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, OS
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NIAID
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The Enterprise Executive Committee (EEC) is responsible for overseeing Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) operations. The EEC ensures that important PHEMCE programmatic, procurement, requirements, and portfolio actions are fully vetted and that any recommendation or action is clearly delineated and properly approved. Additionally, the EEC manages the work at the various Integrated Program Teams and subgroup levels, directly manages the annual assessment of the Strategic National Stockpile, and composes PHEMCE documents, such as the Strategy and Implementation Plan.
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Public Health Prevention of HIV Risk Behaviors Technical Working Group
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Committee, Work group, Advisory group, or Task Force
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CDC, SAMHSA
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NIAAA, NIDA
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Collaboration with the Office of Global AIDS Coordination, Centers for Disease Control and Prevention to identify and implement effective HIV prevention and treatment interventions among alcohol abusing and dependent populations.
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