- U.S. Department of Health & Human Services
- National Institutes of Health
- Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI)
- Accumulating Data to Optimally Predict Obesity Treatment (ADOPT) Core Measures Working Group Meeting
- Acquisition Management Committee (AMC)
- Adjuvant Working Group
- Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA)
- Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Executive Steering Committee
- Advisory Committee for the Office of NIH History and Stetten Museum
- Aging-associated Autoimmunity in the Baltimore Longitudinal Study of Aging (BLSA)
- American Indian Alaska Native Hawaii Native Program Interest Group
- American Indian/Alaska Native (AI/AN) Task Force of the National Action Alliance for Suicide Prevention (NAASP)
- Antibody Interest Group (ABIG)
- Asthma Disparities Working Group: A Subcommittee of the President’s Task Force on Environmental Health Risks and Safety Risks to Children
- Autism Centers of Excellence (ACE) Evaluation Implementation and Oversight Committee
- Autoimmune Diseases Coordinating Committee (ADCC)
- Behavioral Health Coordinating Committee Subgroup on Trauma
- Benefits for National Research Service Award (NRSA) Postdoctoral Researchers
- Best Pharmaceuticals for Children Act (BPCA) Oncology Working Group
- Biohazard Concerns Consulting Committee (BCCC)
- Biomedical Research Informatics Computing System (BRICS) for eyeGENE
- Botanical Workshop Planning Group
- BRAIN Initiative
- Bridging Interventional Development Gaps (BrIDGs) Committee
- CARB National Database of Resistant Pathogens Implementation Working Group
- Cell Cycle Interest Group
- Center for Inherited Disease Research Board of Governors
- Centers for AIDS Research (CFAR) Steering Committee
- Certificate of Confidentiality Coordinators Working Group
- Children in Adversity Inter-Agency Working Group
- Children's HHS Interagency Leadership on Disasters (CHILD) Working Group
- ClinGen Steering Committee
- Clinical and Translational Science Awards (CTSA) Strategic Goal IV Committee
- Clinical Pharmacogenetics Implementation Consortium (CPIC)
- Clinical Text De-Identification
- Clinical Trials Stewardship Working Group
- Collaborative Research on Addiction at NIH (CRAN)
- Common Data Elements (CDEs) Task Force
- Correlative Studies in the National Cancer Institute's (NCI) Precision Medicine Trials
- Cytisine Workgroup
- Cytokine Interest Group
- Department of Health and Human Services Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children
- Diabetes Mellitus Interagency Coordinating Committee (DMICC)
- Diversity and Outreach Committee
- Division of Library Services (DLS) Advisory Committee (DLSAC)
- Down Syndrome Consortium
- East Asia (e-ASIA) Joint Research Forum
- Emergency Care Research Project
- Extended Project Period Pilot
- Extramural-Intramural Collaborations Workgroup of Committee Overseeing the Program
- Eyegene Common Data Elements and Vocabulary Standards
- Federal Tuberculosis (TB) Task Force
- Federal Working Group on Bone Diseases
- Federal Working Group on Dietary Supplements (FWGoDS)
- Final Research Performance Progress Report (RPPR)
- Genomes to Natural Products Network (GNPN)
- Genomic Data Sharing Policy Implementation Working Group
- Genomic Nursing Science Blueprint: Next Steps
- Genotype-Tissue Expression (GTEx) Working Group
- Geroscience Interest Group (GSIG)
- Glycobiology Scientific Interest Group (SIG) Steering Committee (Intramural)
- Healthy People 2020 – Sleep Health Working Group
- High Containment Task Force
- HIV/AIDS Vaccine Scholars Program (K01)
- Human BioMolecular Atlas Platform (HuBMAP)
- Human Subjects Research Advisory Committee (HSRAC)
- Human Tissues and Organs Resource for Research (HTORR) Steering Committee
- Human, Heredity and Health in Africa (H3Africa)
- Hydrocephalus and Related Disorders Working Group
- IC Animal Events Response Committee
- Imaging Informatics Tools for Biomedical Research
- Imaging Tools for Cancer Research
- Immunology Interest Group (IIG)
- Inclusion Operating Procedures Workgroup (IOPW )
- Indo-U.S. Joint Steering Committee on Collaboration on Diabetes Research
- Inflammatory Disease Interest Group
- Influenza Interest Group
- Initiative on the Rigor and Reproducibility of Research Findings
- Innovative Research to Improve Maintenance of Weight Loss Working Group
- Integrated Database for Managing Animal Study Proposals and Animal Inventory
- Inter-Society Coordinating Committee (ISCC) for Practitioner Education in Genomics
- Interagency Autism Coordinating Committee
- Interagency Breast Cancer and Environmental Research Coordinating Committee (IBCERCC)
- Interagency Collaborative to Advance Research in Epilepsy (ICARE)
- Interagency Modeling and Analysis Group (IMAG)
- Interagency Pain Research Coordinating Committee (IPRCC)
- Interagency Workgroup on Child Abuse and Neglect (FEDIAWG)
- Interagency Working Group on Medical Imaging (IWGMI) within the National Science and Technology Council's Committee on Science
- Interagency Working Group on Scientific Collections
- International Epidemiology Databases to Evaluate AIDS (IeDEA) Executive Committee
- Intramural Program Planning Subcommittee of the NIH Program Planning and Implementation Working Group on Indo-US Collaboration on Prevention of Sexually Transmitted Diseases and HIV/AIDS
- Intramural Research Program Bioresource
- Johns Hopkins Global Center on Childhood Obesity Steering Committee
- Joint Addiction, Aging, and Mental Health Data Access Committee
- Kidney, Urologic, and Hematologic Diseases Interagency Coordinating Committee (KUHICC)
- Knowledge Management Tool-kit to Facilitate Research Portfolio Analysis
- Learning Collaborative for Implementation Science in Global Brain Disorders
- Mali Research Support and Service Center
- Martin Delaney Collaboratory Program Management Team
- Mental Health Across the Lifespan Initiative
- Mind-Body Modalities Scientific Interest Group (SIG)
- Mitochondrial Disorders Working Group
- Mucosal Immunology and Microbiome Interest Group (MIMIG )
- Multi-Agency Tissue Engineering Science Working Group
- Multi-Purpose Prevention Technologies Funders Group
- Muscular Dystrophy Coordinating Committee (MDCC)
- Nanomedicine-Nanotech Interest Group
- National Advisory Board on Medical Rehabilitation Research
- National Biomedical Imaging Archive (NBIA)
- National Cancer Informatics Program (NCIP) Nanotechnology Working Group
- National Cancer Institute (NCI) Alliance of Glycobiologists
- National Family Health History Group
- National Nanotechnology Initiative (NNI) Nanotechnology Signature Initiative on Nanotechnology for Sensors and Sensors for Nanotechnology: Improving and Protecting Health, Safety, and the Environment
- National Nanotechnology Initiative (NNI) Nanotechnology Signature Initiative on Nanotechnology Knowledge Infrastructure: Enabling National Leadership in Sustainable Design
- National Nanotechnology Initiative (NNI) Nanotechnology Signature Initiative on Nanotechnology Knowledge Infrastructure: Enabling National Leadership in Sustainable Design (NKI)
- NCI - NIH Enterprise Vocabulary Services (EVS) Research Terminology Content, Standards, and Systems Collaboration
- NCI-NHLBI Cardiotoxicity Working Group
- NCI-NHLBI Cohort Collaboration Working Group Meeting
- Neural Prostheses Working Group
- Neurobiobank Implementation Team
- Neuroprosthetics Committee
- NIDA Genetics Coordinating Committee
- NIDA-NIAAA Neuroscience Working Group
- NIEHS-NIDDK Joint Postdoctoral Fellowship
- NIH Adverse Drug Reaction Working Group
- NIH Autism Coordinating Committee (ACC)
- NIH Big Data to Knowledge (BD2K)
- NIH Biomedical Information Science and Technology Initiative Consortium (BISTI)
- NIH Blueprint for Neuroscience Research
- NIH Caribbean American Planning Committee
- NIH Citizen Science Interest Group
- NIH Common Fund Illuminating the Druggable Genome program
- NIH Common Fund Protein Capture Reagents Program
- NIH Common Fund's Single Cell Analysis Working Group
- NIH Disaster Research Response (DR2) Program
- NIH Flow Cytometry Interest Group
- NIH Glycoscience Working Group
- NIH Health Literacy Workgroup
- NIH Hispanic Health Research Scientific Interest Group (SIG)
- NIH Human Subjects Protection Liaison Committee
- NIH Institute and Center International Representatives Forum
- NIH Institute and Center Liaison Language Access Plan (LAP) Committee
- NIH Interagency Coordination mHealth Workgroup
- NIH Language Access Steering Committee
- NIH Medical Rehabilitation Coordinating Committee
- NIH MicroRNA (miRNA) Interest Group
- NIH Nanoscale Science, Engineering and Technology (NSET) Subcommittee Activities
- NIH Nutrition Research Task Force
- NIH Obesity Research Task Force
- NIH Pain Consortium
- NIH Planning and Evaluation (P&E) Officers Committee
- NIH Proteomics Interest Group (ProtIG)
- NIH Robotics Working Group
- NIH SBIR/STTR Reauthorization Implementation Group
- NIH Scientific Interest Group
- NIH Scientific Program and Review Interest Group (SPRIG)
- NIH Single IRB Evaluation and Metrics Sub-Committee
- NIH Single IRB Policy Implementation Committee
- NIH Single IRB Policy Implementation Exceptions Sub-Committee
- NIH Single IRB Policy Implementation Guidance and Training Sub-Committee
- NIH Social Media Collaboration Group
- NIH Steering Committee on Trans-Institute Angiogenesis Research Program (TARP)
- NIH Strategic Communications Planning Project
- NIH Tuberculosis (TB) Working Group
- NIH Working Group on Down Syndrome
- NIH Working Group on Emergency Medicine
- NIH Working Group on Women in Biomedical Careers
- NIH-BMGF Child Health and Development Working Group
- NIH-Networking Information Technology Research and Development Program (NITRD) Consortium
- NIH-Pfizer Centers for Therapeutic Innovation (CTI) Steering Committee
- NIH-South Africa Medical Research Council (MRC) Program
- NIH-TÜBITAK Collaborative Biomedical Research Program
- NIH/FDA Leadership Council’s Workgroup on Preclinical Toxicology
- NIH/Gates Malaria Working Group
- NIH/Gates Zika Working Group
- No Deadlines Working Group
- NTP Literature-Based Evaluations of Shift Work at Night, Light at Night and Circadian Disruption
- Nutrition Research Coordinating Committee (NRCC)
- OppNet Steering Committee
- Outcome Study of the NIH Loan Repayment Programs Working Group
- Outcomes Effectiveness Research Interest Group (OER-IG)
- Outreach Network
- Pacific Basin Consortium for Environment and Health
- Pancreatic Ductal Adenocarcinoma (PDAC) Progress Working Group
- Pandemic Prediction and Forecasting Science and Technology Working Group (PPFST)
- Participant Protection and Data Management Steering Committee
- Pediatric Adverse Event Terminology Harmonization Working Group
- Physician-Scientist Workforce Implementation Group
- Planning Group for Challenges in GxE Research in the Behavioral and Social Sciences
- Post-traumatic Stress Disorder (PTSD)/Traumatic Brain Injury (TBI), Suicide Prevention National Research Action Plan (NRAP) Workgroup
- Precision Medcicine Initative (PMI "All of Us") and Families Working Group
- PregSource Management Team
- Prevention Research Coordinating Committee (PRCC)
- Public Private Partnerships
- Reducing Burden in Peer Review Working Group
- Report on Carcinogens (RoC) Evaluation of Five Selected Viruses: Epstein-Barr virus (EBV), human immunodeficiency virus type 1 (HIV-1), human T-cell lymphotropic virus type 1 (HTLV-1), Kaposi sarcoma-associated herpesvirus (KSHV), Merkel-cell polyoma
- Research Prioritization Task Force of National Action Alliance for Suicide Prevention (NAASP)
- SBIR Peer Review Improvement Working Group
- Science of Behavior Change Working Group
- SCOPE (Spinal Cord Outcomes Partnership Endeavor)
- Sleep and Obesity Working Group
- Special Populations Research Forum
- SRO Technical Competencies Subcommittee (STCS)
- Structured Data Capture (SDC) Forms Working Group
- Systems Biology Scientific Interest Group (SysBioSIG)
- TGF-beta Superfamily Interest Group
- The ABCD Collaborators Group
- The Blueprint Neurotherapeutics Network (BPN)
- The Breast Cancer & the Environment Research Program (BCERP)
- The Initiative for Multipurpose Prevention Technologies (IMPT) Supporting Agency Collaboration Committee (SACC)
- The Pain Special Interest Group (Pain SIG) Seminar Series
- Therapeutics Discovery Project (TDP) Team
- Tobacco and Nicotine Research Interest Group (TANRIG)
- Trans NIH Program Leadership Committee (PLC)
- Trans NIH Working Group on Point of Care Technologies (POCT-WG)
- Trans-Agency Early-Life Exposures and Cancer (TAEEC) Working Group
- Trans-NIH Advisory Group (TAG), Therapeutics for Rare & Neglected Diseases (TRND) Program
- Trans-NIH Alzheimer's Disease Work Group
- Trans-NIH American Indian and Alaska Native Health Communications and Information Work Group
- Trans-NIH Behavioral and Social Sciences Research (BSSR) Coordinating Committee (BSSR CC)
- Trans-NIH Bioethics Committee
- Trans-NIH BioMedical Informatics Coordinating Committee (BMIC)
- Trans-NIH Chronic Inflammation Interest Group (CIIG)/Organizing Committee for a Trans-NIH Workshop
- Trans-NIH Community Engagement Interest Group
- Trans-NIH Coordinating Committee on HIV and Aging
- Trans-NIH Coordinating Committee on Research on Women's Health (CCRWH)
- Trans-NIH Diabetes Complications Working Group
- Trans-NIH Environmental Influences on Child Health Outcomes (ECHO) Working Group
- Trans-NIH Etiology of Health Disparities Working Group
- Trans-NIH Fragile X Research Group
- Trans-NIH Genetics/Genomics Coordinating Committee for HIV/AIDS Research
- Trans-NIH Genomic Data Submission and Management Taskforce
- Trans-NIH Global Health Research Working Group (GHRWG)
- Trans-NIH Liver Cancer Working Group
- Trans-NIH Microbiome Working Group (TMWG)
- Trans-NIH Minority Health and Health Disparities Reporting Working Group
- Trans-NIH Mitochondrial Disorders Working Group (MiDi)
- Trans-NIH Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) Working Group
- Trans-NIH Neurofibromatosis Working Group
- Trans-NIH Plan for HIV-Related Research Coordinating Committees
- Trans-NIH Proteostasis Scientific Interest Group (SIG)
- Trans-NIH Rare Diseases Working Group
- Trans-NIH Rehabilitation Research Coordinating Committee
- Trans-NIH Sarcoidosis Working Group
- Trans-NIH Scientific Interest Group: Breastfeeding and Human Lactation Research
- Trans-NIH Scientific Research Interest Working Group on Biomarkers in Pediatric Therapeutics
- Trans-NIH Sex as a Biological Variable Working Group
- Trans-NIH Sleep Research Coordinating Committee
- Trans-NIH Small Vessel Biology and Disease Working Group
- Trans-NIH Structural Birth Defects Working Group
- Trans-NIH Structural Birth Defects Working Group (SBDWG)
- Trans-NIH Training Advisory Committee (TAC )
- Trans-NIH Transgenerational Working Group
- Trans-NIH Tuberous Sclerosis Complex (TSC) Working Group
- Trans-NIH Web Material Transfer Agreement Project
- Trans-NIH Women’s Health Research Group
- Trans-NIH Working Group on Climate Change and Health
- Trans-NIH Working Group on Clinical Applications of Genomics
- Trans-NIH Working Group on Coding Minority Health and Health Disparities
- Trans-NIH Working Group on Defining Minority Health and Health Disparities
- Trans-NIH Working Group on Household Air Pollution
- Trans-NIH Working Group on Intervention Science
- Trans-NIH Working Group on Intimate Partner Violence and HIV
- Trans-NIH Xenopus Working Group
- Trans-NIH Zebrafish Coordinating Committee
- Translational Research Interest Group
- Treating for Two Interagency Working Group (Medications in Pregnancy)
- U. S. Government Interagency Working Group on Nanotechnology Environmental, and Health Implications (NEHI), of the Nanoscale Science, Engineering, and Technology Subcommittee (NSET) of the National Science and Technology Council (NSTC)
- U.S. Department of Agriculture (USDA)-NIH-Industry Nutrition Behavior Working Group
- U.S.-Brazil Working Group on Biomedical Collaborative Research
- U.S.-China Program for Biomedical Collaborative Research Working Group
- U.S.-China Program for Collaborative Research Toward a Cure for HIV
- U.S.-India Joint Working Group on Prevention of Sexually Transmitted Diseases (STDs) and HIV/AIDS
- U.S.-Russia Collaboration on Research Related to HIV/AIDS
- US Domestic Cohort Program: Multicenter AIDS Cohort Study, Women's Interagency HIV Study
- Vaccines for Cancer Prevention Working Group
- Vertebrate Animal Section Working Group
- Videos as Application Materials Working Group
- Virology Interest Group
- Women-Owned, and Socially and Economically Disadvantaged Businesses Working Group
- Working Group on Hydrocephalus and Hindbrain Malformations
- Working Group on the NIH Project to Establish Biomedical Beamlines at NSLS-II
Accumulating Data to Optimally Predict Obesity Treatment (ADOPT) Core Measures Working Group Meeting
This group is developing core measures for obesity research studies.
