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CDC/HRSA Advisory Committee on HIV, Viral Hepatitis, and STD Prevention and Treatment (CHACHSPT)
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Committee, Work group, Advisory group, or Task Force
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CDC, CMS, FDA, HRSA, IHS, OS, SAMHSA
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OD/DPCPSI/OAR
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The CDC / HRSA Advisory Committee on HIV, Viral Hepatitis and STD Prevention and Treatment shall advise the Secretary; the Director, CDC; and the Administrator and Associate Administrator for HIV/AIDS, HRSA, regarding objectives, strategies, policies, and priorities for HIV and STD/hepatitis prevention and treatment efforts including surveillance of HIV infection, AIDS, STDs/hepatitis, and related behaviors; epidemiologic, behavioral, health services, and laboratory research on HIV/AIDS and STDs/hepatitis; identification of policy issues related to HIV/STD/hepatitis professional education, patient healthcare delivery, and prevention services; agency policies about prevention of HIV/AIDS and other STDs, treatment, healthcare delivery, and research and training; strategic issues influencing the ability of CDC and HRSA to fulfill their missions of providing prevention and treatment services; programmatic efforts to prevent and treat HIV and STDs/hepatitis; and support to the agencies in their development of responses to emerging health needs related to HIV and other STDs/hepatitis.
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CDC/NCHS Balance/Dizziness Problems
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Health Survey
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CDC
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NIDCD
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The purpose of this agreement is for NIDCD to provide financial support to the National Center for Health Statistics (NCHS) for the inclusion of a Balance/Dizziness Supplement to a future National Health Interview Survey (NHIS). Previously, NIDCD negotiated an Interagency Agreement (IAA) with NCHS for collaboration and funding of the 2008 Balance/Dizziness Supplement to the NHIS. The FY2013 funds will provide partial support for the renewal of this collaborative effort between NCHS and NIDCD to fund a future Balance/Dizziness Supplement to the NHIS. The new NHIS Supplement will include many of the same questions on Balance/Dizziness included in the earlier 2008 study, although revisions are expected to eliminate some questions in order to consider adding new ones high on the current priority list. These questions on the new Balance/Dizziness Supplement will assist NIDCD to make program planning decisions on priorities with respect to the funding of research on the prevention of falls related to dizziness and balance. The results will also be analyzed for use in tracking the Department of Health and Human Services’ (DHHS) objectives in Healthy People 2020. Results from this nationally-representative survey of the U.S. non-institutionalized, civilian population will help NIDCD make budget allocations to subject areas where needs are found to be most critical.
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CDC/NIOSH for Audiometric Support for 3 NIDCD-Sponsored, Population-Based Surveys
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Health Survey
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CDC
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NIDCD
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The purpose of this agreement is to provide funding for scientific and technical support as well as quality assurance of three large audiometric examination surveys funded by NIDCD. These health surveys are: (i) The National Health and Nutrition Examination Survey (NHANES), (ii) Age, Gene/Environment Susceptibility Study–Reykjavik Study (AGES–RS), and (iii) the Early Childhood Longitudinal Study – Kindergarten Class of 2010/2011 (ECLS–K:2010/2011). The Audiometry Components of all three health examination surveys were previously developed by NIDCD in collaboration with NIOSH and other consultants. NIOSH collaborated on the design of the experimental protocol and provided the equipment specifications, oversight of maintenance and calibration, technician training and oversight, operations manual development, and quality assurance for the NHANES. As well, NIOSH provided similar support to AGES and ECLS–K:2010/2011, including setting-up training sessions and observing/monitoring technical competence in obtaining audiometric measurements, technical assistance as needed, and limited quality assurance. The NHANES scientific goals are to establish a statistically accurate, demographically representative baseline on the general health (including Hearing Health) of the U.S. population. NHANES is now a continuous survey and while general health issues are always under investigation such as height, weight and blood pressure, there are also elements that track individual health outcomes that move in and out of the NHANES as it cycles. NHANES consists of two major components: the household interview and the physical examination in the NHANES Mobile Examination Centers (MECs) that are set up in various areas around the country. The data from the NHANES elements are collected, weighted, and made available to the government and the public as a database on which analysis may be performed. Recently, the data have been released every two years with collaborating agencies receiving the data six months prior to the public release of the data sets. The AGES–RS scientific goals are: 1) to identify genetic and new risk factors for selected diseases including atherosclerosis, cognitive impairment, dementia, stroke, hearing loss, visual impairment, sarcopenia, osteoporosis, and obesity, 2) to characterize phenotypes for these diseases and conditions, and 3) to identify contributory molecular markers associated with these conditions. The proposed ECLS:K-2011 audiometry protocol for the third-grade data collection includes four components: pre-test questions, otoscopy, wideband reflectometry with tympanometry, and pure tone audiometry. (1) Pre-Test Questions: Children will be asked a series of short questions regarding conditions which could affect the test results (cold or earaches, noise exposure within past 24 hours, presence of pe tubes, and whether one ear is better than the other); (2) Otoscopy: Children will receive a brief visual examination of the ear, primarily to assure a clear sound path. In addition, the technicians will note the presence of excessive cerumen or any other gross abnormality which could affect interpretation of audiometric findings. The otoscopic exam will not be diagnostic; it will simply be observational; (3) Wideband Reflectometry, including Tympanometry: An automated wideband reflectometric/tympanometric evaluation of the middle ear will be conducted bilaterally. Analysis and interpretation of the results will be done remotely; (4) Pure Tone Audiometry: Pure tone air conduction thresholds will be obtained bilaterally at 1000, 2000, 3000, 4000, 6000, and 8000 Hz insofar as time and the child’s attention permits. A retest threshold will be obtained in both ears at 2000 Hz as a measure of test reliability. The thresholds will be obtained manually using a modified Hughson-Westlake technique. The first test ear will be alternated to avoid learning effect bias in the thresholds. Frequencies will be tested in a specified order to obtain the more important frequency data first in case time or the child’s attention runs out before all frequencies are completed. All three health surveys share similar hearing exam components, developed collaboratively by NIDCD, NIOSH, NCHS, WESTAT, the Icelandic Heart Association Research Institute, and the Department of Education, National Center for Education Statistics. The hearing component consists of: 1) a set of questionnaires relating to hearing, noise exposure, and other factors relating to hearing, and 2) audiometric examinations consisting of otoscopy, acoustic immittance (bilateral tympanometry or wide-band reflectometry and screening for ipsilateral acoustic reflexes at 1000 and 2000 Hz), and 3) pure-tone, air-conduction audiometry to determine the hearing thresholds in each ear at several frequencies, such as 500, 1000, 2000, 3000, 4000, 6000, and 8000 Hz. A repeat threshold test is obtained at 1000 Hz or 2000 Hz as a measure of test reliability. When significant inter-ear differences are found, then retests may be performed using insert earphones to maximize the inter-aural attenuation rather than using a noise masker of the non-test ear to obtain what is referred to as masked threshold in the test ear to avoid recording of a “shadow audiogram” from the better non-test ear.
