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NTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnamate (CASRN 5466-77-3) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats with Prenatal, Reproductive...
| Document, Report, or Other Product Information | |
|---|---|
| Title: | NTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnamate (CASRN 5466-77-3) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats with Prenatal, Reproductive... |
| Subject: | NTP conducted a multigenerational study (modified one-generation; MOG) in rodents to assess the potential for continual exposure to 2-ethylhexyl p-methoxycinnamate (EHMC) via the diet to affect reproduction and development and induce subchronic toxicity. Full title: NTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnamate (CASRN 5466-77-3) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats with Prenatal, Reproductive Performance, and Subchronic Assessments in F1 Offspring |
| Purpose (e.g., abstract): | This peer review done via panel conducted in Q2 2021. It will assess of the draft NTP developmental and reproductive toxicity technical report (DART-06). Information for the review will be posted once dates are finalized. |
| Information Product Contact | |
| ISI or HISA: | ISI |
| Link to Information Product: | |
| IC: | NIEHS |
| IC Division, Office, or Program: | Division of the National Toxicology Program |
| NIH Contact: | Sheena
Scruggs 984-287-3355 [email protected] |
| Reviewer Names and Expertise: | |
| Review Description: | External scientists will peer review the draft report via letter. |
| Date of Review: | 2021-05-01 |
| Number of Reviewers: | 2-3 |
| Reviewer Nominations Requested? | |
| Upcoming Panels, Events: | View Upcoming Panels, Events, Notices, Meeting Updates |
| Technical/Draft Reports, Public Comments and Presentations: | https://ntp.niehs.nih.gov/events/panels/index.cfm |
| Past Roster, Notices, Meeting Updates: | View Past Roster, Notices, Meeting Updates |
| Reviewer Expertise: | pathology, general tox, reproductive/developmental biology |
| How Selected: | NTP selected from identified experts |
| Opportunity for Public Comment? | YES |
| Did any reviewers require any exception to the applicable independence or COI standards of the Bulletin, including determination by the Sec./Dep. Sec. pursuant to Section (3)(c)? | |
| Were any waivers, deferrals, exemptions, or alterative peer review processes used? | |
| Any Public Meetings? | |
| Number of Public Comments Received | |
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