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Dietary Supplement Relevant - Special Interest Databases (purines, nitrates/nitrates)
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Resource Development
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FDA
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OD/DPCPSI/ODS
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The National Institutes of Health's, Office of Dietary Supplement collaborates with the US Department of Agriculture's (USDA) Methods and Application of Food Composition Laboratory on the development of several special interest food composition databases, such as the USDA, FDA and ODS-NIH Database for the Iodine Content of Common Foods, the USDA Special Interest Databases on Flavonoids and more recently funding for the development of a database on nitrates/nitrites, thiocyanates, glucosinolates, and purines (including Methylxanthines). These databases allow researchers to estimate these components in their diet studies and provide information for clinicians/dietitians when providing dietary guidance.
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Dietary Supplement Research Coordination Committee (DSRCC)
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Committee, Work group, Advisory group, or Task Force
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CDC, FDA
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OD/DPCPSI/ODS, CC, FIC, NCATS, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NINR, NLM, OD/DPCPSI/OBSSR, OD/DPCPSI/ORWH, OD/DPCPSI/ONR
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The National Institutes of Health's, Office of Dietary Supplement Dietary Supplement Research Coordinating Committee (DSRCC) was established in 2022 by the Office of Dietary Supplements (ODS) to increase collaboration among NIH Institutes, Centers, and Offices and federal agency partners whose programs include work that focuses on dietary supplements and the intersection of dietary supplement, natural product, and nutrition research. The DSRCC provides research coordination through the exchange of programmatic and scientific information, collaborative planning, and the implementation of relevant activities and initiatives.
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Digestive Diseases Interagency Coordinating Committee (DDICC)
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Committee, Work group, Advisory group, or Task Force
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CDC, CMS, FDA
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NIDDK, NCI, NIBIB
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The Digestive Diseases Interagency Coordinating Committee, chaired by NIDDK, is charged with facilitating cooperation and collaboration in research efforts in digestive diseases among NIH Institutes and other relevant Federal health agencies to provide a structure for coordinated efforts to combat digestive diseases. The Committee also prepares reports on the status of digestive disease research funding as well as needs for future research in specific areas of digestive diseases. The Committee meets to encourage exchange of information among member organizations and develop common initiatives.
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Digital Quantitation of Plasma Cells in Marrow Biopsies
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Research Initiative
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FDA
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CC
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This project is a collaboration between the National Institutes of Health (NIH )Clinical Center and the Food and Drug Administration (FDA)that consists of developing software and establishing validations for the automated determination of marrow cellularity and enumeration of plasma cells identified by immunohistochemistry (IHC) using a CD138 antibody. This initial effort should serve as proof of principle for a broader plan to utilize IHC-based automated quantitation of different types of cells in bone marrow core biopsies for diagnosis, prognosis, and therapy monitoring of marrow disorders.
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Drug Development Interest Group
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Committee, Work group, Advisory group, or Task Force
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ASPR
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NIAID, FIC, NCI, NHLBI
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Share information about state of the art and challenges in drug development for infectious diseases
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Drug Induced Liver Injury Network (DILIN)
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Resource Development
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FDA
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NIDDK, NCI
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Both a prospective and retrospective database containing cases of drug-induced liver disease, the Drug-Induced Liver Injury Network (DILIN) is funded by a cooperative agreement and includes eight clinical centers and a central data coordinating center. Established by NIDDK, one of the goals of the DILIN is to establish a database of well-characterized cases of drug-induced liver injury along with serum, DNA, and tissue samples that will facilitate research on the mechanisms of hepatic injury due to drugs. Cases of liver injury due to herbal medications are also included. The DILIN will develop standardized definitions of drug-induced liver disease and standardization of scoring systems for causality. Employees of the Food and Drug Administration (FDA) serve as ad hoc members on the committee overseeing the network activities.
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EAGeR Trial - The Effects of Aspirin in Gestation and Reproduction Trial
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Research Initiative
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FDA
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NICHD
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EAGeR Trial - The Effects of Aspirin in Gestation and Reproduction Trial
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Early Hearing Detection and Intervention
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Meeting/ Workshop
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CDC, HRSA
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NIDCD
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This is Federal collaboration program involving the National Institute on Deafness and Other Communication Disorders (NIDCD), the Centers for Disease Control and Prevention (CDC), and the Health Resources and Services Administration (HRSA). NIDCD collaborates on early identification and diagnosis of hearing loss and intervention services for newborns and infants. HRSA funds awards to states and healthcare providers to screen newborns and young children for hearing loss. CDC funds states to develop data systems to track hearing loss. NIDCD also funds research grants to scientists throughout the US to study early hearing detection and intervention services. Regular (roughly quarterly) meetings with federal partners, currently organized and facilitated by HRSA.
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Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) Multisite with Coordinating Center
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Research Initiative
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HRSA
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NHLBI, NICHD, NIDDK, OD/DPCPSI/OBSSR
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To test the effectiveness of an implementation-ready intervention designed to promote cardiovascular health (CVH) and address CVH disparities in both mothers and children (0-5 yr.) who are of low socio-economic status (SES), or live in low-income underserved rural or urban communities, or in diverse geographic regions with high burden of cardiovascular disease (CVD) risk factors (obesity, hypertension, diabetes).
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Ebola Clinical Research Response in Democratic Republic of the Congo
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Research Initiative
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CDC, ASPR
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NIAID
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Multi-lateral collaborative partnerships including, but not limited to National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and host countries Ministries of Health. Research focus includes Ebola and other emerging and re-emerging infectious diseases. These programs are capable of rapidly mounting a clinical research response.
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