|
Models of Infectious Disease Agent Study (MIDAS)
|
Research Initiative
|
CDC
|
NIGMS, FIC, NIAID
|
Models of Infectious Disease Agent Study (MIDAS) is a collaboration of research and informatics groups to develop computational models of the interactions between infectious agents and their hosts, disease spread, prediction systems, and response strategies. The models will be useful to public health workers and researchers who want to better understand and respond to emerging infectious diseases. If a disease outbreak occurs, the MIDAS network may be called upon to develop specific models to aid in our understanding of the disease and its spread.
|
|
Modernizing the Infrastructure for Capturing Drug Death Data and Enhancing Research on Opioid Poisoning using Death Certificates
|
Resource Development
|
CDC
|
NLM
|
(1) Advising the National Center for Health Statistics (NCHS) on strategies to extract, categorize and map drug-related strings terms and phrases from death certificate records’ literal text to classification systems used by researchers. (2) Establishing mappings between information technology systems that assure classification standards are used with respect to clinical terminologies. (3) Developing natural language processing (NLP) programs that reduce manual processes in classifying new drug terms identified on death certificates.
|
|
Monthly Zika Vaccine Development Meeting
|
Resource Development
|
BARDA, FDA
|
NIAID
|
This working group is collaborating on development of assays and animal models for zika vaccines. Collaboration includes exchange of study data, study reports, and regulatory strategy for assay and model development and development of a regulatory package to support licensure of products through alternative pathways.
|
|
Multinational Influenza Seasonal Mortality Study (MISMS) Research
|
Research Initiative
|
FDA, OS
|
FIC, NHLBI, NIAID, NLM
|
The Multinational Influenza Seasonal Mortality Study (MISMS) was originally initiated to analyze national and global mortality patterns associated with influenza virus circulation. The focus of MISMS has since expanded to evaluate the interaction between the epidemiology, ecology, and evolutionary dynamics of influenza and other rapidly transmissible respiratory viruses, on natural selection, reassortment, migration, and antigenic change. Multinational and bilateral collaborations developed through MISMS collect, analyze, and disseminate research findings through scientific publications, training workshops, and communication tools for investigators and decision-makers. These research findings inform numerous national governments, multilateral organizations, and research stakeholders on interventions for both pandemic and seasonal influenza. To date, data have been acquired from more than 40 countries (representing ~3.2 billion people), resulting in over 220 publications.
|
|
Muscular Dystrophy Coordinating Committee (MDCC)
|
Committee, Work group, Advisory group, or Task Force
|
ACL, CDC, FDA, HRSA
|
NINDS, NHLBI, NIAMS, NICHD
|
This Federal Advisory Committee coordinates activities relevant to the various forms of muscular dystrophy across the National Institutes of Health (NIH) and other federal agencies. The committee also includes members from patient organizations. Strategic planning efforts by the coordinating committee led to the development of an Action Plan for the Muscular Dystrophies, which contains specific research objectives appropriate to the missions of all committee member agencies and organizations, and thus serves as a central focus for research coordination. The plan is available at the MDCC web site.
|
|
My Family Health Portrait
|
Resource Development
|
CDC
|
NHGRI, NCI
|
My Family Health Portrait (MFHP) is a web-based tool from the National Human Genome Research Institute (NHGRI) and the US Surgeon General’s Family History Initiative that helps individuals track their family health history. Using any computer, an Internet connection, and an up-to-date Web browser, individuals add health information to build a drawing of their family tree and a chart of their family health history while exploring disease calculators. The tool is designed to keep all data on the client side to maximize privacy using HTML, CSS, and client-side JavaScript as its principal platforms. Users interact with the tool in a browser to build family health history generating an XML data file (HL7v3 standard) that users store locally or in the cloud. Both the family tree and the chart can be printed and shared with family members and an individual’s doctor.