Acquisition Management Committee (AMC)
The AMC serves as the NIH forum to advise and make recommendations on acquisition policies, establish NIH acquisition procedures, address common acquisition issues by sharing ideas and information, and resolve acquisition problems.
Adjuvant Working Group
Program staff from the National Institute of Allergy and Infectious Diseases (NIAID), National Cancer Institute (NCI), Biomedical Advanced Research and Development Authority (BARDA), United States Agency for International Development (USAID), and regulatory staff from the Food and Drug Administration (FDA) exchange information about ongoing programs related to novel adjuvants for infectious disease vaccines, identify high priority research areas (and gap areas), and discuss ideas to accelerate progress in adjuvant research through better access to information and resources.
Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA)
The Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA) aims to enhance the effective use of evidence and help overcome implementation challenges related to prevention, screening and treatment of HIV among adolescents (ages 15 to 24) in sub-Saharan Africa by catalyzing collaboration and communication among implementation scientists, program implementers and policymakers. The Center for Global Health Studies at Fogarty is launching the initiative in collaboration with the Office of the Global AIDS Coordinator and other NIH Institutes and Centers.
Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Executive Steering Committee
ATN Network governance and coordination is provided by an Executive Committee, comprised of the Principal Investigator (PI) and Project Director of the ATN Coordinating Center, the Vice Chair(s) for the subgroups of the Adolescent Medicine Leadership Group, the PI and Project Director of the Data and Operations Center, the Chair and Vice Chair of the Adolescent Medicine Trials Units PI, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Project Scientist. Other NIH Institute and Center scientists, Chairs and Vice Chairs of ancillary clinical and community coordinator groups, and staff of the Community Advisory Board serve as non-voting ad hoc members. The Executive Committee ensures adherence to the established policies and procedures of the ATN.
Advisory Committee for the Office of NIH History and Stetten Museum
The NIH established this committee to inform the Office of NIH History and Stetten Museum (ONHM) on efficient and proactive approaches to collecting and preserving NIH history. This committee facilitates the partnership of the ONHM with the NIH National Library of Medicine (NLM), the NIH Office of Management Division of Management Support (Records Management), the U.S. National Archives and Records Administration, and local universities. The committee also helps establish roles among these partners, so NIH documents and objects of historic significance are known by all partners and quickly placed in the appropriate environment for possible display, safe-keeping, or scholarly research.
Aging-associated Autoimmunity in the Baltimore Longitudinal Study of Aging (BLSA)
The National Institute of Environmental Health Sciences (NIEHS) and the National Institute on Aging (NIA) jointly funded a post-doctoral fellow in epidemiology based at NIEHS and a post-bac laboratory fellow at NIA to facilitate collaborative research on the role of environmental factors, inflammation and immune senescence in aging-associated autoimmunity. Autoimmune diseases impact 5 to 8% of the U.S. population and rates are increasing for unknown reasons. Growing evidence supports a role for immune modulating environmental exposures in human and experimental studies across many autoimmune diseases, but the factors influencing the onset of autoimmunity and its natural history remain unexplained. Elevated antinuclear antibodies (ANA) are a marker of self-reactivity seen across multiple autoimmune diseases, and may precede the development of autoimmune disease by years. At the same time, ANA are seen in 12-15% of healthy individuals in the U.S. population, with a higher prevalence in women (similar to many autoimmune diseases), and increase with age in both women and men. This collaboration builds on data collected in the long-term BLSA. We hypothesize that higher ANA prevalence will be associated with older age and immune aging as reflected by shorter telomeres, will be associated with lower levels of vitamin D, and may also be associated with higher levels of inflammation and more rapid telomere length attrition. Specific aims include: 1) describing the prevalence, persistence, and incidence of ANA, and examining whether there is a significant increase in ANA associated with aging as well as evaluating associations of ANA with clinical covariates and environmental factors associated with inflammation (e.g. smoking, obesity, stress, biomarkers of inflammation, and infections); 2) describing ANA prevalence and incidence in relation to measured vitamin D levels and exploring whether vitamin D deficiency is associated with increased rates of ANA; and 3) describing ANA prevalence and incidence in relation to telomere length and telomere length trajectory and determining whether telomere length may modify or mediate AHA associations with age. This work also takes advantage of data available in the NIEHS Sister STUDY and the NHANES and will foster future collaborative research on the impact of environment on healthy aging.
American Indian Alaska Native Hawaii Native Program Interest Group
The purpose of this interest group is to promote discussion, share ideas, and coordinate activities within and outside the NIH, relating to the specific needs of the research community working with American Indian/Alaska Native/Hawaiian Native peoples on their health concerns and needs.
American Indian/Alaska Native (AI/AN) Task Force of the National Action Alliance for Suicide Prevention (NAASP)
The NAASP was established in September 2010 at the request of Department of Health and Human Services Secretary and the Department of Defense Secretary. It is a public-private partnership designed to advance the National Strategy for Suicide Prevention in the United States. The NAASP's AI/AN Task Force - co-chaired by the Director of the Indian Health Service (IHS), the Deputy Bureau Director of the Bureau of Indian Affairs (BIA), and the executive director of the National Indian Youth Leadership Project - is charged with identifying priorities for suicide prevention efforts in AI/AN communities, including advancing research priorities to address suicide prevention among AI/AN communities. IHS and BIA have served as the overall federal leads for the task force, with the National Institute of Mental Health (NIMH), National Institute on Drug Abuse (NIDA), and the Office of Behavioral and Social Sciences Research (OBSSR).
Antibody Interest Group (ABIG)
The NIH ABIG promotes information exchange and interaction among NIH scientists who work on various aspects of antibody engineering and therapy. The success of antibody therapy requires a thorough understanding of biological systems in relation to molecular and cell biology, immunology, biochemistry, and microbiology, as well as diseases such as cancer, autoimmunity, and infectious diseases. Interest in antibody therapy crosses traditional biomedical disciplinary boundaries. ABIG provides an open forum for multidisciplinary discussion among colleagues who otherwise may have limited interaction. The principal ABIG activities are monthly meetings on current topics as well as an annual symposium on the NIH campus. The monthly ABIG meetings are open to everyone interested. These meetings are devoted to research seminars on numerous aspects of antibody engineering and therapy presented by both NIH scientists and outside speakers.
Asthma Disparities Working Group: A Subcommittee of the President’s Task Force on Environmental Health Risks and Safety Risks to Children
This Working Group, composed of NIH Institutes and Centers as well as other federal agencies, developed a "Coordinated Federal Action Plan to Reduce Racial and Ethnic Asthma Disparities in Children," which presents specific strategies to coordinate and collaborate across federal agencies and build on existing federal programs and partnerships that can address factors that impact asthma disparities. The Working Group meets quarterly and is co-chaired by the National Heart, Lung, and Blood Institute (NHLBI), the Environmental Protection Agency (EPA), the Department of Housing and Urban Development, and the Centers for Disease Control and Prevention (CDC).
Autism Centers of Excellence (ACE) Evaluation Implementation and Oversight Committee
The NIH ACE Evaluation Implementation and Oversight (AEIO) Committee was formed in 2008 to design, guide, and oversee the evaluation of the NIH Autism Centers of Excellence (ACE) program. The ACE program is supported by five NIH Institutes and Centers, which have a representative serving on the AEIO, all as equal partners. The AEIO is chaired by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and meets periodically to consult on the design and implementation of the ACE program evaluation.
Autoimmune Diseases Coordinating Committee (ADCC)
The ADCC provides a forum for the coordination of research efforts in autoimmunity and autoimmune diseases among various stakeholders including the NIH Institutes, other federal agencies such as the Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC), and private organizations with an interest in autoimmune diseases. The ADCC meets twice yearly to discuss a broad range of basic, preclinical, and clinical endeavors.
NIH Participants: NIAID, CSR, FIC, NCATS , NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NINDS, NINR
HHS OPDIVs Participants: FDA, CDC, HRSA
Behavioral Health Coordinating Committee Subgroup on Trauma
The Behavioral Health Coordinating Committee Subgroup on Trauma aims to share information and identify and facilitate collaborative, action-oriented approaches to address the Department of Health and Human Services behavioral health agenda pertaining to trauma without duplication of effort across the Department.
Benefits for National Research Service Award (NRSA) Postdoctoral Researchers
A survey found that postdoctoral NRSA benefits were not equivalent to benefits for postdoctoral researchers funded through other agencies or research project grants. This group provided recommendations to address the issue and, in 2017, will contribute to an implementation plan.
Best Pharmaceuticals for Children Act (BPCA) Oncology Working Group
Testing medications in children presents considerable scientific, clinical, ethical, technical, and logistical challenges. The BPCA established a program at NIH for pediatric medication development. BPCA activities include identifying and prioritizing medications needing study; developing study requests; and conducting studies on priority medications after manufacturers decline to do so. The BPCA Priority List includes key therapeutic needs in the treatment of children and adolescents, organized by Therapeutic Area, which can be a group of conditions, a population subgroup, or a setting of care. Each year, a few Therapeutic Areas are selected for discussion. Working groups meet to identify the gaps in knowledge and set priorities. One of these working groups is organized around oncology. The ongoing focus of this group includes determining how the drug development process can be improved for oncology drugs used in children including proposal and discussion of possible drugs to be studied.
Biohazard Concerns Consulting Committee (BCCC)
The Biohazard Concerns Consulting Committee (BCCC) is responsible for assisting NIH program officers/program directors with resolving biohazard concerns that could not be resolved at the Institute and Center level. The BCCC functions as an NIH consulting body to advise program staff on the most appropriate resolution, what further information is required in order to resolve the concern, or on any other matter related to the biohazard concern. The BCCC is composed of persons from many different NIH Institutes and Centers with expertise that span across laboratory biosafety and biological, chemical, and radiation hazards.
Biomedical Research Informatics Computing System (BRICS) for eyeGENE
BRICS is a collaborative and extensible web-based system developed by the NIH Center for Information Technology (CIT) to support the collection of research studies and clinical trials, using a set of modular components that cover all stages of the research life cycle. eyeGENE® has been collaborating with the CIT staff to instantiate the BRICS system to make eyeGENE® data available to vision researchers.
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a Presidential goal aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a new, dynamic picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact in both time and space. Long desired by researchers seeking new ways to treat, cure, and even prevent brain disorders, this picture will address major gaps in our current knowledge and provide unprecedented opportunities for exploring exactly how the brain enables the human body to record, process, utilize, store, and retrieve vast quantities of information, all at the speed of thought.
Bridging Interventional Development Gaps (BrIDGs) Committee
The BrIDGs Program receives proposals to collaborate on preclinical therapeutic development projects from a variety of external entities. Unlike other disease/organ system-centric Institutes and Centers, the BrIDGs Program within the National Center for Advancing Translational Sciences (NCATS) may receive proposals across the spectrum of disease areas. The Committee is comprised of representatives from across a number of other Institutes and Centers to allow BrIDGs Program Staff to receive disease/biology area-specific insight into the candidate proposals under consideration.
CARB National Database of Resistant Pathogens Implementation Working Group
As specified in the Combating Antibiotic-Resistant Bacteria (CARB) National Action Plan, the National Institute of Allergy and Infectious Diseases (NIAID), the National Library of Medicine (NLM), and the National Human Genome Research Institute (NHGRI) are working with other U.S. government partners (the Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC)) to pilot the National Database of Resistant Pathogens, which will be populated with about 300 strains, including both genomic and associated clinical data. Additional sequencing and analysis of high-priority reference strains will be conducted, and it is anticipated that more than 150 strains will be sequenced at very high quality to populate the database.
Cell Cycle Interest Group
The Cell Cycle Interest Group is composed of researchers at NIH and in the local area who are interested in cell cycle and DNA replication in prokaryotes and eukaryotes. The group hosts talks by experts in the field throughout the year. Regular meetings include annual symposia with keynote addresses by leaders from the cell cycle field, followed by presentations by individuals in the group describing recent results in their labs. Special meetings are arranged for guest researchers who present an hour long seminar.
Center for Inherited Disease Research Board of Governors
This board is responsible for oversight of the Center for Inherited Disease Research. The Center for Inherited Disease Research is a cooperative program that carries out large-scale genotyping and DNA sequencing. The Center is supported under a contract administered by the National Human Genome Research Institute (NHGRI) on behalf of 11 Institutes and Centers.
Centers for AIDS Research (CFAR) Steering Committee
Program officers and directors from the nine co-funding Institutes, one participating Center, and one office in the NIH Office of the Director form this committee that meets monthly to discuss the scientific management of the CFAR program. The goal of the committee is to ensure that the CFARs fulfill their mission of facilitating HIV research through synergistic collaborations, mentoring of young and new investigators, and multidisciplinary projects involving basic, clinical, behavioral, and translational research.
