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Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB)
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Committee, Work group, Advisory group, or Task Force
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ASPR
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NIAID
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In March 2015, the Department of Health and Human Services (HHS) announced the establishment of the Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB). This Federal Advisory Committee (FACA) includes public voting members, non-voting liaison representatives from organizations and/or interest groups, and non-voting federal ex-officio members. PACCARB provides advice, information, and recommendations to the Secretary regarding programs and policies intended to support and evaluate the implementation of Executive Order 13676, including the National Strategy for CARB and the National Action Plan for CARB. PACCARB has been reauthorized until Jan 18, 2019 (based on its charter), through Executive Order 13811 on Sept. 29, 2017.
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Prevention Research Coordinating Committee (PRCC)
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Committee, Work group, Advisory group, or Task Force
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AHRQ, CDC, OS, FDA, OASH
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ODP, CC, FIC, NCATS, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, OD/DPCPSI/OAR, OD/DPCPSI/OBSSR, OD/DPCPSI/ORWH, OD/DPCPSI/ODS, OD/OLPA
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The NIH Prevention Research Coordinating Committee (PRCC) serves as a venue for exchanging information on recent scientific advances in disease prevention; examining the impact of new policies on research; planning new or discussing ongoing initiatives; and highlighting program accomplishments. As a trans-NIH, trans-agency committee, the PRCC provides a broad perspective on the current state-of-the-science and actively disseminates information about prevention-related activities sponsored by federal and non-federal organizations to the NIH Institutes and Centers.
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Probiotic and Prebiotic Working Group [PPWG] (PPWG)
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Committee, Work group, Advisory group, or Task Force
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FDA
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NCI, NCCIH, NIAMS, NIDA, NIDCR, OD/DPCPSI/ODS, CC, CIT, CSR, FIC, NCATS, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIBIB, NICHD, NIDCD, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, OEDI
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The Probiotic and Prebiotic Working Group (PPWG) is a trans-National Institutes of Health (NIH) effort formed in 2006 to identify gaps and challenges in prebiotic and probiotic research. Their goals include (1) facilitating interactions and collaborations among research scientists in the field of probiotics and prebiotics, (2) advancing prebiotic and probiotic research, and (3) understanding the role of gut microbiota and use of prebiotics and probiotics in health and disease. The working group strives to promote constructive interactions across NIH Institutes, Centers, and Offices, by disseminating real-time information and keeping PPWG members abreast of current and future activities occurring in the fields of probiotics and prebiotics. The group meets quarterly to form allied partnerships and collaborate on various pre- and probiotic activities. Two trans-NIH Program Announcements were released in 2015 and were renewed in 2018 (PA-18-902; PA-18-876 ).
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Promoting Semantic Interoperability of Laboratory Data Test Results
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Resource Development
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CDC, FDA
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NLM
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The Centers for Disease Control and Prevention (CDC) and the National Library of Medicine (NLM) encourage considering ways that the Food and Drug Administration (FDA) could accelerate specifications of LOINC codes that apply to each test result that a lab/test instrument or kit can generate. Availability of the right LOINC codes with each instrument test kit will greatly simplify the correct assignment of codes by a laboratory for sending to clinician's medical record system.
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Public Health and Emergency Medical Countermeasures Enterprise (PHEMCE)
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Committee, Work group, Advisory group, or Task Force
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ACF, CDC, FDA, OS, SAMHSA
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NIAID, NIAMS, NICHD, NINDS, NLM
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The Public Health and Emergency Medical Countermeasures Enterprise (PHEMCE) advances national preparedness for natural, accidental, and intentional threats by coordinating medical countermeasure-related efforts within HHS and in cooperation with PHEMCE interagency partners. NIAID has representatives on many groups within PHEMCE.
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Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) Preparedness Against Chemical Threats (PACT) Working Group (PHEMCE PACT Working Group)
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, OS
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NINDS, NIAID
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The US Department of Health and Human Services (HHS) Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) leads the mission to develop and acquire medical countermeasures that will improve public health emergency preparedness as well as prevent and mitigate the adverse health consequences associated with chemical, biological, radiological and nuclear (CBRN), and naturally occurring threats.
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Public Health Service Technology Transfer Policy Board (TTPB)
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA
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OD/OIR
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The purpose of the Public Health Service (PHS) Technology Transfer Policy Board (TTPB) is to serve as the principal advisory board for establishing PHS technology transfer policies and modifying existing policies, as applicable.; Membership is drawn from the National Institutes of Health (NIH) as lead agency in the PHS technology transfer program, the Centers for Disease Control and Prevention (CDC), and the Food and Drug Administration (FDA).
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Quantitative Data Mining for Drug-Adverse Event Safety Signal Detection Using MEDLINE
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Research Initiative
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FDA
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NLM
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The objective of this initiative between the National Library of Medicine (NLM) Cognitive Science Branch and the Center for Drug Evaluation and Research at the US Food and Drug Administration (FDA) is to develop a mutually beneficial automated data mining analytical tool in which NLM’s electronic databases and resources (including MEDLINE) are utilized to support the FDA’s mission related to enhancing postmarket drug safety surveillance and safe use.
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Quantum Barcoding for analysis of Ebola infection
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Resource Development
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FDA
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NIAID
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Viral MIBI and Quantum barcoding: These projects are part of an Food and Drug Administration (FDA) contract with Dr. Gary Nolan's group at Stanford. The first project will develop and validate an assay for nucleic acid-based method for viral detection on the MIBI, compatible with Formalin-Fixed Paraffin-Embedded tissue, and then apply to Ebola samples. The second will use quantum barcoding to develop anti-human and anti-macaque antibody reagents, to hep develop a system that will replace multiplexing technologies such as high parameter FACS and CyTOF with a platform based on sequence tags (rather than fluorophores or mass tags) that uses decontaminated and ambient temperature-stable samples. This will be applied to BSL-3/4 samples.
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Racial and Ethnic Disparities in Excess Deaths During the COVID-19 Pandemic
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Research Initiative
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CDC
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NCI, NIMHD
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Although racial/ethnic disparities in U.S. COVID-19 death rates are striking, focusing on COVID-19 deaths alone may underestimate the true effect of the pandemic on disparities. Excess death estimates capture deaths both directly and indirectly caused by COVID-19.xcess deaths and excess deaths per 100 000 persons from March to December 2020 were estimated by race/ethnicity, sex, age group, and cause of death, using provisional death certificate data from the Centers for Disease Control and Prevention (CDC) and U.S. Census Bureau population estimates.
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