|
|
Nanotechnology Characterization Laboratory
|
Research Initiative
|
FDA
|
NCI, NIEHS
|
The Nanotechnology Characterization Laboratory (NCL) performs and standardizes the preclinical characterization of nanomaterials intended for cancer therapeutics and diagnostics developed by researchers from academia, government, and industry. The NCL serves as a national resource and knowledge base for cancer researchers and facilitates the development and translation of nanoscale particles and devices for clinical applications.
|
|
NAS/NOWS Working Group for Behavioral Health Coordinating Council (BHCC) Opioids and Controlled Substances Subcommittee
|
Committee, Work group, Advisory group, or Task Force
|
CDC, CMS, HRSA, IHS, SAMHSA
|
NICHD, NIDA
|
This working group meets regularly to coordinate information and develop joint efforts to reduce the effects of neonatal opioid withdrawal syndrome/neonatal abstinence syndrome (NOWS/NAS).
|
|
NASEM Study on Medication-Assisted Treatment for Opioid Use Disorder
|
Health Survey
|
SAMHSA
|
NIDA
|
The National Institute on Drug Abuse (NIDA) has partnered with the Substance Abuse and Mental Health Services Administration (SAMHSA) to commission a workshop and report from the National Academy of Sciences to support the dissemination of accurate patient-focused information about treatments for addiction, and to help proved scientific solutions to the current opioid crisis. As part of that process, an ad hoc committee under the auspices of the National Academies of Sciences, Engineering, and Medicine will conduct a study of the evidence base on medication-assisted treatment (MAT) for opioid use disorder (OUD). Specifically, the committee will:
•Review current knowledge and gaps in understanding regarding the effectiveness of MAT for treating OUD,
•Examine available evidence on the range of parameters and circumstances in which MAT can be effectively delivered (e.g., duration of treatment, populations, settings, and interventions to address social determinants of health (SDH) as a component of MAT),
•Identify challenges in implementation and uptake,
•Identify additional research needed on MAT for OUD.
Based on its review of the literature and input from the public workshop, the committee will develop a report with its findings and conclusions.
|
|
National Action Alliance for Suicide Prevention (NAASP)
|
Committee, Work group, Advisory group, or Task Force
|
ACL, CDC, HRSA, IHS, OS, OSG, SAMHSA
|
NIMH, NIAAA, NIDA, OD/DPCPSI/OBSSR, OD/DPCPSI/ODP
|
Founded in September 2010, the NAASP is a public-private partnership designed to advance the National Strategy for Suicide Prevention in the United States. The NAASP''s Research Prioritization Task Force (RPTF) was charged with developing a process to prioritize suicide prevention research efforts and consider ways to integrate science and service to ensure that suicide deaths decrease significantly within the next decade. The RPTF released the Nation''s first suicide research agenda, A Prioritized Research Agenda for Suicide Prevention: An Action Plan to Save Lives. The research agenda includes an overarching goal to advance suicide prevention research more rapidly, seeking ways to reduce suicide deaths and attempts by 20 percent in five years and by 40 percent or greater in ten years. In 2015, the RPTF produced the "U.S. National Suicide Prevention Research Efforts: 2008-2013 Portfolio Analyses." The analyses revealed that investments in suicide research are severely lagging, but there is a growing knowledge base of intervention research. In 2016, the NIH Office of Disease Prevention supported the Pathways to Prevention Workshop, Advancing Research to Prevent Youth Suicide in 2016, which further refined methodological challenges and data linkage needs relevant to multiple NIH Institutes and HHS agencies. The National Institute of Mental Health (NIMH) developed a request for information relevant to this workshop, and a federal partners meeting in the spring of 2017 considered additional actions in response to the workshop recommendations. Two multi-IC RFAs were issued in response to this effort (MH RFA 18-400; MH RFA 18-410). In 2016, NAASP adapted the goal of reducing US suicide rates by 20 percent in 10 years. NIMH supports this goal by identifying practice-ready suicide prevention research. For example, in May 2017, the NIMH led the meeting, the “State of Suicide Prevention in Emergency Care” with participation from the NIH Office of Emergency Care Research (NIGMS), SAMHSA, and the CDC. Surveillance, policy and practices challenges, as well as research gaps were identified for further strategic efforts.
|