Certificate of Confidentiality Coordinators Working Group
This trans-NIH working group is convened to discuss policies related to Certificates of Confidentiality, which are issued to help researchers protect the privacy of human research participants enrolled in biomedical, behavioral, clinical, and other forms of sensitive health-related research. Certificates protect against compulsory legal demands, such as court orders and subpoenas, for identifying information or identifying characteristics of a research participant.
Children in Adversity Inter-Agency Working Group
The Children in Adversity Interagency Working Group is the main mechanism for implementing interagency coordination under P.L. 109-95. There are five U.S. Government departments represented in this working group: U.S. Department of State, U.S. Department of Labor, U.S. Department of Agriculture, U.S. Department of Defense and U.S. Department of Health and Human Services; and two U.S. Government agencies: U.S. Agency for International Development and Peace Corps. One of the main functions of this interagency working group is to review and strengthen implementation and progress of the U.S. Government Action Plan on Children in Adversity.
Children's HHS Interagency Leadership on Disasters (CHILD) Working Group
The U.S. Department of Health and Human Services (HHS) established the Children's HHS Interagency Leadership on Disasters (CHILD) Working Group in 2010 to identify and comprehensively integrate the activities related to the needs of children across all HHS inter- and intra-governmental disaster planning activities and operations. Co-led by the Administration for Children and Families and the Assistant Secretary for Preparedness and Response, the group then developed recommendations for how HHS can improve the delivery of care to children who are impacted by disasters.
ClinGen Steering Committee
The Clinical Genome Resource (ClinGen) is an NIH-funded consortium focused on building standard frameworks, tools, and a central resource that defines the clinical relevance of genes and variants for use in medicine and research. The Steering Committee is the governing body of the consortium that sets the vision for the program, identifies the clinical domains that are the focus of curation efforts, engages with external stakeholders including the FDA and professional societies, and evaluates progress. The Steering Committee comprises Principal Ivestigators from each of the cooperative agreements and representation from the National Human Genome Research Institute (NHGRI), the National Institute of Child Health and Human Development (NICHD), the National Cancer Institute (NCI), and the National Library of Medicine's National Center for Biotechnology Information (NLM NCBI). ClinGen was funded in Sept 2013.
Clinical and Translational Science Awards (CTSA) Strategic Goal IV Committee
The goal of the committee is to identify and develop effective partnerships between academic researchers and community stakeholders that allow for participation, discovery, application, and dissemination of science that improves public health, reduces health disparities, and promotes the translation of the results of clinical and translational research into practice and public policy. The community engagement workgroup sponsors several activities, supported by its several interest groups.
Clinical Pharmacogenetics Implementation Consortium (CPIC)
The goal of the CPIC is to address some of the barriers to implementation of pharmacogenetic tests into clinical practice. The CPIC was formed as a shared project between PharmGKB (Pharmacogenomics Knowledgebase) and the Pharmacogenomics Research Network.
Clinical Text De-Identification
Computational de-identification seeks to develop tools that will automatically remove all of the personal identifiers, patient names and names connected to the patient, dates, identifiers such as hospital numbers and accession numbers from clinical narrative text. It also aims to understand the statistics and issues surrounding such removal with the goal of generating de-identified documents that can be used in clinical research while protecting patient privacy. Researchersj at the National Library of Medicine (NLM) have developed the NLM-Scrubber, a publicly available application for de-identifying clinical documents. They are collaborating with the National Cancer Institute (NCI) and the Clinical Center (CC) Biomedical Translational Research Information System, who are using the NLM-Scrubber software, as well as two NIH grantees.
Clinical Trials Stewardship Working Group
To address clinical trial stewardship, this group aims to improve the assessment of the merits, feasibility, oversight, transparency, and dissemination of summary results for clinical trials.
Collaborative Research on Addiction at NIH (CRAN)
Following a year-long study of addiction-related research-portfolios in the National Institute on Drug Abuse (NIDA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Cancer Institute (NCI), NIH leadership in 2012 called for functional integration of research to enhance and expand activities related to substance use, abuse, and addiction. As a result, the NIAAA, NIDA, and NCI established Collaborative Research on Addiction at NIH (CRAN) as a framework to enable these Institutes and Centers to coordinate and share resources and expertise in order to create synergies, address new research opportunities, and meet public-health needs. In 2014, several Funding Opportunity Announcements (FOAs) were released to supplement ongoing research and research training grants that broadened their aims or expertise to address multiple substances or other CRAN-related goals. Other FOAs were released to support research on social media as a tool to better understand the patterns of substance use and information exchange related to multiple substances; or to develop prevention/treatment interventions using social media tools. Eleven grants were funded through these opportunities. Additionally, CRAN has taken the lead on developing a major new initiative entitled, "The Adolescent Brain Cognitive Development Study," a large longitudinal study to prospectively examine the effects of substance use on the human brain during early adolescence into young adulthood.
Common Data Elements (CDEs) Task Force
The CDE Task Force is charged by the NIH Scientific Data Council to [advise it concerning how to?] improve the communication and coordination of NIH efforts to identify, develop, and promote the use of CDEs in NIH-supported research. Previously, as a working group under the aegis of the Trans-NIH BioMedical Informatics Coordinating Committee (BMIC), the group provided advice to the development of a CDE Repository that serves as a platform for searching, harmonizing, developing, and disseminating CDEs used by NIH Institutes and Centers; Task Force members continue to work with the National Library of Medicine (NLM) to improve this publicly available platform. The Task Force also maintains a web portal with information about NIH-supported CDE initiatives that are intended for use by NIH-funded researchers. The Task Force continues to take steps to encourage the use of CDEs by NIH-funded researchers, minimize overlap and redundancy in CDE initiatives, improve interoperability and compatibility between and among CDE initiatives and with other standards development activities (e.g., related to electronic health records), and assist NIH Institute and Center staff and researchers in identifying and using CDEs that are relevant to their projects.
NIH Participants: NLM, CC, CIT, NCATS , NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, OD, DPCPSI, OBSSR, ORWH, OER, OSP
HHS OPDIVs Participants: AHRQ
Other Participants: USUHS
Correlative Studies in the National Cancer Institute's (NCI) Precision Medicine Trials
The National Human Genome Research Institute (NHGRI) and the NCI are collaborating to design correlative sub-studies for the return of genomic research results in NCI-funded precision medicine clinical trials such as Molecular Analysis for Therapy Choice (MATCH), which harness genomic sequencing technologies to assign research participants to study arms and therapies based on their molecular tumor profile.
The Cytisine Workgroup provides oversight and support of pre-clinical studies that will provide data of suitable quality and integrity to support applications to the U.S. Food and Drug Administration (FDA) and other regulatory agencies. This group works on and oversees studies with an objective to determine the safety profile and establish a maximum tolerated dose and no observed adverse effect level of cytosine in various definitive toxicology and safety pharmacology studies to support an Investigational New Drug application for use of this natural product as a smoking cessation aide. The studies will be performed in accordance with the U.S. FDA's "Good Laboratory Practice for Nonclinical Laboratory Studies" as described in 21 CFR Part 58. Information from this study may be used to determine the suitability of the proposed human dose.
Cytokine Interest Group
The NIH Cytokine Interest Group provides a forum for the interaction of scientists with a common interest in the immunology, molecular biology and physiology of cytokines. Major activities include a series of mini-symposia by Washington, D.C. area scientists dealing with multidisciplinary aspects of cytokine research, as well as seminars by outside speakers several times a year.
Department of Health and Human Services Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children
The National Institute of Child Health and Human Development (NICHD) is the lead for this committee that has the purpose of updating the U.S. Pediatric HIV treatment guidelines and serves as executive secretary. The Department's Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children (the Panel), a working group of the Office of AIDS Research Advisory Council, reviews new data on an ongoing basis and provides regular updates to the guidelines. The guidelines are available on the AIDSinfo website. These updated guidelines address the use of combination antiretroviral therapy for HIV-infected infants, children, and adolescents. Guidance on management of adverse events associated with use of antiretroviral drugs in children and a detailed review of information about safety, efficacy, and pharmacokinetics of antiretroviral agents in children is also included.
Diabetes Mellitus Interagency Coordinating Committee (DMICC)
The DMICC, authorized by Public Law 93-354, fosters collaborations between federal agencies that conduct or support diabetes-related activities and provides a forum for members to share information and ideas to synergize federal efforts to combat diabetes. DMICC meetings, held several times a year, help members identify emerging issues and opportunities and develop ways in which different government components can work together and build upon each agency's expertise and resources. In addition to NIH Institutes and Centers, DMICC member organizations include non-NIH member representatives from the Agency for Healthcare Research and Quality (AHRQ), the Centers for Disease Control and Prevention (CDC), the Centers for Medicare and Medicaid Services (CMS), Health Resources and Services Administration (HRSA), the Food and Drug Administration (FDA), the Department of Health and Human Services Office of Minority Health (HHS-OMH), the Indian Health Service (IHS), the Veterans Health Administration (VHA), the U.S. Department of Agriculture (USDA), and the Department of Defense (DoD).
NIH Participants: NIDDK, CSR, NCATS , NCCIH, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM
HHS OPDIVs Participants: FDA, AHRQ, CDC, HRSA
Other Participants: CMS, VHA, USDA, DoD, IHS, HHS-OMH, HHS-OASH
Diversity and Outreach Committee
The goal of the committee is to identify and recruit promising young scientists from underrepresented populations. The committee is also involved in outreach activities to local schools in order to recruit high school students for internships in the intramural research programs of the National Institute on Drug Abuse (NIDA) and National Institute on Alcohol Abuse and Alcoholism (NIAAA). The committee also reviews applications from principal investigators and their mentees who are seeking to work as post-baccalaureate students or post-doctoral fellows within these intramural programs.
Division of Library Services (DLS) Advisory Committee (DLSAC)
The DLSAC provides advice and guidance on matters pertaining to budget, program, and policy and is solely advisory in nature, providing non-binding but informed guidance.
Down Syndrome Consortium
The NIH has joined with organizations interested in Down syndrome to form a consortium that fosters the exchange of information on biomedical and biobehavioral research on the chromosomal condition. The consortium allows NIH to inform the Down syndrome community of advances in the field, ongoing studies, and potential avenues for future research. In turn, those who work in Down syndrome research and patient care can share their experiences and ideas for potential research. A single, comprehensive forum makes the research effort to address Down syndrome more effective, minimizing duplication of effort and capitalizing on the knowledge of those with the greatest experience in the field. Individuals with Down syndrome and family members are represented on the consortium, which also includes the NIH Down Syndrome Working Group that coordinates NIH-supported Down syndrome research, and representatives from prominent Down syndrome and pediatric organizations.
East Asia (e-ASIA) Joint Research Forum
The e-ASIA Joint Research Program facilitates and supports international joint research projects with countries in East Asia and the Pacific regions on a multilateral basis. The National Institute of Allergy and Infectious Diseases (NIAID) joined the program in 2013; the member countries include Cambodia, Indonesia, Japan, Laos, Malaysia, Myanmar (Burma), New Zealand, the Philippines, Thailand, the United States, and Vietnam.
Emergency Care Research Project
Fogarty's Center for Global Health Studies is leading a project to address barriers and solutions to conducting research in emergency or acute care settings in low-and middle-income countries. The goal of the project is to promote research that improves immediate and long-term outcomes for patients and populations with acute, potentially life or limb threatening conditions by focusing on the care provided in the first minutes to hours of illness or injury. Through identifying unique challenges, exploring lessons learned and articulating new strategies, methods and tools, we hope to facilitate more research and inform research designs specific to these settings.
Extended Project Period Pilot
This group is developing and executing an NIH pilot project to test the concept and viability of extending grant project periods for up to 7 years. The pilot is based on the justification and risk management plan provided to the Department of Health and Human Services in support of this concept.
Extramural-Intramural Collaborations Workgroup of Committee Overseeing the Program
The Extramural-Intramural Collaborations Workgroup is a subcommittee of the NIH Clinical Center-Extramural Collaborations Committee that oversees the Extramural-Intramural Program. The goal of this workgroup is to develop recommendations for making the NIH Clinical Center (CC) available to extramural investigators in order to implement a recent recommendation of the Scientific Management Review Board to make the Clinical Center a true national resource. The specific plan developed by this group in its monthly meetings was presented to the NIH Advisory Board for Clinical Research.
Eyegene Common Data Elements and Vocabulary Standards
The goal of this collaboration is to review, enhance, and incorporate Eyegene 6,000 common data elements into the Logical Observation Identifier Names and Codes (LOINC®). LOINC® is supported by the National Library of Medicine (NLM) and is a federally required standard system for reporting clinical variables and survey instruments.
Federal Tuberculosis (TB) Task Force
The Federal Tuberculosis (TB) Task force is a collaboration of federal agencies involved in tuberculosis research and control efforts in the United States. It was established in 1991 by the Director of the Centers for Disease Control and Prevention (CDC) to address multidrug-resistant TB outbreaks between 1985-1992. Today, it still serves to facilitate coordination of TB activities and research amongst federal agencies.
Federal Working Group on Bone Diseases
The Federal Working Group on Bone Diseases consists of representatives from federal agencies and voluntary organizations concerned with bone health. It offers a forum for sharing information and for facilitating the development of collaborative bone research activities based on the mission of each agency.
Federal Working Group on Dietary Supplements (FWGoDS)
The FWGoDS includes representatives from NIH and other federal agencies that share information and discuss issues, initiatives, and research related to dietary supplements. The FWGoDS serves as means of communication between NIH and its federal partners in order to co-fund research; expand opportunities for research-investigator training; and strengthen collaborative efforts involving dietary supplement research, education, and communication across the government.
NIH Participants: ODP, CC, CSR, FIC, NCATS , NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, OBSSR
HHS OPDIVs Participants: FDA, AHRQ, CDC, HRSA
Other Participants: ODPHP, AOA, US Consumer Product Safety Commission, Federal Trade Commission, NASA, US Army Research Institute of Environmental Medicine, USDA, Uniformed Services University of Health Sciences
Final Research Performance Progress Report (RPPR)
This group developed the Final Research Performance Progress Report (F-RPPR) to replace the Final Progress Report for closeout. The F-RPPR was made effective for final progress reports submitted after January 1, 2017.
Genomes to Natural Products Network (GNPN)
The ultimate goal of the Genomes to Natural Products Network (GNPN) is to develop genomics and synthetic biology based platforms to overcome current barriers and accelerate natural products discovery. The GNPN is a network led by staff from the National Institute of General Medical Sciences (NIGMS) and three cross-disciplinary teams. It provides a platform for activities among our members to leverage knowledge and resources, and maximize the dissemination and accessibility of the resources it develops to the scientific community.
Genomic Data Sharing Policy Implementation Working Group
At the request of the Office of Science Policy, the Office of Extramural Research (OER) assumed leadership of the Genomic Data Sharing Policy Implementation Working Group in the summer of 2014. This working group was responsible for implementing the NIH Genomic Data Sharing policy, which was issued in August 2014. The group included representatives from across the Institutes and Centers, the NIH Office of the Director, as well as the NIH Intramural Program. The group reported to the Genomic Data Sharing Senior Oversight Committee. The OER issued a companion notice with information for applicants and grantees at the same time, and provided staff-wide training in September 2014 and carried targeted training into 2015. The Working Group completed its work in the fall of 2015 but remains available as needed.
