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The Epidemiology of Burkitt Lymphoma in East-African Children and Minors (EMBLEM)
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Research Initiative
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CDC
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NCI
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The Epidemiology of Burkitt Lymphoma in East-African Children and Minors (EMBLEM) initiative provides a unique infrastructure to obtain valuable data and samples to study Burkitt’s lymphoma (BL) epidemiology. Study data will help characterize or investigate: (1) The association of malaria-resistance genes with endemic BL. (2) Host genetic polymorphisms associated with BL using genome-wide association methods. (3) The role of the Epstein-Barr virus (EBV) genetic variants in endemic BL. (4) The role of malaria immunology and phenotype of inflammation in BL. (5) The complexity of coinfection with different P. falciparum malaria genotypes in BL. (6) The interaction between helminthic parasites, HIV, malaria, and EBV in BL. (7) The immunohistochemistry and molecular pathology of BL. (8) The impact of malaria, helminthic parasites, and HIV on childhood BL.
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The Federal Tuberculosis Task Force
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Committee, Work group, Advisory group, or Task Force
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AHRQ, CDC, FDA, HRSA, IHS, OS
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NIAID, NICHD
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The Federal Tuberculosis (TB) Task Force is a coalition composed of the Federal agencies and organizations involved in US TB control efforts. Established in 1991, the Task Force facilitates coordination of activities between Federal agencies. It was created by the Director of the Centers for Disease Control and Prevention (CDC) to address the outbreaks of multidrug-resistant (MDR) TB occurring during the 1985-1992 surge in TB cases. The TB Task Force is co-chaired by CDC and NIAID.
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The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study
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Research Initiative
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CDC
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NIDDK, NHLBI
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The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) is a long-term study of different treatments for type 2 diabetes. A major challenge in diabetes treatment is to determine which of the many possible drugs is the best choice among people already treated with metformin, the most commonly used diabetes drug. GRADE is a randomized clinical trial of participants diagnosed with type 2 diabetes within the past 10 years who are already on metformin. Participants will be randomly assigned to one of four commonly-used glucose-lowering drugs (glimepiride, sitagliptin, liraglutide, and basal insulin glargine), plus metformin, and will be followed for up to 7 years. The goal of the GRADE Study is to determine which combination of two diabetes medications is best for achieving good glycemic control, has the fewest side effects, and is the most beneficial for overall health in long-term treatment for people with type 2 diabetes.
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The Healthy Brain Initiative
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Public Education Campaign
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ACL, CDC
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NIA
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The Healthy Brain Initiative, or Roadmap, is a project of the Centers for Disease Control and Prevention (CDC) and the Alzheimer''s Association. NIA, along with other HHS participation and a representative from the Administration for Community Living/Administration on Aging, help refine recommendations for state and local governments, with use of Federal resources, to address brain health/dementia in communities.
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The Impact of Tobacco Use on Oral Health and the Oral Microbiome
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Research Initiative
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CDC, FDA
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NCI
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The US Food and Drug Administration Intramural Center of Tobacco Regulatory Science Award Program funded a project examining how tobacco affects oral health and the oral microbiome in the National Health and Nutrition Examination Survey (NHANES) study.
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The Incidence of Breast and Other Cancers Among Female Flight Attendants
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Research Initiative
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CDC
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NCI
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A cohort study of approximately 10,000 Pan Am flight attendants to determine cancer incidence (primarily breast cancer) associated with cosmic radiation and circadian disruption from their work.
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The Interagency Committee on Human Nutrition Research (ICHNR)
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, HRSA
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NIDDK
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The Interagency Committee on Human Nutrition Research (ICHRN) is charged with improving the planning, coordination, and communication among federal agencies engaged in nutrition research.
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The Interagency Committee on Human Nutrition Research (ICHNR) Dietary Guidelines Subcommittee
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, OS
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NICHD, NIDDK, OD/DPCPSI/ODS
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The Interagency Committee on Human Nutrition Research (ICHNR) dietary guidelines subcommittee serves to improve planning, coordination, and communication among federal agencies engaged in research in nutrition and/or nutrition policies, surveillance, technologies, and related issues. The key focus of the Subcommittee on Dietary Guidelines is to gain perspectives from Federal stakeholders regarding the Dietary Guidelines Advisory Committee''s (DGAC) deliberations and identify any gaps or concerns that are important to Federal programs and to engage USDA and HHS agencies in the DGA policy development process.
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The MDEpiNet TMJ RoundTable
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Meeting/ Workshop
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AHRQ, FDA
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NIDCR
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This workshop facilitated collaboration of stakeholders to address data on implant performance, surgical outcomes, and adverse events in an effort to: develop outcome and assessment and reporting tools based on patient input, the intersection of patient biology, anatomy, genetics, physiology with TMJ medical devices, and clinical patient-centered outcomes to better target therapies.
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The Mental Health Block Grant Ten Percent Set Aside (MHBG) Evaluation
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Other
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SAMHSA
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NIMH
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The Substance Abuse and Mental Health Services Administration (SAMHSA) is sponsoring an evaluation of first episode psychosis treatment programs funded through the federal 10 percent Mental Health Block Grant Set Aside. Through an inter-agency agreement, the National Institute of Mental Health (NIMH) is co-funding the evaluation and is actively involved in all phases of the evaluation design and planning.
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