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Action for Health in Diabetes (Look AHEAD)
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Research Initiative
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CDC, IHS
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NIDDK, NIA
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The Action for Health in Diabetes (Look AHEAD) is a randomized trial comparing the effects of Intensive Lifestyle Intervention (ILI) focused on weight loss achieved through healthy eating and increased physical activity versus a control condition of Diabetes Support and Education (DSE) in overweight and obese individuals with type 2 diabetes. The Look AHEAD Extension (LA-E) will examine whether ILI, provided for 10 years during mid-life, has enduring benefits that persist beyond the period of the intervention for older individuals with diabetes.
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Acute Flaccid Myelitis (AFM) Studies
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Research Initiative
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CDC
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NIAID, NICHD, NINDS
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This is a joint effort to find the cause of AFM by developing research initiatives as well as working group activities.
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Acute Flaccid Myelitis (AFM) Workshop Planning Committee
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Meeting/ Workshop
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CDC
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NICHD, NIAID, NINDS
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This workshop (planned for May 2020) will bring together research scientists, clinicians, patient advocacy groups, and representatives from relevant organizations to discuss the state-of-the-science for AFM and GBS. The meeting will highlight similarities between the two diseases and facilitate cross-pollination of ideas to advance research, diagnostics, and therapy development for both. Particularly for National Institute of Child Health and Human Development (NICHD), the gaps identified for diagnosis, treatment and management of AFM and it’s consequences in children would inform potential development of future initiatives to address these.
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Adjuvant Working Group
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Committee, Work group, Advisory group, or Task Force
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BARDA, FDA
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NIAID, NCI
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Staff from all National Institute of Allergy and Infectious Diseases (NIAID) Divisions, program staff from the Biomedical Advanced Research and Development Authority (BARDA), and regulatory staff from the Food and Drug Administration (FDA) exchange information about ongoing programs related to novel adjuvants for infectious disease vaccines, identify high priority research areas (and gap areas), and discuss ideas to accelerate progress in adjuvant research through better access to information and resources.
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Adolescent Brain Cognitive Development (ABCD) Study
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Research Initiative
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CDC
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NIDA, NCI, NIAAA, NICHD, NIMH, NIMHD, NINDS, OD/DPCPSI/OBSSR
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The Adolescent Brain Cognitive Development (ABCD) project, a landmark longitudinal study of brain development and child health, will increase our understanding of how diverse experiences during adolescence interact with changing biology to influence brain, cognitive, and social/emotional development of youth. In partnership with area public and private schools, researchers at twenty-one research sites across the country will recruit 10,000 children at age 9-10 from diverse races and ethnicities, education and income levels, and living environments and follow them through their teens and into early adulthood. Throughout this period, researchers will assess each child’s physical and mental health, substance use, sleep patterns, genetics, childhood experiences, and cultural/environmental influences, as well as track brain and cognitive development with non-invasive magnetic resonance imaging scans at regular intervals. To enrich the value of the study, ABCD will release anonymized data annually to the research community in an open science model to allow scientists from all over the world to conduct analyses and pool resources to rapidly expand the types of scientific questions that can be answered. The actionable information coming out of this study will enable education, substance use prevention, and other health promotion policies to ensure the wellbeing and success of the Nation’s children.
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Adolescent Health Working Group
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Committee, Work group, Advisory group, or Task Force
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ACF, AHRQ, CDC, CMS, FDA, HRSA, OS, SAMHSA
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NICHD, NIAAA, NIDA, NIMH
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This interagency working group, which was established in January 2010 within the Office of the Assistant Secretary for Health, provides a forum for Department of Health and Human Services (HHS) agencies and other federal agencies to learn from each other and support a full-range of evidence-based approaches to improve adolescent health, to address adolescents’ health risks, and highlight programs focused on positive youth development. This collaboration among many HHS agencies and offices serves as a forum for exchanging information relevant to improving adolescent health and well-being
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Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA)
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Committee, Work group, Advisory group, or Task Force
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CDC, OS
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NICHD, FIC, NIAID, NIMH, OD/DPCPSI/OAR
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The Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA) aims to enhance the effective use of evidence and help overcome implementation challenges related to prevention, screening and treatment of HIV among adolescents (ages 15 to 24) in sub-Saharan Africa by catalyzing collaboration and communication among implementation scientists, program implementers and policymakers. The Center for Global Health Studies at Fogarty is launching the initiative in collaboration with the Office of the Global AIDS Coordinator and other NIH Institutes and Centers.
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Adolescent Human Immunodeficiency Virus (HIV) Prevention and Treatment Implementation Science Alliance (AHISA)
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Committee, Work group, Advisory group, or Task Force
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CDC
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FIC, NIAID, NICHD, NIMH, OD/DPCPSI/OAR
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The Adolescent Human Immunodeficiency Vrus(HIV) Prevention and Treatment Implementation Science Alliance (AHISA) aims to enhance the effective use of evidence and help overcome implementation challenges related to prevention, screening, and treatment of HIV among adolescents (ages 15 to 24) in sub-Saharan Africa by catalyzing collaboration and communication among implementation scientists, program implementers, and policymakers. The goals of the Alliance are to: 1) provide a platform for cross-fertilization and exchange of ideas and information among implementation scientists and other stakeholders focusing on different aspects of HIV in adolescents; 2) enable the research to be better informed by programmatic challenges and questions; 3) inform policymakers of promising evidence and encourage use of the data in decision making; and 4) extend the reach and impact of implementation science related to adolescent HIV prevention and treatment.
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Adolescent Medication-Assisted Treatment and Opioids Committee
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Committee, Work group, Advisory group, or Task Force
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OS, SAMHSA
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NICHD, NIDA
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The goal of this committee is to provide federal agencies with a better understanding of adolescent medication-assisted treatment (MAT) policy, research, and practice and to inform future initiatives.
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Advanced Anticonvulsant System Interagency Product Team
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Committee, Work group, Advisory group, or Task Force
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FDA, OS
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NINDS
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The Advanced Anticonvulsant System Interagency Product Team is a Department of Defense-led effort to facilitate activities, both research and regulatory, related to the FDA approval of midazolam for use in treating nerve agent exposure.
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