Genomic Nursing Science Blueprint: Next Steps
The goal of this initiative is to consider opportunities to facilitate genomic nursing research, to identify researcher resources and gaps, to explore exemplar models to be used as a framework that supports research, and to envision a platform for promotion of genomic nursing research and collaboration.
Genotype-Tissue Expression (GTEx) Working Group
The Common Fund's Genotype-Tissue Expression (GTEx) program aims to study human gene expression and regulation in multiple tissues, providing valuable insights into the mechanisms of gene regulation and, in the future, its disease-related perturbations. Genetic variation between individuals will be examined for correlation with differences in gene expression level to identify regions of the genome that influence whether and how much a gene is expressed.
Geroscience Interest Group (GSIG)
During fiscal year 2012, NIH formed the GSIG to enhance opportunities for considering intersections between research on the basic biology of aging and the health conditions of interest across many NIH institutes and centers that do not focus on the aging process as such, with a long-range view towards translation. The GSIG holds monthly meetings of an Executive Committee and, with the support of the various participating NIH Institutes and Centers, sponsors an ongoing series of seminars on current research in geroscience, presented by leading investigators (typically 4 times a year); the latter are broadcast publicly and archived on the NIH videocasting system. The New York Academy of Sciences, together with the NIH Geroscience Interest Group, the Gerontological Society of America and the American Federation for Aging Research organized the Disease Drivers of Aging: 2016 Advances in Geroscience Summit on April 13–14, 2016, in New York City. This landmark event convened basic, translational, and clinical researchers from academic institutions, pharmaceutical companies, government agencies, and non-profit organizations, who work in the disparate fields of HIV/AIDS, oncology, diabetes, and aging research in an effort to better understand the complex relationship between chronic diseases and age-associated decline.
Glycobiology Scientific Interest Group (SIG) Steering Committee (Intramural)
This Steering Committee is comprised of NIH intramural scientists, NIH extramural program officers, and researchers from the Food and Drug Administration (FDA), the National Institute of Standards and Technology (NIST), and the Department of Energy (DOE). The committee organizes a seminar series; an annual NIH/FDA Glycosciences Research Day Meeting (averaging over 300 attendees); a Mentoring and Networking Luncheon for graduate students and postdoctoral fellows to meet with staff from federal agencies and learn about NIH extramural programs and intramural job opportunities; and Special Topics in the Glycosciences Courses. In addition, the Glyco Scientific Interest Group (SIG) maintains an email listserv to distribute information on meetings, jobs, funding opportunities and seminars. The SIG cross posts with other NIH SIGs that share similar interests. The SIG makes an annual speaker nomination for the Wednesday Afternoon Lecture Series, and if chosen, hosts the speaker. The 2016 Glycosciences Research Day Meeting was attended by staff from NIH institutes and from other federal agencies including: the FDA, NIST, Naval Medical Research, and U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).
Healthy People 2020 – Sleep Health Working Group
This interagency working group provides oversight for the "Sleep Health" topic and objectives under Healthy People 2020. The Healthy People initiative is organized by the Department of Health and Human Services and provides a science-based framework for national objectives promoting health and preventing disease. The working group discusses topic content, evaluates progress toward achieving existing sleep health objectives, and identifies and prioritizes potential new sleep health objective opportunities.
HIV/AIDS Vaccine Scholars Program (K01)
The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide salary and research support to investigators who are within ten years of completing their degree or residency training. Research and mentorship must be in the field of HIV/AIDS vaccine development, using nonhuman primates as pre-clinical models. These awards will provide 3 years of support for intensive research career development under the guidance of an experienced mentorship team, with expertise in both development of nonhuman primate vaccine models and in translation of the results of investigations performed in this model to work in humans. The expectation is through this sustained period of research career development and training, awardees will launch independent research careers and become competitive for new research project grant (e.g., R01) funding.
Human BioMolecular Atlas Platform (HuBMAP)
This trans-NIH working group was assembled to develop the HuBMAP concept to become a potential new NIH Common Fund program. The HuBMAP concept aims to develop an international platform that will pull data from many sources and integrate them into an evolving cellular map of tissues and organs across the human body all the way to single cell level. The HuBMAP working group organized a symposium with external stakeholders on June 15, 2016, released a Request for Information, and prepared and presented the HuBMAP concept to advisory and decision bodies, including NIH Council of Councils and the NIH Institute and Center directors meetings. The concept evolved through Phase 1 of strategic planning was approved on Dec 22, 2016 to progress to Phase 2 for a potential launch in 2018.
Human Subjects Research Advisory Committee (HSRAC)
The primary responsibility of the HSRAC is to advise the NIH Deputy Director for Intramural Research on policies and procedures regarding the conduct of human subjects research in the NIH Intramural Research Programs. The HSRAC is comprised of the Deputy Director for Intramural Research, who is the chair, the Director of the Office for Human Subjects Research Protections, the 14 NIH Institutional Review Board Chairs, the Director of the Clinical Center (CC), and the Chief of the Clinical Center Department of Bioethics.
Human Tissues and Organs Resource for Research (HTORR) Steering Committee
The NIH supports a program to provide a broad range of normal and diseased human biospecimens to NIH researchers (intramural and extramural). The program is operated by the not-for-profit organization, the National Disease Research Interchange, which interacts with investigators to understand their needs and procures tissues for research projects via a network of tissue acquisition centers. At the NIH level, the HTORR is managed by a steering committee composed of representatives from a number of Institutes and Centers. The steering committee meets one or more times per year to review the number and types of tissues provided, the projects served, and operating procedures.
Human, Heredity and Health in Africa (H3Africa)
The Human Heredity and Health in Africa (H3Africa) Initiative aims to facilitate a contemporary research approach to the study of genomics and environmental determinants of common diseases with the goal of improving the health of African populations. To accomplish this, the H3Africa Initiative aims to contribute to the development of the necessary expertise among African scientists, and to establish networks of African investigators.
Hydrocephalus and Related Disorders Working Group
The group shares information about ongoing research activities and identifies research needs and opportunities for collaboration, both across NIH institutes and with non-governmental organizations that support hydrocephalus research.
Imaging Informatics Tools for Biomedical Research
Advanced image content analysis R&D that is used for understanding and classifying visual content in medical images can also help expedite diagnosis and treatment of disease. In partnership with the National Cancer Institute (NCI), National Institute of Allergic and Infectious Disease (NIAID), and other organizations, ongoing research in this area relates to cervical cancer, HIV, tuberculosis (TB, with special focus on pediatric, multi-drug resistant (MDR) and extensively drug resistant (XDR) TB), and malaria.
Computer-aided TB Screening of Chest X-rays: This is a collaboration with AMPATH (Academic Model Providing Access to Healthcare), an organization supported by USAID to treat more than 180,000 HIV patients in Kenya. The project leverages LHNCBC's in-house expertise in image processing, machine learning, systems development and communication to acquire and analyze digital chest radiographs at remote rural sites and automatically screen HIV-positive patients for evidence of pulmonary TB and other important pathology. HIV and TB are comorbidities and early immediate detection of the disease impacts their treatment and can help in reducing their spread. The automated system, which has been trained on a large collection TB positive and normal chest X-rays, provides an immediate response to the medical officer in the field based on detection of radiographic manifestations on the digital chest X-ray image that are consistent with pulmonary TB. Some of the image data sets used in this research have been made available to the research community and have been downloaded by over 220 researchers worldwide. This project received an award from HHS Ignite, a departmental initiative of the HHS IDEA Lab, in 2014.
MalariaScreener: This project also relies on LHNCBC's expertise in image analysis and machine learning that are applied to the development of algorithms that can automatically measure the quantitative content of parasites in blood films of malaria-infected patients. Inspecting blood films under the microscope, which is the standard method for malaria diagnosis, is a laborious and error-prone process that depends on the skill of a microscopist. An automated system for reading the hundreds of millions blood films examined for malaria every year will reduce the diagnostic burden, which is a crucial factor in the fight against malaria. The algorithms implementing this automation power MalariaScreener, software that runs on a smartphone and reports back the parasite load in a blood film image captured by the phone's camera when attached to a conventional microscope. Researchers at LHNCBC are training the software with more than 200,000 manually annotated cell images acquired at Chittagong Medical College Hospital, Chittagong, Bangladesh, so that it learns to discriminate automatically between infected and uninfected red blood cells. Collaborators on the project include Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand, and University of Missouri. The project has won an award from the HHS Ventures Fund, a departmental initiative of the HHS IDEA Lab, in 2015.
Imaging Tools for Cancer Research
The National Library of Medicine (NLM) continued its collaboration with the National Cancer Institute's (NCI) Center for Cancer Research, Laboratory for Cell Biology, on 3D Imaging Informatics for High Resolution Electron Microscopy. The group developed software tools and visualization using nano-scale modalities (Transmission Electron Tomography and Ion Ablation - Scanning Electron Microscopy); refined image analysis software based on Insight Toolkit for HIV virion detection; developed software for NCI's new microscope data; developed graphics processing unit-based image reconstruction software for 3D protein spikes from the surface of HIV virions; managed segmentation tasks for murine myocyte stem-cell differentiation; and collected data from Boundary Marking Tool for the Cervical Biopsy Study at 5 sites in the United States (University of Oklahoma), Nigeria, Costa Rica, Netherlands and Spain. NCI and the American Society for Colposcopy and Cervical Pathology used NLM's Teaching Tool to help train medical students and practitioners to detect cervical cancer.
Immunology Interest Group (IIG)
The NIH Immunology Interest Group (IIG) organizes activities designed to promote information exchange and interactions among NIH scientists interested in the field of immunology, broadly defined. Interactions are facilitated via weekly meetings on current topics as well as an Annual Immunology Workshop.
Inclusion Operating Procedures Workgroup (IOPW )
The IOPW is a trans-NIH working group that reports to the Extramural Activities Working Group Subcommittee on Inclusion Governance. The IOPW is comprised of staff from the Institutes and Centers and the Office of the Director who have technical and/or policy experience with NIH inclusion policies and procedures.
Indo-U.S. Joint Steering Committee on Collaboration on Diabetes Research
In June 2012, the U.S. and Indian governments signed a "Joint Statement on Collaboration on Diabetes Research" to foster collaborative efforts between the United States and India that could lead to advances in science and technology important to understanding, preventing, and treating diabetes and its complications. These efforts take advantage of complementary scientific strengths and other resources in both countries. The NIH and the Indian Council of Medical Research (ICMR), along with the Department of Biotechnology (DBT), India, are the primary agencies responsible for implementing the joint statement. The NIH efforts are led by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The heads of NIDDK and ICMR co-chair a Joint Steering Committee that oversees implementation of the joint statement. Members of the Joint Steering Committee are drawn from NIDDK, the Fogarty International Center (FIC), the ICMR, and DBT.
Inflammatory Disease Interest Group
The purpose of this special interest group is to encourage better communication, thoughtful discussions, and NIH-wide collaboration so that new treatment modalities might be developed for the many chronic inflammatory and fibrotic diseases that affect human health. The group will convene daylong symposia, two or three times a year, on various inflammatory-disease topics and will host a bimonthly seminar series focused on basic and translational aspects of inflammation. The group is open to all persons within NIH and associated agencies (e.g., the Food and Drug Administration (FDA) and the U.S. Department of Agriculture (USDA)) that share an interest in basic and translational inflammation research.
Influenza Interest Group
The Influenza Interest Group organizes activities designed to promote information exchange and interactions among NIH area scientists interested in influenza virus. Interactions are facilitated by monthly meetings covering research topics being worked on by NIH and regional labs. The group discusses topics with a unique mix of perspectives from basic, translational, and regulatory scientists, and provides an ideal opportunity to learn and network.
Initiative on the Rigor and Reproducibility of Research Findings
NIH has undertaken a broad initiative to improve the transparency and rigor of biomedical research. This includes: * Development of training materials and workshops on experimental design and rigor that will be made available broadly to the biomedical research community in multiple modalities * Pilot studies on the use of checklists to enhance systematic review of grant applications (multiple NIH Institutes and Centers) * Pilot studies on formally including a review of the "premise" of preclinical trials (multiple NIH Institutes and Centers) * Pilot programs to support replication studies of preclinical research (multiple NIH Institutes and Centers) * Development of policies requiring applicants to address inclusion of both sexes in preclinical research, informed by a public Request for Information (led by the Office of Research on Women's Health and the Office of Extramural Research (OER)) * Development and dissemination of consensus standards for cell culture use and tools to characterize cell lines and reagents (led by the National Institute of General Medical Sciences and the National Human Genome Research Institute) * Launch of PubMed Commons, a pilot system enabling peer post-publication review of publications indexed by PubMed (the National Library of Medicine) * Research awards that provide a longer period of support to investigators * Changes to the NIH biographical sketch to allow for investigators to provide fuller context for their previous work (led by OER) * Engagement with stakeholders about rigor and reproducibility, including discussions with journal editors in June 2014 (in partnership with the Nature Publishing Group and Science journals) leading to the development of consensus principles for reporting research findings that over 130 journals have endorsed, and a public Request for Information on reagent-related barriers to reproducible research (led by the NIH Office of the Director)
Innovative Research to Improve Maintenance of Weight Loss Working Group
The goal of this Working Group was to identify challenges that make maintaining long-term weight loss so difficult, including physiologic, psychosocial, and behavioral factors.
Integrated Database for Managing Animal Study Proposals and Animal Inventory
A committee that provides software development, and systems support for database systems used in animal facilities for animal medical records, housing per diems, rodent breeding records, and management of animal study proposals.
Inter-Society Coordinating Committee (ISCC) for Practitioner Education in Genomics
The ISCC facilitates sharing interactions among professional societies, agencies, and health systems. It intends to enhance the accrual of knowledge and skill among practitioners applying genomic results to clinical care. In its start-up phase, the ISCC focused primarily on physicians and dentists. It has since expanded to engage and collaborate with allied practitioner groups such as nurse practitioners, physician assistants, pharmacists, and nurses comprising integrated health care teams. It will continue to add other relevant professions, such as genetic counselors, as well as add to the reviewed and searchable educational resources on its website.
The Interagency Autism Coordinating Committee (IACC) is a Federal advisory committee that coordinates all efforts within the Department of Health and Human Services (HHS) regarding autism spectrum disorder (ASD). Through its inclusion of Federal and public members, the IACC helps to ensure that an extensive range of perspectives and ideas are represented and discussed in a public forum. The IACC mission includes efforts to:
* Provide advice to the Secretary of Health and Human Services regarding Federal activities related to autism spectrum disorder.
* Facilitate the exchange of information on and coordination of ASD activities among the member agencies and organizations.
* Increase public understanding of the member agencies' activities, programs, policies, and research by providing a public forum for discussions related to ASD research and services.
