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NTP Technical Report on the Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophenone (CAS No. 131-57-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats
| Document, Report, or Other Product Information | |
|---|---|
| Title: | NTP Technical Report on the Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophenone (CAS No. 131-57-7) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats |
| Subject: | NTP assessed the potential of continual exposure to 2-hydroxy-4-methoxybenzophenone (2H4MBP) via the diet to induce developmental toxicity, affect reproductive performance (e.g., pregnancy rate, litter size), and alter endocrine-sensitive endpoints, and included histopathological examination of the adult F1 male and female reproductive tracts. |
| Purpose (e.g., abstract): | This peer review done via panel will be conducted in Q2 2021. It will assess of the draft NTP developmental and reproductive toxicity technical report (DART-05). Information for the review will be posted once dates are finalized. |
| Information Product Contact | |
| ISI or HISA: | ISI |
| Link to Information Product: | |
| IC: | NIEHS |
| IC Division, Office, or Program: | Division of the National Toxicology Program |
| NIH Contact: | Sheena
Scruggs 984-287-3355 [email protected] |
| Reviewer Names and Expertise: | |
| Review Description: | External scientists will peer review the draft report via letter. |
| Date of Review: | 2021-05-01 |
| Number of Reviewers: | 2-3 |
| Reviewer Nominations Requested? | |
| Upcoming Panels, Events: | View Upcoming Panels, Events, Notices, Meeting Updates |
| Technical/Draft Reports, Public Comments and Presentations: | https://ntp.niehs.nih.gov/events/panels/index.cfm |
| Past Roster, Notices, Meeting Updates: | View Past Roster, Notices, Meeting Updates |
| Reviewer Expertise: | pathology, general tox, reproductive/developmental biology |
| How Selected: | NTP selected from identified experts |
| Opportunity for Public Comment? | YES |
| Did any reviewers require any exception to the applicable independence or COI standards of the Bulletin, including determination by the Sec./Dep. Sec. pursuant to Section (3)(c)? | |
| Were any waivers, deferrals, exemptions, or alterative peer review processes used? | |
| Any Public Meetings? | |
| Number of Public Comments Received | |
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