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Intragovernmental Select Agents and Toxins Technical Advisory Committee (ISATTAC)
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA, OS
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OD/OSP, NIAID
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The ISATTAC is a working group of subject matter experts from the Federal Government formed by the CDC Director to provide recommendations to the CDC''s Division of Select Agents and Toxins in three technical areas: 1) review requests for exclusion of attenuated strains, 2) review requests to conduct restricted experiments, and 3) review of select agents and toxins. The Committee conducts a biannual review, required by the Select Agent Rule of the Select Agents and Toxins list for HHS. Expert input from the ISATTAC and public comments are the primary inputs into this process.
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Investigations into Health Effects Caused by Exposure to Indoor Air Reaction Products
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Research Initiative
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CDC
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NIEHS
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Ongoing studies are identifying and quantifying the volatile reaction products of gas-phase compounds present in the indoor environment, especially dicarbonyls, and investigating immunotoxic and hypersensitivity effects of these reaction products in both in vitro and in vivo models.
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Investigations of Early Life Determinants of Pediatric and Adult Malignancies in a Population
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Research Initiative
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CDC
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NCI
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In collaboration with investigators from the U.S. CDC and the China CDC, NCI is assessing risk of pediatric leukemia and other pediatric cancers in a large population of offspring of mothers enrolled in a community intervention program of peri-conception folic acid supplementation in China. Pediatric cancer risks will be compared in offspring of mothers treated vs offspring of mothers not treated with folic acid supplements.
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Iron and Malaria Research Project
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Research Initiative
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CDC, OS
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NICHD, NIAID
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In November 2007, the NICHD launched the Iron and Malaria Project to identify and examine factors that affect the safety and effectiveness of interventions to prevent iron deficiency in the context of malaria and other infections. The Project is funded, in part, by the Bill and Melinda Gates Foundation with additional support from the NIH Office of Dietary Supplements. The Project aims not only to generate new data to address this high-priority global health issue, but also to support efforts of the World Health Organization (WHO) to develop evidence-based guidelines with specific regard to the use of iron interventions. The Project and its goals grew out of new research that examined historical concerns about the safety of iron supplementation and, in particular, evidence of an increased risk for poor health outcomes among those (primarily young children) who were not iron deficient, but who received iron supplementation as part of “universal” supplementation programs in regions where malaria and other infections are common. The objective of this meeting was to assess progress of the funded grants and discuss the research project. This project has 3 sub-projects with direct collaborations with CDC: Inflammation and nutrition science for programs/policy and interpretation of research evidence (INSPIRE); Soluble transferrin receptor (sTfr) standard material development project to help provide standards to evaluate reliability and validity of assays to measure sTfr, a biomarker of iron status - Biomarkers reflecting inflammation and nutritional determinants of anemia (BRINDA)
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Joint Committee and Joint Commission Meetings
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Meeting/ Workshop
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CDC, FDA, OS
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NCI, FIC, NIAID
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US State Department establishes collaborative agreements with foreign governments in fields of science and technology. These Joint Committee and Joint Commission Meetings (JCMs) facilitate discussion on selected topics creating cross-talk among the equivalent government agencies leading towards future collaborations. The OS through OGA organizes the DHHS OP/DIVs; FIC facilitates NIH ICs participation. For FY2011, JCMs were convened for Brazil, Colombia, and Mexico.
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Joint Fellowship Program
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Training Initiative
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FDA
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NCI
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The objective of the NCI-FDA fellowships is to train a cadre of scientists in research and research-related regulatory review, policies, and regulations so that they develop a skill set that bridge the two disparate processes. Fellows will learn to build awareness of regulatory requirements into the early stages of the medical product development process and develop strategies to improve planning throughout research and regulatory review.
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Kaposi Sarcoma and HHV8 in Sickle Cell and Other Ugandan Populations
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Research Initiative
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CDC
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NCI
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Epidemiological studies are being conducted to assess small-area variation of HHV8 and to learn about socio-demographical and environmental risk factors for HHV8 and Kaposi sarcoma in Uganda.
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Kidney Interagency Coordinating Committee (KICC)
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Committee, Work group, Advisory group, or Task Force
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AHRQ, CDC, CMS, FDA, HRSA, IHS
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NIDDK, NHLBI, NIA
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The goal of the Kidney Interagency Coordinating Committee (KICC) is to encourage cooperation, communication, and collaboration among all federal agencies involved in kidney research and other activities. The KICC Consists of Federal representatives involved in chronic kidney disease (CKD) programs. The National Kidney Disease Education Program (NKDEP) convenes KICC annually to share information on various agencies'' programs and activities related to CKD and to discuss ways to improve the coordination of Federal responses to CKD.
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Know Stroke in the Community
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Public Education Campaign
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CDC
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NINDS
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The NINDS developed the Know Stroke campaign to help educate the public about the symptoms of stroke and the importance of getting to the hospital quickly. The campaign includes outreach to consumers and health care professionals using mass media, grassroots outreach, partnerships, and community education.
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Leprosy Research Support and Maintenance of an Armadillo Colony
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Resource Development
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HRSA
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NIAID
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This interagency agreement helps to establish and maintain a colony of wild caught armadillos that are infected with M. leprae. Infected organs and tissues are used to develop and make available standardized research reagents to investigators worldwide. This project also includes studies to optimize infection of armadillos for maximum yield, early identification of animals that were successfully infected, and studies to assess the timecourse and location of infection to create additional samples for disease studies. The project also maintains the mouse footpad model and other methods to amplify M. leprae bacteria from human specimens before they can be used to infect armadillos.
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