Interagency Breast Cancer and Environmental Research Coordinating Committee (IBCERCC)
The IBCERCC is a congressionally mandated body comprised of 18 voting members, including representatives of other federal agencies; non-federal scientists, physicians, and other health professionals from clinical, basic, and public health sciences; and advocates for individuals with breast cancer. The primary mission is to facilitate the efficient and effective exchange of information on breast cancer research activities among the member agencies, and to advise NIH and other federal agencies in the solicitation of proposals for collaborative, multidisciplinary research, including proposals to further evaluate environmental and genomic factors that may be related to the etiology of breast cancer. The Committee serves as a forum and assists in increasing public understanding of the member agencies' activities, programs, policies, and research, and in bringing important matters of interest forward for discussion. The IBCERCC is composed of three subcommittees, all with efforts targeted at identifying gaps, reducing redundancy and enhancing collaboration among Federal agencies. The State-of-the-Science Subcommittee aims to develop a comprehensive strategy and advise NIH in the solicitation of applications for collaborative, transdisciplinary research, and outline key research questions and methodologies. The Research Process Subcommittee aims to: set research priorities, based on the work of the State-of-the-Science Subcommittee; reduce redundancies across Federal and non-governmental organizations; develop a process for soliciting research and fostering collaborations; highlight issues of peer review; and identify appropriate models for agencies to work together. The Research Translation, Dissemination, and Policy Implications Subcommittee aims to: identify successful models and gaps in research translation and dissemination and recommends improvements; recommend policies to address translation and dissemination and precautionary public health policies supported by scientific evidence; identify methods to expand public participation in research translation and dissemination processes; and identify methods to more actively engage patient advocates and other stakeholders.
Interagency Collaborative to Advance Research in Epilepsy (ICARE)
ICARE is an interagency epilepsy working group that includes broad representation across the NIH Institutes and Centers involved in epilepsy-related research, as well as the Department of Defense (DoD), the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA), and Veterans Affairs (VA) and multiple epilepsy research and patient advocacy groups with a primary focus on biomedical research. Annual meetings provide a forum for sharing information about ongoing and planned epilepsy research activities, highlighting advances, discussing needs and opportunities, and promoting increased collaboration toward common research goals.
Interagency Modeling and Analysis Group (IMAG)
The IMAG is comprised of program directors from nine government agencies in the United States, including the NIH, the National Science Foundation (NSF), Department of Energy (DOE), Department of Defense (DoD), Department of Agriculture (USDA), National Aeronautics and Space Administration (NASA), Department of Veterans Affairs (VA), Food and Drug Administration (FDA), and the Intelligence Advanced Research Projects Activity (IARPA). The purpose of IMAG is to bring together program officers who have a shared interest in supporting modeling and analysis methods in biomedical, biological, and behavioral systems. IMAG has promoted and supported a wide variety of modeling, notably the multi-scale modeling initiative, which was originally a multi-agency funding opportunity announcement and continued on by various IMAG agencies through other funding opportunity announcements. The most recent multi-agency funding opportunity was issued in 2015 and expires in 2018. IMAG is planning a tenth anniversary consortium meeting to be held in March 2017.
Interagency Pain Research Coordinating Committee (IPRCC)
The Interagency Pain Research Coordination Committee is an Affordable Care Act mandated committee to coordinate pain research activities across the government.
Interagency Workgroup on Child Abuse and Neglect (FEDIAWG)
The overall goals of the FEDIAWG are to provide a forum through which staff from relevant Federal agencies can communicate and exchange ideas concerning child maltreatment related programs and activities and provide a basis for collective action through which funding and resources can be maximized. There are three Subcommittees and related workgroups, specifically the Domestic Violence Subcommittee, Prevention Subcommittee, Research Subcommittee, and the NIH Child Abuse and Neglect Working Group.
Interagency Working Group on Medical Imaging (IWGMI) within the National Science and Technology Council's Committee on Science
The IWGMI is the result of a Congressional call for a Federal Medical Imaging Research Initiative. This working group serves as a permanent home within the White House as part of the National Science and Technology Council's Committee on Science to better coordinate, understand, and accelerate imaging science and technologies across federal agencies. The IWGMI is chartered to develop a roadmap for medical imaging research and development, advance medical imaging technologies to combat disease, and support the development of a high-skilled workforce in this field.
Interagency Working Group on Scientific Collections
The purpose of the Interagency Working Group on Scientific Collections (IWGSC) is to address the scientific, environmental, societal, and national security needs for Federal scientific collections by providing a forum for coordination and collaboration among Federal departments and agencies on policies and practices for managing scientific collections, in particular, policies and practices being developed and implemented in response to the March 20, 2014 memorandum from the Director of the Office of Science and Technology Policy (OSTP) to the heads of executive departments and agencies on Improving the Management of and Access to Scientific Collections. In addition, the IWGSC will coordinate the implementation of recommendations for scientific collections that were included in the October 6, 2010 memorandum from the Director of OSTP to the heads of executive departments and agencies on Policy on Scientific Collections and fulfill the requirements of Section 104 of the America COMPETES Reauthorization Act of 2010 [Public Law 111-358] on Federal Scientific Collections.
International Epidemiology Databases to Evaluate AIDS (IeDEA) Executive Committee
The IeDEA executive committee oversees the management of IeDEA. The Executive Committee meets monthly by teleconference and at least annually face to face. Other U.S. Government participants in global HIV care, such as the President's Emergency Plan for AIDS Relief (PEPFAR) representatives, the Centers for Disease Control and Prevention (CDC), and the U.S. Agency for International Development (USAID), participate in the annual meetings. IeDEA is designed to evaluate outcomes of HIV infection and treatment using data aggregated from multiple clinical sources. Extremely large databases are able to explore scientific questions by the individual members of the consortium. IeDEA studies rare outcomes, such as cancer, and complex patient populations, such as pediatric populations. IeDEA also serves as a platform for implementation science evaluations, cost effectiveness research, and surveillance of population level effects.
Intramural Program Planning Subcommittee of the NIH Program Planning and Implementation Working Group on Indo-US Collaboration on Prevention of Sexually Transmitted Diseases and HIV/AIDS
The purpose of this subcommittee is to draft the periodic Requests for Proposals for the I-to-I program (Intramural-to-India) that solicits and supports small scale research collaborations between NIH intramural and Indian scientists.
Intramural Research Program Bioresource
Scientists in collaborating NIH institutes are working together to establish a resource that will be useful across the NIH intramural research community for precision medicine efforts.
Johns Hopkins Global Center on Childhood Obesity Steering Committee
The National Institute of Child Health and Human Development (NICHD) provides the NIH project scientist for the Global Obesity Prevention Center (GOPC) and services on the Johns Hopkins Global Center on Childhood Obesity Steering Committee. The GOPC is comprised of 3 ongoing, large-scale projects, and 4 key units. Each unit supports important projects and plays a crucial role in our fight against the obesity epidemic by building the field of obesity prevention globally.
Joint Addiction, Aging, and Mental Health Data Access Committee
NIH Data Access Committees (DACs) review and approve or disapprove requests from extramural and intramural researchers for proposed secondary research uses of controlled-access datasets overseen by the DAC. DACs are formed based on topic expertise and are not necessarily specific to an Institute or Center. This document is intended to provide a framework for general principles for DAC operations. The document has been reviewed and approved by the Participant Protection and Data Management (PPDM) Steering Committee and the Senior Oversight Committee (SOC) for trans-NIH Genome-wide Association Studies (GWAS) policy implementation. The PPDM will make modifications or updates to this document as needed, and the SOC will review the changes when appropriate.
Kidney, Urologic, and Hematologic Diseases Interagency Coordinating Committee (KUHICC)
The Kidney, Urologic, and Hematologic Diseases Interagency Coordinating Committee (KUHICC) encourages cooperation, communication, and collaboration among all Federal agencies involved in kidney, urology, and hematology research and other activities. Public Law 99-158 created the KUHICC in 1987 and emphasized the importance of interagency coordinating meetings. Meetings focus on interagency collaboration to elicit ideas from meeting participants to enhance current research directions within the National Institutes of Health and to form partnerships among agencies.
Knowledge Management Tool-kit to Facilitate Research Portfolio Analysis
This project is a collaboration to develop tools to assist with portfolio analysis. The overarching goal is to create opportunities for users to interact with sophisticated information retrieval tools, supported by visualization software to steer the machine learning process as well as to refine the classification output. Success will conserve users' time and maximize the efficient integration of users' judgment and expertise. The focus is on the evaluation and optimization of currently available tools and resources.
Learning Collaborative for Implementation Science in Global Brain Disorders
This group is working toward integrating implementation science methodologies, frameworks and approaches in brain and nervous systems science research in low- and middle-income countries. The Fogarty International Center (FIC) gathered grantees of the trans-NIH Global Brain Disorders Program, program implementers, policy-makers, and other stakeholders in neuroscience and nervous system health in conjunction with the Society for Neuroscientists of Africa Annual Meeting to facilitate and deepen connections between brain disorders researchers and stakeholder research users; encourage evidence-based interventions related to brain disorders; encourage resolution of bottlenecks and challenges in the implementation of interventions related to brain disorders; and lastly, promote locally driven priorities related to research on brain disorders informed by the research, program implementer, and policy-making communities. The group is executing additional training and networking opportunities in 2016.
Mali Research Support and Service Center
The Service Center provides administrative and financial support to all NIH intramural and extramural funding in Mali in order to ensure good and transparent management of NIH resources according to U.S. government standards. The National Institute of Allergy and Infectious Diseases (NIAID) Office of Global Research oversees the day-to-day implementation of this contract and coordinates interactions between the contractor and various NIH programs working in Mali.
Martin Delaney Collaboratory Program Management Team
This team of NIH program officials and medical officers was formed to help manage the Martin Delaney Collaboratory program, which is focused on basic and translational research toward finding a cure for HIV infection. The team communicates with members of the program through quarterly conference calls and annual face-to-face meetings. The goal of the team is to identify obstacles impeding progress in the field and to help develop solutions to overcome these obstacles.
Mental Health Across the Lifespan Initiative
In July 2015, the National Institute of Mental Health (NIMH) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) launched a two-year collaboration with Delta Sigma Theta Sorority, Inc., called the Mental Health Across the Lifespan initiative. This initiative seeks to raise awareness about issues affecting women and their families throughout the lifespan, including mental disorders such as postpartum depression, and issues that can impact mental health, including bullying and aging. The initiative harnesses the power of Delta Sigma Theta's membership network to extend the reach of NIH's research-based information directly into the communities served by more than 1,000 chapters in the United States and abroad. The collaboration expands and intensifies NIH's efforts to increase awareness about the diagnosis, treatment, and latest research in the area of postpartum depression. Expansion of efforts to increase support, education, and research related to postpartum depression was a key provision of the Affordable Care Act of 2010 (PL 111-148).
Mind-Body Modalities Scientific Interest Group (SIG)
This SIG brings together scientists and clinicians to facilitate constructive dialogue and scientific and experiential inquiry about mind-body practices; discuss appropriate research and analytic methods to understand the mechanisms and efficacy of mind-body practices through monthly seminars and talks.
Mitochondrial Disorders Working Group
The Mitochondrial Disorders Working Group encourages and facilitates basic mechanistic research on the mitochondria with the goal of nucleating trans-NIH communication about mitochondrial biology. It also seeks to facilitate clinical research into primary mitochondrial disorders and into disorders and health in which mitochondrial function and dysfunction play an important role. This group additionally works to leverage resources and improve therapies. Subgroups form on an ad hoc basis in order to develop specific initiatives.
Mucosal Immunology and Microbiome Interest Group (MIMIG )
The goal of the MIMIG is to provide a forum for scientific discussion and sharing of reagents and models in the field of mucosal immunology. The scope is broad and includes immunology of the nasopharyngeal, gastrointestinal, respiratory, genitourinary, oral, and ocular mucosal tissues, as well as basic, clinical, and translational research topics. The MIMIG organizes a symposium each year and hosts lab presentations or journal article reviews on the NIH campus on a monthly basis.
Multi-Agency Tissue Engineering Science Working Group
The goal of this interagency working group is to facilitate communication in the tissue engineering/regenerative medicine field across departments/agencies by regular information exchanges, co-sponsorship of scientific meetings and workshops, monitor technology by undertaking cooperative assessments of the status of the field, provide support for tissue engineering research through interagency funding opportunity announcements, foster technology transfer and translation of research advances into practical applications, and promote the formulation and use of standards for research tools and product development.
Muscular Dystrophy Coordinating Committee (MDCC)
This committee coordinates activities relevant to the various forms of muscular dystrophy across NIH and other federal agencies. The committee also includes members from patient organizations. Strategic planning efforts by the coordinating committee led to the development of an Action Plan for the Muscular Dystrophies, which contains specific research objectives appropriate to the missions of all committee member agencies and organizations, and thus serves as a central focus for research coordination. The plan is available at the MDCC web site.
Nanomedicine-Nanotech Interest Group
The Nano Scientific Interest Group is an NIH inter-institute Interest Group that brings together diverse, multidisciplinary researchers with common research interests in nanotechnology, nanoscience, and nanomedicine.
National Advisory Board on Medical Rehabilitation Research
The Director of NIH mandated establishment of the National Advisory Board on Medical Rehabilitation Research. The Board advises the directors of NIH, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and NICHD's National Center for Medical Rehabilitation Research on matters and policies relating to the Center's programs. The Board is comprised of 12 members representing health and scientific disciplines related to medical rehabilitation and six members representing persons with disabilities.
National Biomedical Imaging Archive (NBIA)
The NBIA is a searchable repository of in vivo images that provides the biomedical research community, industry, and academia with access to image archives to be used in the development and validation of analytical software tools that support: 1) Lesion detection and classification; 2) accelerated diagnostic imaging decision; and, 3) quantitative imaging assessment of drug response. NBIA provides access to imaging resources that will improve the use of imaging in biomedical research and improve clinical decision support by increasing the efficiency and reproducibility of imaging cancer detection and diagnosis, leveraging imaging to provide an objective assessment of therapeutic response, and ultimately enabling the development of imaging resources.
National Cancer Informatics Program (NCIP) Nanotechnology Working Group
The NCIP Nanotechnology Working Group was established for researchers with a specific interest in informatics and computational approaches to nanotechnology, with a particular emphasis on nanomedicine. The goal of this working group is to demonstrate the scientific potential of federating nanotechnology databases through pilot projects aimed at integrated semantic search and retrieval of nanomedicine and nanotoxicology datasets that are applicable across nanoscience. Meetings are held weekly via WebEx and are open to anyone interested in participating in and contributing to the working group's discussions and activities. The group is comprised of over 20 participants from academia, government (including several NIH Institutes, the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA), the Environmental Protection Agency EPA), the National Institute of Standards and Technology (NIST)), and industry.
National Cancer Institute (NCI) Alliance of Glycobiologists
The Alliance is a part of the NCI's Early Detection Research Network. The Alliance, a consortium of eight Tumor Glycomics Laboratories and research partners, is working to reveal the cancer-related dynamics of complex carbohydrates and to develop new, validated, clinical biomarkers for early cancer detection.
National Family Health History Group
Federal, state, and other stakeholders focus on increasing awareness of the value of family health history in managing health risks. National Family History Day is designated by the Surgeon General for increasing awareness of the above. Members of this group coordinate public communications and resource development. Recent efforts include updating and disseminating communication materials for National Family History Day and expanding membership to include family history tool developers.