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CDC’s Field Epidemiology Training Program (FELP) Cancer Curriculum
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Training Initiative
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CDC
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NCI
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CDC and NCI (Center for Global Health and Cancer Prevention Fellowship Program) are collaborating to add a cancer curriculum to CDC’s Field Epidemiology Training Program.
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Cell Therapy for Lung Diseases
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Meeting/ Workshop
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FDA
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NHLBI
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Acute and chronic lung diseases are leading causes of morbidity, mortality, and health care expenditures. Innovative approaches for therapies are urgently needed. Increasingly, patients who suffer from chronic lung diseases are seeking stem cell therapies outside the U.S. due to limited opportunities to participate in clinical studies of stem cells in the U.S. The current NHLBI portfolio on lung stem and progenitor cells has focused primarily on basic research to build fundamental knowledge of the role of stem/progenitor cells in lung disease and injury/repair. However, clinical application of cell therapy for lung diseases will require a more focused approach that coordinates basic research with translational research to facilitate cell-based clinical trials.
Therefore, the NHLBI convened a Cell Therapy for Lung Diseases working group on November 13-14, 2012 to make recommendations for future research directions. The workshop brought together investigators who study basic mechanisms including cell therapy in preclinical models of lung injury/disease along with clinical trial experts in cell therapy for cardiovascular indications and experts from NHLBI’s Production Assistance for Cell Therapy (PACT) program.
The overall objective was to discuss the current status of basic investigations in lung cell therapy, identify the scientific gaps in current knowledge regarding cell therapy in the treatment of lung diseases, and develop recommendations to the NHLBI and the research community on scientific priorities that would facilitate high quality, rigorous first-in-human trials of lung cell therapy.
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Characterizations of Fungal Exposures
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Research Initiative
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CDC
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NIEHS
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These studies address the limitations in traditional methods for assessing fungal exposures by using molecular techniques to identify fungi in dust samples and biological fluids
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Chemical Integrated Program Team (IPT)
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, OS
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NICHD
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This workgroup is a Public Health Energy Enterprise. The IPT working group provides an end-to-end vision of medical countermeasures needed for a particular threat type (e.g., anthrax, rad/nuc, etc.). The scope of their work includes setting requirements for the stockpiling of Medical Countermeasures (MCMs), MCM delivery and dispensing and monitoring MCM development. The IPTs also advise the Enterprise Executive Committee as to threat- or capability-specific MCM priorities for improving preparedness, to inform leadership consideration of cross-threat prioritizations and strategic goal setting.
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CHEMM (Chemical Hazards Emergency Medical Management)
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Resource Development
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ATSDR, CDC, OS
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NLM
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This activity is to develop and maintain a comprehensive web resource and mobile app (in conjunction with the Wireless Information System for Emergency Responders [WISER]). Chemical Hazards Emergency Medical Management (CHEMM) is a tool designed to provide access to comprehensive sets of information about chemical hazards via a user-friendly interface.
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Child Abuse and Neglect Working Group (CANWG)
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Committee, Work group, Advisory group, or Task Force
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ACF, HRSA, SAMHSA
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NICHD, CSR, NIAAA, NIDA, NIMH, NINDS, OD/DPCPSI/OBSSR
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The NIH Child Abuse and Neglect Working Group (CANWG) was established in response to a recent directive by the House Committee on Appropriations, which requested that NIH report on current NIH efforts, accomplishments, and future plans for research on child abuse and neglect. The CANWG is co-chaired by program staff from NICHD and NIDA (formally NIMH). The working group is also a subcommittee of the Federal Interagency Workgroup on Child Abuse and Neglect.
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Children''s HHS Interagency Leadership on Disasters (CHILD) Working Group
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Committee, Work group, Advisory group, or Task Force
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OS
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NICHD
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The purpose of this workgroup is to document HHS''s steps taken and provide recommendation for next steps regarding the care of children and pregnant women in the event of a disaster.
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