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Computational Toxicology for NIH Medications Discovery
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Research Initiative
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FDA
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NIDA
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Through an inter-agency agreement, the Food and Drug Administration (FDA) provides structure-activity, relationship-based toxicity predictions for compounds that are under evaluation in the National Institute on Drug Abuse (NIDA) Addiction Treatment Discovery Program. On a limited basis, other National Institutes of Health (NIH) ICs may utilize this resource by working through NIDA.
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Computer-aided Diagnosis for Radiology Images
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Research Initiative
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FDA
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CC
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This collaboration focuses on the improvement of computer-aided diagnosis for radiology images. Specific applications include computer-aided polyp detection for computed tomography (CT )colonography, improvements in the conduct and analysis of observer performance experiments using radiology images, and the use and development of advanced machine learning and receiver operating characteristics methods with application to computer-aided diagnosis.
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Congenital Heart Public Health Consortium
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Resource Development
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AHRQ, CDC
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NHLBI
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The Congenital Heart Public Health Consortium (CHPHC) is a group of organizations uniting resources and efforts in public health activities. The mission of the CHPHC is to prevent congenital heart defects and improve outcomes for affected children and adults. The consortium achieves its mission by providing leadership and a unified voice for public health priorities, expanding opportunities for surveillance and public health research, and informing public policy priorities that benefit public health and affected persons. The CHPHC represents various federal, state, and community organizations, including those representing patient/family, clinical, and research interests. It is pooling expertise and experience and using a public health model to address Congenital Heart Disease (CHD) issues across the lifespan.
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Consumer Product Chemical Exposures in Pregnancy and Their Cumulative Impact on Disorders of Fetal Growth
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Research Initiative
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CDC
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NIEHS
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The purpose of this collaboration is to characterize exposure to organophosphate (OP) flame retardants and pesticides among pregnant women by measuring OP flame retardants and dialkyl phosphate metabolites (DAPs) in urine samples from 3 visits in pregnancy. We will examine associations between these markers and fetal growth as well as inflammation biomarkers.
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Contract to fund Congressional mandated National Academies of Sciences, Engineering, and Medicine (NASEM) study on Organ Donation and Transplantation
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Committee, Work group, Advisory group, or Task Force
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HRSA
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NIAID, NHLBI, NIDDK
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Contract for a NASEM study to examine and recommend improvements to research, policies, and activities related to organ donation and transplantation. The report shall include: ( 1) identification of current challenges involved in modeling proposed organ allocation policy changes and recommendations to improve modeling; (2) recommendations about how costs should be factored into the modeling of organ allocation policy changes; (3) a review of scoring systems (e.g., CPRA, EPTS, KDPI, LAS, MELD, etc.) or other factors that determine organ allocation and patient prioritization and recommendations to assure fair and equitable practices are established, including reducing inequities affecting socioeconomically disadvantaged patient populations; ( 4) recommendations to update the OPTN's policies and processes to ensure that organ allocation decisions take into account the viewpoints of expert OPTN committees; and (5) such other issues as may be identified.
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COPD National Action Plan
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Meeting/ Workshop
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AHRQ, CDC, CMS, HRSA, IHS
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NHLBI, NCI, NIA, NIEHS, NINR
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The Chronic Obstructive Pulmonary Disease (COPD) National Action Plan is the first-ever blueprint for a multi-faceted, unified fight against the disease. Developed at the request of Congress with input from the broad COPD community, it provides a comprehensive framework for action by those affected by the disease and those who care about reducing its burden.
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Council on Emergency Medical Care (CEMC)
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Committee, Work group, Advisory group, or Task Force
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AHRQ, CDC, CMS, HRSA, OS, SAMHSA
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NIMH, NCATS, NHLBI, NICHD, NIGMS, NINDS, NLM
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The Council on Emergency Medical Care (CEMC) is a coalition comprised of subject-matter experts and policymakers in emergency medical care from organizations across the Federal Government. The CEMC contributes to the development, advancement, and coordination of federal strategies, policies, and priorities relating to emergency medical care to improve the nation’s emergency care system.
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Countering Biothreats IPC on Promoting and Protecting the Bioeconomy
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Committee, Work group, Advisory group, or Task Force
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FDA, OS
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OD/OSP
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Discusses and coordinates policy options related to promoting and protecting the bioeconomy.
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Countering Biothreats sub-IPC on Promoting and Protecting the Bioeconomy
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Committee, Work group, Advisory group, or Task Force
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FDA, OS
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OD/OSP
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Discusses and coordinates policy options related to promoting and protecting the bioeconomy; Sub-Committee of the Countering Biothreats PCC on Promoting and Protecting the Bioeconomy.
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Countermeasures Against Chemical Threats (CounterACT) Research Network (CounterACT Research Network)
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Research Initiative
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CDC, FDA, OS
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NINDS, NEI, NIAID, NIAMS, NICHD, NIEHS, NIGMS, NLM
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The CounterACT program is a translational research program supporting basic, translational, and clinical research aimed at the discovery and identification of better therapeutic medical countermeasures and diagnostic technologies against chemical threat agents, which facilitates their movement through the regulatory process in collaboration with other federal departments and agencies, such as the Biomedical Advanced Research and Development Authority (HHS BARDA). The program includes a comprehensive network of Research Centers of Excellence, individual co-operative research projects, small business innovation research grants, contracts, and interagency agreements with the Department of Defense. Among other activities, the National Institute of Neurological Disorders and Stroke (NINDS) organizes an annual meeting of investigators supported by the program allowing researchers to share information, encourage collaboration, and enable the National Institutes of Health (NIH) staff to evaluate the group’s progress on themes such as nerve agents, seizure detection technology, cyanide, and sulfur mustard.
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