National Nanotechnology Initiative (NNI) Nanotechnology Signature Initiative on Nanotechnology for Sensors and Sensors for Nanotechnology: Improving and Protecting Health, Safety, and the Environment
This is an interagency effort to coordinate and stimulate creation of the knowledge, tools, and methods necessary to develop and test nanosensors and to track the fate of engineered nanomaterials in the body, consumer products, the workplace, and the environment.
National Nanotechnology Initiative (NNI) Nanotechnology Signature Initiative on Nanotechnology Knowledge Infrastructure: Enabling National Leadership in Sustainable Design
This is an interagency effort to provide a community-based, solutions-oriented knowledge infrastructure to accelerate nanotechnology discovery and innovation.
National Nanotechnology Initiative (NNI) Nanotechnology Signature Initiative on Nanotechnology Knowledge Infrastructure: Enabling National Leadership in Sustainable Design (NKI)
This is an interagency effort to provide a community-based, solutions-oriented knowledge infrastructure to accelerate nanotechnology discovery and innovation.
NCI - NIH Enterprise Vocabulary Services (EVS) Research Terminology Content, Standards, and Systems Collaboration
The National Cancer Institute (NCI) is collaborating with other NIH institutes to develop terminology content standards extending across basic, translational and clinical research, clinical care, epidemiology, public health, administration, and public information. NCI Enterprise Vocabulary Services provides resources and services to meet NCI, NIH, and other partners' needs for controlled terminology, including the creation, extension, subsetting, mapping, accessing, and publishing of shared standard biomedical terminologies and ontologies.
NCI-NHLBI Cardiotoxicity Working Group
The purpose of this working group is to promote research advances on cancer treatment related cardiovascular toxicity, an area of mutual interest to the National Cancer Institute (NCI) and the National Heart, Lung, and Blood Institute (NHLBI). The staff members collaborate on various initiatives to promote research in this area. The group also collaborates to manage, discuss and share research findings in this research area. Recent initiatives include a funding opportunity announcement (PA-16-035 and PA-16-036). Members also meet regularly to review and assess progress and to consider evolving needs to encourage research to improve cardiovascular outcomes in cancer survivors. Cooperation in selection and funding of cardio-oncology clinical trials is a current topic.
NCI-NHLBI Cohort Collaboration Working Group Meeting
The primary objective of this National Cancer Institute (NCI)-National Heart, Lung, and Blood Institute (NHLBI) Working Group meeting was to inspire cross-disciplinary collaborations on areas of potential common interest. The dialogue focused on how existing NCI- and NHLBI-funded observational studies might be leveraged to explore potential scientific opportunities in cancers, as well as heart, lung, blood, and sleep disorders.
Neural Prostheses Working Group
The Neural Prostheses working group discusses individual efforts by Institutes and Centers in the space of neural prostheses with the goal of identifying gaps through portfolio analyses and IC-specific small business innovation research (SBIR) updates. The working group's first meeting was held on October 31, 2016, and they plan to meet three times a year. At the end of each fiscal year, the working group plans to invite program staff from other agencies (e.g., Defense Advanced Research Projects Agency (DARPA) and the National Science Foundation (NSF)) to compare supported projects in an effort to minimize redundancies and maximize potential innovation.
Neurobiobank Implementation Team
The goal of the Neurobiobank program is to provide human tissues to researchers to enable the identification of pathology and genetics underlying brain disorders. In September 2010, a trans-NIH workgroup was formed to evaluate current approaches and NIH investments in biobanking. Based on consultation with experts within and outside of NIH, the workgroup found that a coordinated approach to biobanking could aid in: (1) increasing consistency of tissue quality through standardized processes; (2) providing consistent standards for data collection and availability; (3) increasing donation by a broad outreach effort to disease advocacy communities; (4) providing greater access to tissue and associated data; and, (5) serving as a home for legacy collections of high quality that lack funding or are currently inaccessible to investigators. In September 2013, five contracts were issued to brain banks to collect, store, and distribute brain tissue for research studies on neurodevelopmental, neurological, and neuropsychiatric diseases. In September 2014, a sixth site was added to the Neurobiobank network. The award to The University of Maryland Brain and Tissue Bank continues a long-funded effort of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) to provide tissues primarily from donors with developmental disorders and healthy controls. The IT infrastructure continues to be funded through a contract. This group works with the six brain and tissue repositories to develop and coordinate a web-based portal for access to these resources, and to provide a simplified process for access to tissues, as well as provide information to the public about the value of brain donation. The Neurobiobank receives and fulfills many requests each month and this demand continues to grow as the community learns about the resource.
Neural prostheses are devices that connect to the nervous system to restore or compensate for lost functions. Because these devices intersect the missions of multiple Institutes and Centers, a working group coordinates NIH activities. The scientific program directors of this working group are also active in the relevant BRAIN Initiative programs.
NIDA Genetics Coordinating Committee
The National Institute on Drug Abuse (NIDA) coordinates genetics research common across the interested NIH Institutes and Centers. The committee holds 1-2 meetings a year with investigators and program staff to discuss research findings.
NIDA-NIAAA Neuroscience Working Group
The purpose of the National Institute on Drug Abuse (NIDA)-National Institute on Alcohol Abuse and Alcoholism (NIAAA) Neuroscience Working Group is to provide a forum to facilitate the discussion and development of neuroscience research programs to understand, prevent, and treat substance abuse and addiction.
NIEHS-NIDDK Joint Postdoctoral Fellowship
This is a joint postdoctoral fellowship program between the Division of Intramural Research at the National Institute of Environmental Health Sciences (NIEHS) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in which two fellowships were funded this year. The fellowships will be funded for up to three years. Two additional fellowships are planned to be awarded again next year.
NIH Adverse Drug Reaction Working Group
The working group includes representatives from 10 Institutes and Centers whose missions relate to exploring the application of new genomic approaches to the prevention and treatment of adverse drug reactions.
NIH Autism Coordinating Committee (ACC)
In 1997, at the request of Congress, the NIH formed an internal trans-NIH ACC to enhance the quality, pace, and coordination of autism research efforts at NIH. The NIH ACC has been instrumental in planning trans-NIH research initiatives to advance the understanding of autism. In addition to program, policy, and communications staff from five Institutes and Centers, the National Institute of Mental Health (NIMH) Office of Autism Research Coordination (OARC) and representatives from NIMH National Database for Autism Research (NDAR) participate in NIH ACC meetings, keeping NIH programs and offices up-to-date on their activities, and coordinating projects of mutual interest. The NIH ACC continually monitors the NIH autism research portfolio and the NIH's progress toward meeting the goals of the Interagency Autism Coordinating Committee (IACC) Strategic Plan for Autism Spectrum Disorder Research.
The mission of the NIH Big Data to Knowledge (BD2K) initiative is to enable biomedical scientists to capitalize more fully on the Big Data being generated by those research communities. With advances in technologies, these investigators are increasingly generating and using large, complex, and diverse datasets. Consequently, the biomedical research enterprise is increasingly becoming data-intensive and data-driven. However, the ability of researchers to locate, analyze, and use Big Data (and more generally all biomedical and behavioral data) is often limited for reasons related to access to relevant software and tools, expertise, and other factors. BD2K aims to develop the new approaches, standards, methods, tools, software, and competencies that will enhance the use of biomedical Big Data by supporting research, implementation, and training in data science and other relevant fields that will lead to:
* Appropriate access to shareable biomedical data through technologies, approaches, and policies that enable and facilitate widespread data sharing, discoverability, management, curation, and meaningful re-use;
* Development of and access to appropriate algorithms, methods, software, and tools for all aspects of the use of Big Data, including data processing, storage, analysis, integration, and visualization;
* Appropriate protections for privacy and intellectual property; and,
* Development of a sufficient cadre of researchers skilled in the science of Big Data, in addition to elevating general competencies in data usage and analysis across the behavioral research workforce.
Overall, the focus of the BD2K initiative is the development of innovative and transforming approaches as well as tools for making Big Data and data science a more prominent component of biomedical research.
NIH Biomedical Information Science and Technology Initiative Consortium (BISTI)
The mission of the BISTI consortium is to make optimal use of computer science and technology to address problems in biology and medicine by fostering new basic understandings, collaborations, and trans-disciplinary initiatives between the computational and biomedical sciences.
NIH Participants: NIGMS, CC, CIT, CSR, FIC, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIMH, NIMHD, NINDS, NINR, NLM, DPCPSI, ODP, OER, OIR, OM, ORS, OSP
NIH Blueprint for Neuroscience Research
The NIH Blueprint for Neuroscience Research is a cooperative effort that pools resources and expertise. The Blueprint supports the development of new tools, training opportunities, and other resources to assist neuroscientists in both basic and clinical research. The Blueprint enables daily collaboration in how NIH conducts neuroscience research and provides a framework for planning and implementing NIH's neuroscience research efforts. The Blueprint does not target specific disorders, rather, it creates common resources. Nervous system disorders appear in many forms including mental, neurological and developmental disorders, alcohol dependence, and drug addictions. Although there are clear differences, many disorders share characteristics of causation and outcome. Tools that are useful in one area – either in the laboratory or the clinic – are likely to be useful in others. One of these tools is the Blueprint Resource Antibodies Initiative for Neurodevelopment. This resource supports the development and distribution of high-quality antibodies for use as markers in neurodevelopment research.
NIH Caribbean American Planning Committee
The mission of the NIH Caribbean American Planning Committee is to foster, facilitate, and advance science that improves health for Caribbean communities within and beyond the region.
NIH Citizen Science Interest Group
The NIH Citizen Science Interest working group is investigating the utility of and furthering the incorporation of citizen science methodologies into biomedical research in a way that maintains NIH's high level of scientific and ethical standards. Citizen science is a collaborative approach to research involving the public, not just as subjects of the research or advisors to the research, but as direct collaborators and partners in the research process. Citizen science takes on many forms and involves a variety of approaches benefiting from the creativity and problem solving skills of the public and from citizen-collected data and insights not obtainable through conventional approaches. This group investigates, shares best practices, and engages in discussions with other agencies and groups promoting citizen science in other fields.
NIH Common Fund Illuminating the Druggable Genome program
The goal of the Illuminating the Druggable Genome Program is to improve our understanding of the properties and functions of proteins that are currently poorly defined within the four most commonly drug-targeted protein families.
NIH Common Fund's Single Cell Analysis Working Group
The NIH Common Fund Single Cell Analysis Working Group is co-led by the National Institute of Mental Health (NIMH) and National Institute of Biomedical Imaging and Bioengineering (NIBIB). The workgroup organized a Single Cell Analysis Investigators Meeting on March 2-3, 2016, to disseminate current research findings in single cell analysis and discuss roadblocks preventing a deeper understanding of the significance of cell-level heterogeneity. The annual investigator's meeting incorporated presentations by four invited keynote speakers and 14 funded investigators, 44 poster presentations, and yielded opportunities to review progress, collaborate, and brainstorm novel ideas. Five scientific sessions were held. Fifteen representatives from different companies including GE, Fluidigm, Life Technologies, and small business innovation research (SBIR)-funded companies participated in a breakout session following the annual meeting. The session focused on identifying a number of important issues related to the need for standards of sample preparation and preservation, sharing of methods, better database resources, and improved single cell technologies and tools.
NIH Disaster Research Response (DR2) Program
The DR2 Project focuses on developing a repository of publicly accessible research data collection tools, surveys and research protocols, a network of trained research responders to be able to help gather environmental health data, and training materials and exercises with federal, state, and local officials, academia, and communities to foster enhanced infrastructure and capacity to understand and address knowledge gaps associated with disasters and other emerging threats.
NIH Flow Cytometry Interest Group
The NIH Flow Cytometry Interest Group, an NIH-affiliated scientific interest group supported by the NIH Office of the Director, provides central information for basic and clinical investigators doing flow and image cytometry at NIH. The group sponsors two meetings a year on the science and technology of cytometry, and is a central clearinghouse for cytometry resources at NIH.
NIH Glycoscience Working Group
This working group assesses the state of glycoscience research and identifies knowledge gaps and research opportunities for future investments. In 2016, the Network implemented an initiative aimed at infusing an experimental medicine approach into ongoing clinical studies across the NIH (PA-16-334), along with a technical assistance webinar that drew a large audience of about 120 participants (NOT-RM-16-027). This initiative invited applications seeking to understand the causal mechanisms underlying interventions to improve behavior change, including adherence behaviors.
NIH Health Literacy Workgroup
The purpose of the NIH Health Literacy Workgroup is to: develop program announcements to fund and manage research projects in health literacy; translate research findings for other NIH staff to inform their practices; and utilize practices from the NIH Office of Communications and Public Liaison to inform program announcement development and research progress.
NIH Hispanic Health Research Scientific Interest Group (SIG)
The NIH Hispanic Health Research SIG was established to foster discussions on Hispanic health-related research topics. Topics include the mechanisms of disease that commonly affect Hispanics and other populations, interventions to prevent chronic diseases or their complications, translational and implementation research, clinical trials, health education and communication, health services-related research, social sciences, bioethics, health policy, and more. These discussions aim to translate knowledge and research into the improvement of the health of Hispanics and the general population, identify new areas of research as well as potential trans-NIH or trans-Department of Health and Human Services collaborations.
NIH Human Subjects Protection Liaison Committee
The committee was established by the Office of Extramural Programs to provide the Office of Extramural Research with input and recommendations on issues involving the protection of human subjects in NIH-sponsored research.
NIH Institute and Center International Representatives Forum
The Fogarty International Center (FIC) established the NIH Institute and Center International Representatives Committee (ICREPS) to provide a standing official forum for trans-NIH coordination and development of NIH international activities. ICREPS includes at least one designated representative from each of the 27 Institutes and Centers of the NIH. The ICREPS Committee meets periodically, and the group maintains an active email listserv, providing NIH components with an easily accessible trans-NIH platform to share information and solicit input on a wide range of NIH international initiatives and policy matters. The Centers for Disease Control and Prevention (CDC), U.S. Agency for International Development (USAID), U.S. Department of State, and other U.S. Government agencies have an open invitation to attend the bimonthly ICREPS meetings.
NIH Institute and Center Liaison Language Access Plan (LAP) Committee
The LAP committee leads the process of implementing and sustaining Language Access within their respective Institutes and Centers. The committee is responsible for completing a comprehensive needs and capacity assessment for their respective Institutes and Centers and NIH subcomponents in accordance with the NIH LAP Plan. The committee identifies possible universal barriers and shares best practices for implementation and sustainability to ensure compliance with Executive Order 13166 and related guidance.
NIH Interagency Coordination mHealth Workgroup
The NIH Interagency Coordination mHealth Workgroup is working to develop a research basis for mHealth. This includes several Funding Opportunity Announcements in fiscal years 2015 and 2016.
NIH Language Access Steering Committee
This committee created a strategy by which NIH ensures that individuals who are limited-English proficient have meaningful access to NIH programs and activities. Their work helps to bring NIH into compliance with civil rights laws and guidance and ensures that the agency's work is more inclusive of underrepresented populations, particularly those that may face barriers to accessing NIH because of a lack of a knowledge of English. The Steering Committee engineered the NIH Language Access Plan (LAP) and continues to focus on guiding the Institutes and Centers toward full implementation of the Plan.
NIH Medical Rehabilitation Coordinating Committee
Pursuant to Public Law 101-613, the NIH Director established the Medical Rehabilitation Coordinating Committee. The Coordinating Committee makes recommendations to the Director of the Institute and the Director of the Center with respect to the content of the research plan and the activities of the Center that are carried out in conjunction with other components of NIH and with other Federal Government agencies. The Coordinating Committee includes the Director of the Center, the Director of the Institute, and the Directors of the National Institute on Aging (NIA), the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the National Heart, Lung, and Blood Institute (NHLBI), the National Institute of Neurological Disorders and Stroke (NINDS), other national research institutes, and representatives of other agencies of the Federal Government as determined by the NIH Director. The Coordinating Committee is chaired by the Director of the Center.
NIH MicroRNA (miRNA) Interest Group
The group shares protocols and papers online and organizes invited seminar speakers and an annual poster session.
NIH Nanoscale Science, Engineering and Technology (NSET) Subcommittee Activities
In 2014, NIH was appointed as the agency co-chair of NSET by the White House Office of Science and Technology Policy. The goal of this working collaboration is to ensure strong coordination of activities and initiatives across NIH institutes and in response to the Subcommittee's and Office of Science and Technology Policy's management of the National Nanotechnology Initiative.
NIH Nutrition Research Task Force
The NIH Nutrition Research Task Force (NRTF) was established to coordinate and accelerate progress in nutrition research across the NIH and guide the development of the first NIH-wide strategic plan for nutrition research for the next 10 years. The NRTF will draw from experts across multiple fields, as nutrition affects both a wide range of diseases — including diabetes, cancer, obesity, and heart disease — as well as overall health and normal development.
NIH Obesity Research Task Force
The NIH Obesity Research Task Force was established to accelerate progress in obesity research across NIH in view of the importance of the obesity epidemic as a public health crisis. The task force has been instrumental in fostering trans-NIH collaboration on obesity research, including basic, clinical, and population studies. The task force also sponsors an NIH seminar series on obesity research topics.
NIH Pain Consortium
The NIH Pain Consortium was established to enhance research on pain and promote collaboration among researchers across the NIH Institutes and Centers that support programs and research activities addressing pain. These activities include research on sensory and basic mechanisms, as well as the emotional and biobehavioral aspects of pain. Age, sex, hormones, gender, ethnicity, and genetics all play a role in pain response and perception. The goal is that better pain management will result from increased knowledge of basic pain mechanisms.
NIH Planning and Evaluation (P&E) Officers Committee
The NIH P&E Officers Committee serves: to advise and support the NIH on science policy issues affecting the biomedical and behavioral research enterprise; to collaborate with the NIH Office of the Director and scientific staff to develop and coordinate each Institute's planning, evaluation, and reporting process; and as a key resource for the exchange and dissemination of information relevant to NIH policies, procedures, and strategic objectives.
NIH Proteomics Interest Group (ProtIG)
The ProtIG is an NIH Special Interest Group that organizes seminars and workshops in relevant areas of proteomics, including presentations on separation and protein identification methods, determination of post-translational modifications, protein-protein interactions, bioinformatics, and data management. A monthly seminar series is held to foster interaction among the Institutes and Centers and the research community.
NIH Robotics Working Group
The Robotics Working Group engages program officers across NIH with an interest in promoting robotics to address health needs. Discussions address topics related to planning trans-NIH initiatives, co-funding grants and contracts, and participating in joint site visits to mutually funded investigators. This working group is also linked to the efforts of the National Robotics Initiative (NRI) that held a Principal Investigators meeting in November 2016. Although the NRI Memorandum of Understanding has ended, NIH program officials continue to engage with other government colleagues.
NIH SBIR/STTR Reauthorization Implementation Group
This working group provides input and assistance to the NIH Office of the Director for implementation of the SBIR/STTR Reauthorization Act of 2011.
NIH Scientific Interest Group
Trans-NIH scientific interest groups are assemblies of scientists with common research interests.
NIH Scientific Program and Review Interest Group (SPRIG)
The overarching goal of SPRIG is to support the idea of continuing to learn and to learn from one another, with the focus being program and review administrative policies at the NIH. To support career development and enhance networking, SPRIG creates training activities of general and special interest on an informal basis.
NIH Single IRB Evaluation and Metrics Sub-Committee
This sub-committee identifies criteria and metrics to evaluate the Single Institutional Review Board (IRB) Policy, including developing short, intermediate, and long term evaluation questions as well as considering the collection of data elements.
NIH Single IRB Policy Implementation Committee
This group assists NIH leadership to implement the NIH Policy on the Use of a Single Institutional Review Board (IRB) for multi-site research, which will be effective in September 2017.
NIH Single IRB Policy Implementation Exceptions Sub-Committee
This subcommittee identifies the expertise needed for a committee that will review requests for exceptions from the Single Institutional Review Board (IRB) policy and makes determinations that can be used as precedent for subsequent decisions.
NIH Single IRB Policy Implementation Guidance and Training Sub-Committee
To successfully implement the Single Institutional Review Board (IRB) Policy, this sub-committee develops guidance and training materials to help NIH staff assist applicants and manage multi-site human subjects research funded by the NIH.
NIH Social Media Collaboration Group
This working group connects staff responsible for managing the NIH Institute and Center social media outlets such as Facebook, Twitter, and YouTube. The collaborative coordinates its activities through monthly meetings where best practices, government regulations and collaborative strategies are presented and discussed. The membership represents every NIH Institute and Center and routinely collaborates through an NIH Listserv that is used to share postings that participants can use on their own outlets and through NIH Yammer. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) currently leads the group planning and meetings on behalf of NIH Office of Communications and Public Liaison.
NIH Steering Committee on Trans-Institute Angiogenesis Research Program (TARP)
The TARP Steering Committee encourages and facilitates the study of the underlying mechanisms controlling blood vessel growth and development, to identify specific targets and to develop therapeutics against pathologic angiogenesis in order to reduce the morbidity due to abnormal blood vessel proliferation in a variety of disease states, and to better understand the process of angiogenesis and vascularization to improve states of decreased vascularization.
NIH Strategic Communications Planning Project
The NIH Office of the Director leads an ongoing strategic communications planning project to maximize the impact of communications across the agency. Several years ago, the NIH Associate Director for Communications and Public Liaison organized the effort to enhance communication efforts, improve efficiencies, and make it easier for NIH's many stakeholders to access information about NIH. To date, the Institutes and Centers have agreed on a common "mark" for an NIH logo, thus reducing redundancy and costs of producing hundreds of independent logos each time a new program began. Also, there is now more coordination among social media sites across NIH, as well as exhibits at professional conferences. Currently, the Institute and Center communications offices are exploring optimal collaborations to improve efficiencies and lower cost through joint warehousing of materials and product-sharing. In 2015, the Institutes and Centers will embark on a new round of discussions to further enhance strategic communications, increase trans-NIH collaboration, and improve efficiencies.
NIH Tuberculosis (TB) Working Group
The TB Working Group provides a forum for sharing information about NIH-specific TB projects, including both ongoing and proposed research, including extramural funding initiatives. In addition, the working group fosters continual open communication about TB research being conducted across NIH and maintains a consistent message about the importance of NIH intramural and extramural TB research. It also provides an avenue for the introduction of new technology programs of interest and importance for TB research (such as the "human on a chip"). The working group invites guests/speakers from outside NIH and convenes invitations for teleconference participation to other U.S. Government agencies including the Centers for Disease Control and Prevention (CDC) and the U.S. Agency for International Development (USAID).
NIH Working Group on Down Syndrome
The National Institute of Child Health and Human Development (NICHD) leads the Trans-NIH Down Syndrome Working Group, which plays a critical role in the Down Syndrome Consortium--a collaboration to foster communication and idea-sharing among the NIH, individuals with Down syndrome and their families, national organizations interested in Down Syndrome, and pediatric and other organizations. During Down Syndrome Awareness Month in September, as well as at other times during the year, the NICHD provides messages and materials to the other members of the Working Group and Consortium to help promote DS-Connect(R), the Down Syndrome Registry, and online resource for people with Down Syndrome and their families. These promotions, mostly via social media and online community outreach, help to drive people to the DS-Connect(R) website to learn more about the registry and to sign up to participate.
NIH Working Group on Emergency Medicine
The trans-NIH Working Group on Emergency Care Research is an ongoing group under the leadership of the Office of Emergency Care Research, in the National Institute of General Medical Sciences. It meets to share and coordinate activities related to emergency care research and research training.
NIH Working Group on Women in Biomedical Careers
The Working Group on Women in Biomedical Careers is a trans-NIH effort to address barriers for women in science and to develop innovative strategies to promote entry, recruitment, retention, and sustained advancement of women in biomedical and research careers. The Working Group collaborates with the NIH Institutes and Centers to promote tangible changes to institutional policies in the NIH intramural and extramural communities.
NIH-BMGF Child Health and Development Working Group
The NIH-BMGF Child Health and Development Working group is a cooperative partnership to develop interventions to reduce major global health burdens by launching milestone-driven projects on an agreed set of priorities, including maternal and infant nutrition and healthy cognitive development in children. These collaborative projects facilitate data sharing and expertise.
NIH-Networking Information Technology Research and Development Program (NITRD) Consortium
The NIH-NITRD operates under the aegis of the NITRD Subcommittee of the National Science and Technology Council's Committee on Technology. The Subcommittee, made up of representatives from each of NITRD's member agencies, provides overall coordination for NITRD activities.
NIH-Pfizer Centers for Therapeutic Innovation (CTI) Steering Committee
The NIH-Pfizer (CTI) collaborative program is designed to help bridge the gap between early scientific discovery and its translation into new medicines through novel public-private collaboration. The CTI network includes 25 academic institutions, six foundations, and now NIH. NIH intramural researchers selected for CTI projects will have identified-disease related pathways or mechanisms as potential therapeutic targets that culminate in Phase I clinical trials to demonstrate proof-of-mechanism. The collaboration is coordinated by the National Center for Advancing Translational Sciences (NCATS), with a joint NIH-Pfizer Steering Committee governing the collaboration. The Joint Steering committee includes members from several institutes within the NIH. This program consists of meetings and workshops for the NIH intramural community.
NIH-South Africa Medical Research Council (MRC) Program
The NIH-South Africa MRC initiative is a collaborative biomedical research program established under a Memorandum of Understanding between NIH and the MRC. It currently involves eight NIH Institutes and Centers. Three NIH Requests for Applications have been published as part of this initiative to invite R01, R21, and U01 grant applications from interested teams of U.S. and South African investigators. The focus of these funding opportunity announcements is HIV/AIDS, tuberculosis, and other HIV-associated co-morbidities including cancer. Following NIH peer review, highly meritorious applications will be funded utilizing resources from both NIH and the MRC. Additional activities under the initiative include research training, the provision of expert advice and joint scientific consultations, the first of which was convened in Durban, South Africa, in 2013. Additional joint research programs also are being considered for inclusion within this collaborative initiative.
NIH-TÜBITAK Collaborative Biomedical Research Program
This bilateral program between the NIH and the Scientific and Technological Research Council of Turkey (TUBİTAK) was established in January 2013 with a Letter of Intent to collaborate. The purpose of this collaboration is to foster, stimulate, and/or expand basic, translational, behavioral and applied research that will advance scientific discovery and engage U.S. and Turkish researchers working collaboratively. The National Institute of Allergy and Infectious Diseases (NIAID) has been asked to collaborate on Hepatitis B/delta virus, human microbiome, and genetic predisposition to infectious diseases. In October 2014, NIAID helped organize and convene a Scientific Workshop on Genetically-Based Immune Disorders. This was followed by a TUBITAK funding opportunity to support U.S.-Turkish research collaboration. Two grants were approved involving Turkish and NIH co- investigators, as follows: 1) Gulhane Medical Academy of Medicine and NIH/National Human Genome Research Institute (NHGRI) - "Screening Autoinflammatory Diseases in Turkish Rheumatology Centers- to Identify Novel Mutations and Gene Functions"; and 2) Hatcettepe University and NIH/National Institute of Allergy and Infectious Diseases (NIAID)- "Investigations of Patients with Innate Immune Defects, Combined Immunodeficiencies and Diseases of Immunodysregulation."
NIH/FDA Leadership Council’s Workgroup on Preclinical Toxicology
The NIH/Food and Drug Administration (FDA) Leadership Council was established to ensure that regulatory considerations form an integral part of biomedical research planning and that the latest science is integrated into the regulatory review process. The Preclinical Toxicology Workgroup is one of six smaller subcommittees of the larger Council.
NIH/Gates Malaria Working Group
Within the purview of the NIH/Gates collaboration, the National Institute of Allergy and Infectious Diseases (NIAID) is collaborating with the National Institute of Biomedical Imaging and Bioengineering (NIBIB) on malaria diagnostics.
NIH/Gates Zika Working Group
Within the purview of the NIH/Gates collaboration, the National Institute of Allergy and Infectious Diseases (NIAID) is collaborating with the National Institute of Child Health and Human Development (NICHD) on Zika virus.
NTP Literature-Based Evaluations of Shift Work at Night, Light at Night and Circadian Disruption
The National Institute of Environmental Health Sciences (NIEHS) and that National Heart, Lung, and Blood Institute (NHLBI) collaborated on an evaluation team to provide scientific input on the National Toxicology Program's (NTP) (Office of Health Translation and Assessment and the Office of the Report on Carcinogens) literature-based evaluations of cancer and non-cancer effects of Shift Work at Night, Light at Night and Circadian Disruption. Conferences calls with external scientific experts were convened in 2014 and 2015, and a workshop is planned for 2016.
Nutrition Research Coordinating Committee (NRCC)
The Nutrition Research Coordinating Committee (NRCC) was established by the NIH Office of the Director in 1975 to improve communication and research coordination of nutrition activities within the NIH and across the federal government. Today it provides an open forum for members to discuss current and future nutrition research challenges and opportunities. The NRCC has broad representation from the NIH Institutes and Centers. In addition, liaisons from other federal offices and agencies also participate. The NRCC meets monthly, alternating between intra-NIH and interagency meetings. NRCC membership is open to any federal staff member interested in carrying out any trans-NIH or trans-agency nutrition research efforts. Meetings are chaired by the Director of the National Institute of Diabetes and Digestive and Kidney Disease's Office of Nutrition Research. Scientific seminars and discussions are featured during the NRCC meetings as a means of disseminating information on nutrition research efforts and to stimulate new research in priority areas.
NIH Participants: NIDDK, CC, CIT, CSR, FIC, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NICHD, NIDA, NIDCD, NIDCR, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR
HHS OPDIVs Participants: FDA, AHRQ, CDC, HRSA
Other Participants: OS, DoD, IHS
OppNet Steering Committee
The OppNet Steering Committee provides guidance and final approval for Funding Opportunity Announcement concept clearance and funding decisions.
Outcome Study of the NIH Loan Repayment Programs Working Group
This group reviews and advises on various study issues , including design, sampling, as well as interpreting and applying results to guide program improvement.
Outcomes Effectiveness Research Interest Group (OER-IG)
Outcomes and effectiveness research is a field that describes, interprets, and predicts the effect of health-care interventions on endpoints that matter to patients, families, providers, payers, purchasers, and society in general. NIH has long supported a diverse portfolio of such research, including observational and randomized studies comparing different strategies to prevent, diagnose, treat, and monitor many diseases and conditions. With increased public interest, as evidenced by the Congressional legislation that created the Patient-Centered Outcomes Research Institute (PCORI) and by NIH's newly launched Common Fund efforts to support pragmatic clinical trials and to harness the power of "big data" there is growing need for effective trans-NIH communication. The Trans-NIH OER-IG, a successor to the Trans-NIH Comparative Effectiveness Research Coordinating Committee, will function as a forum for institutes and centers to discuss matters of interest to the community. The OER-IG plans to convene 8 to 10 meetings annually, serve as a forum for information exchange, and foster a stimulating learning environment but will not not engage in policy development.
Pacific Basin Consortium for Environment and Health
The National Cancer Institute (NCI) is working with the National Institute of Environmental Health Sciences (NIEHS) and the Pacific Basin Consortium for Environment and Health (PBC). PBC provides a forum for individuals and organizations with diverse professional expertise and geographic backgrounds to come together and discuss the most pressing environment and health issues of our time, engage in cooperative research, and develop and disseminate innovative strategies for addressing these issues and creating sustainable, affordable alternatives.
Pancreatic Ductal Adenocarcinoma (PDAC) Progress Working Group
In response to the Recalcitrant Cancer Research Act of 2012, the National Cancer Institute (NCI) formed the Pancreatic Ductal Adenocarcinoma or PDAC Progress Working Group to advise the NCI on the effectiveness of its scientific framework to combat the disease. The framework contains 4 initiatives: the relationship between PDAC and diabetes mellitus of recent onset; biomarker and imaging studies to identify those at high risk of PDAC; new immunotherapies for PDAC; and development of therapeutics that target the Ras oncogene.
Pandemic Prediction and Forecasting Science and Technology Working Group (PPFST)
This interagency working group, directed by the Office of Science and Technology Policy, is responsible for analyzing the state of infectious disease modeling and prediction and facilitating coordination among numerous federal agencies.
Participant Protection and Data Management Steering Committee
This committee advises the Senior Oversight Committee on the programmatic and policy needs and opportunities for the implementation of NIH’s data sharing policy for genome-wide association studies. The committee has focused on developing common processes and forms for NIH's Data Access Committees and provided a forum for discussing implementation issues.
Pediatric Adverse Event Terminology Harmonization Working Group
The Pediatric Adverse Event Terminology Harmonization Working Group is one of several working groups that function under the general National Institute of Child Health and Human Development (NICHD) - National Cancer Institute (NCI) Terminology Harmonization Initiative. Working groups exist for adverse events, neonatology, perinatology, placental biology, rheumatology, endocrinology, infectious diseases, nephrology, and hematology/oncology. Each working group consists of one or two leads plus subject matter experts in terminology, informatics, and the specific pediatric medical specialty. The Adverse Event Working Group was the most diverse and included experts from a broad range of pediatric subspecialists, including surgeons. The work of this group has resulted in the harmonization of hundreds of terms that filled gaps and extended the useful range of describing pediatric events. The terms were rapidly adopted into the Medical Dictionary for Regulatory Affairs (MedDRA) and incorporated into the NCI Enterprise Vocabulary Services webpage to be globally accessible.
Physician-Scientist Workforce Implementation Group
This group reviews and recommends plans to implement the recommendations of the Physician-Scientist Workforce Working Group, a component of the Advisory Committee to the Director of NIH.
Planning Group for Challenges in GxE Research in the Behavioral and Social Sciences
The goal of this group is to identify key challenges in gene-environment interaction (GxE) research that cross content area and Institute and Center interests, and identify ways to advance science in those areas. The current topic of interest is pooling and data harmonization for behavioral and social science studies with the goal of increasing sample sizes for GxE analyses. The planning group is planning a series of educational webinars on this topic.
Post-traumatic Stress Disorder (PTSD)/Traumatic Brain Injury (TBI), Suicide Prevention National Research Action Plan (NRAP) Workgroup
A 2012 White House Executive Order, emphasizing support of Service Members, Veterans, and their families as a top priority, called for an urgent increase in the Departments of Health and Human Services (HHS), Defense (DoD), and Veterans Affairs (VA) research coordination to address the problems of PTSD, TBI, and suicide. Section 5 of this Executive Order requested a National Research Action Plan (NRAP) to develop biomarkers, define the pathophysiology, and develop new treatments for PTSD. HHS charged the National Institute of Mental Health (NIMH) to lead this effort, along with the National Institute of Neurological Disorders and Stroke (NINDS) leading a parallel effort for TBI, and both Institutes worked closely with the VA and DoD. The NRAP was published in 2013. Prior investments integrating the molecular, genomic, and brain circuitry changes that give rise to PTSD in the context of environmental factors provide the requisite foundation to respond to this White House request for biomarkers for risk prediction, as well as new targets for medications, and other therapies to treat PTSD. This investment has the potential to revolutionize the care for individuals at high risk for PTSD and prevent the development of chronic, complex treatment-resistant PTSD. The agencies meet weekly on these efforts and produce quarterly progress reports.
Precision Medcicine Initative (PMI "All of Us") and Families Working Group
The Working Group assessed strategies for incorporating families in the PMI to include all age ranges, identified a number of examples of how this can be done and resources for PMI efforts, and highlighted critical issues that will need to be addressed as the initiative moves forward.
PregSource Management Team
In consultation with the PregSource Partners, the PregSource Management Team finalizes selection of topics for inquiry; works closely with PregSource contractor to develop sites; assures compliance with applicable NIH policies and procedures, including Institutional Review Board approval; develops content for online and app-based versions; oversees outreach efforts to bolster participation; monitors overall function and usage of PregSource; participates in analysis and interpretation of data; and reports results in publications and presentations.
Prevention Research Coordinating Committee (PRCC)
This committee serves as a venue for exchanging information on recent scientific advances in disease prevention; examining the impact of new policies on research; planning new or discussing ongoing initiatives; and highlighting program accomplishments. As a trans-NIH, trans-agency committee, the PRCC provides a broad perspective on the current state-of-the-science and actively disseminates information about prevention-related activities sponsored by federal and non-federal organizations to the NIH Institutes and Centers.
NIH Participants: ODP, CC, FIC, NCATS , NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIMH, NIMHD, NINDS, NINR, NLM, OBSSR, ORWH
HHS OPDIVs Participants: AHRQ, CDC
Other Participants: Office of the Secretary -- Office of Disease Prevention and Health Promotion
Report on Carcinogens (RoC) Evaluation of Five Selected Viruses: Epstein-Barr virus (EBV), human immunodeficiency virus type 1 (HIV-1), human T-cell lymphotropic virus type 1 (HTLV-1), Kaposi sarcoma-associated herpesvirus (KSHV), Merkel-cell polyoma
The National Institute of Environmental Health Sciences (NIEHS) and the National Cancer Institute (NCI) collaborated on preparing the RoC evaluation of five selected virus (EBV, HIV-1, HTLV-1, KSHV, and MCV) for possible listing in the RoC. The RoC is a congressionally mandated, science-based, public health report that identifies substances in our environment that are cancer hazards for people living in the United States.
Research Prioritization Task Force of National Action Alliance for Suicide Prevention (NAASP)
Founded in September 2010, the NAASP is a public-private partnership designed to advance the National Strategy for Suicide Prevention in the United States. The NAASP's Research Priority Task Force (RPTF) is charged with developing a process to prioritize suicide prevention research efforts and consider ways to integrate science and service to ensure that suicide deaths decrease significantly within the next decade. The RPTF released the Nation's first suicide research agenda, “A Prioritized Research Agenda for Suicide Prevention: An Action Plan to Save Lives.” The research agenda includes an overarching goal to advance suicide prevention research more rapidly, seeking ways to reduce suicide deaths and attempts by 20% in five years and by 40% or greater in ten years. In 2015, the RPTF produced the "U.S. National Suicide Prevention Research Efforts: 2008-2013 Portfolio Analyses." The analyses revealed that investments in suicide research are severely lagging, but there is a growing knowledge base of intervention research. In 2016, the NIH Office of Disease Prevention supported the “Pathways to Prevention Workshop, Advancing Research to Prevent Youth Suicide in 2016,” which further refined methodological challenges and data linkage needs relevant to multiple NIH Institutes. The National Institute of Mental Health (NIMH) developed a request for information relevant to this workshop, and a federal partners meeting in the spring of 2017 will consider additional actions in response to the workshop recommendations.
Science of Behavior Change Working Group
The overall goal of the program is to transform behavioral intervention designs by implementing the experimental medicine approach to behavior change research. Projects focus on identifying and validating targets in the three specific behavioral domains of self-regulation, stress reactivity and stress resilience, and interpersonal and social processes. In 2015 a series of 4 Requests for Applications were issued (RFA-RM-14-017, RFA-RM-14-018, RFA-RM-14-019, RFA-RM-14-020). Nine awards were made from these solicitations, including one data coordinating center, and these formed the Science of Behavior Change Research Network. These groups convened at a kick-off meeting on December 3, 2015.
SCOPE (Spinal Cord Outcomes Partnership Endeavor)
The mission of SCOPE is to enhance the development of clinical trial and clinical practice protocols that will accurately validate therapeutic interventions for spinal cord injury leading to the adoption of improved best practices. One of the goals is to facilitate communication and coordination of effort between basic scientists, clinical researchers, academic institutions, industry, government agencies, and not-for-profit foundations.
Sleep and Obesity Working Group
The goal of this working group is to identify opportunities to advance the understanding of the contribution of sleep and circadian deficiency to the etiology of obesity, to mechanisms underlying abnormalities in energy balance and metabolism, and to the ability to lose weight and maintain weight loss.
Special Populations Research Forum
This forum provides a trans-NIH platform for sharing and examining programs and initiatives designed to enhance and accelerate the development of research careers of individuals from underrepresented (racial/ethnic and health disparity) populations. The forum ultimately seeks to consider a broad range of activities pertinent to the conceptualization, implementation, review, administration, management, and evaluation of research, training, and outreach of programs based in institutions serving underrepresented populations.
SRO Technical Competencies Subcommittee (STCS)
The Scientific Review Officer (SRO) Technical Competencies Subcommittee of the Review Policy Committee is a group of dedicated, experienced SROs that defines technical competencies, key behaviors and proficiency levels and identifies and enhances associated training for the NIH scientific review community to provide a common foundation to allow SROs to address their training needs.
Structured Data Capture (SDC) Forms Working Group
The Structured Data Capture (SDC) initiative is sponsored by the Department of Health and Human Services, Office of the National Coordinator (ONC), as part of the Standards and Interoperability Framework initiative, a collaborative program of public and private sectors involved in health information exchange. The SDC mission is to develop and validate data element and case report form (CRF) metadata and data standards-based data architecture so that a structured set of data can be accessed from electronic health records and stored for merger with comparable data for other relevant purposes. The SDC working group evaluated and selected two International Organization for Standardization (ISO) standards as the starting point: ISO/IEC (International Electrotechnical Commission) 19763-13 (Forms metamodel) and ISO/IEC 11179 (Metadata Registries and Data Elements metamodel), respectively. These are related because data elements form the basis for questions on forms. The National Cancer Institute (NCI) helped develop version 1 of the SDC profile and implementation guide for these standards and we have been monitoring the development and testing of version 2. Through the SDC working group, NIH also participates in the review and formation of the SDC Data Element profile, the Fast Healthcare Interoperability Resources (FHIR) Questionnaire and FHIR Data Element resources.
Systems Biology Scientific Interest Group (SysBioSIG)
SysBioSIG sponsors activities exploring the diverse aspects of systems biology. This interest group hosts seminars and workshops to exchange ideas between scientists conducting research in this field.
TGF-beta Superfamily Interest Group
The Tumor Growth Factor (TGF)-beta superfamily occupies a central position in the signaling circuits that control cell growth, differentiation, and death. Seminal work has resulted in a better appreciation of the integration of TGF-beta pathways into signaling networks at large and its disruption in a wide variety of human disorders. While TGF-beta remains elusive in terms of a complete understanding of its multifunctional modes of action, its potential as a therapeutic target in many pathological settings is promising. The TGF-beta Superfamily Interest Group keeps abreast of advances in the field of TGF-beta superfamily research and in the global ramifications when TGF-beta signaling goes awry in diseases such as cancer, diabetes, obesity, immunological disorders, and pathological fibrosis. The group also serves as a platform for dissemination of TGF-beta-related reagents and expertise at NIH.
The ABCD Collaborators Group
The Adolescent Brain and Cognitive Development (ABCD) Study is the largest long-term study of brain and cognitive development in children across the United States. Findings from the ABCD Study will greatly increase our understanding of environmental, social, and genetic factors that affect brain and cognitive development and that can enhance or disrupt a young person's life trajectory. The ABCD Study is funded by 13 cooperative agreements, requiring substantial NIH involvement in the management of the study. The ABCD Collaborators Group consists of NIH staff from the 8 participating Institutes, Centers, and Offices, some of whom are involved in various workgroups within the study. The ABCD Collaborators Group meets monthly to ensure that all participating Institutes and Centers are kept abreast of the activities of these various workgroups, the progress on the study, and any issues that need to be resolved.
The Blueprint Neurotherapeutics Network (BPN)
The NIH BPN was established by the NIH Blueprint for Neuroscience (a collaborative effort among 16 NIH Institutes, Centers, and Offices) to bridge the gap in drug development between academic and industry research and develop novel drugs to treat nervous system disorders. The network offers neuroscience researchers a "virtual pharma" to develop promising hit compounds, from chemical optimization through phase I clinical testing. Participants in the BPN receive funding to conduct bioactivity and efficacy testing, as well as access to NIH-contracted drug development services and consultants who have extensive experience in drug discovery. The BPN mission spans the gamut of disorders of the nervous system and initial disease targets include Alzheimer's disease, Parkinson's disease, stroke, major depression, narcolepsy, deafness, and vision loss.
The Breast Cancer & the Environment Research Program (BCERP)
The BCERP has been jointly funded by the National Institute of Environmental Health Sciences (NIEHS) and the National Cancer Institute (NCI) since 2003. The program is currently in its second iteration and will begin its third phase in September 2015. The BCERP supports transdisciplinary research on the interactions of environmental factors (including chemical, physical and social environmental) with genetic factors during windows of susceptibility throughout a woman's life that potentially influences breast cancer risk. Each research project is required to partner with a local community-based or advocate organization focused on breast cancer. In addition, the program supports an overall Coordinating Center to provide leadership and logistical support for consortium-wide activities.
The Initiative for Multipurpose Prevention Technologies (IMPT) Supporting Agency Collaboration Committee (SACC)
The SACC leads efforts to increase collaboration and coordination among supporting agencies (i.e. funders) around Multipurpose Prevention Technologies (MPT) development activities. The SACC provides guidance to the field by helping determine how to best deploy limited resources, facilitate funding to support critical work, minimize duplication of effort and rationalize a complex field that crosses disciplines and funding streams. With limited resources, the SACC will help streamline investment in MPT development. The SACC has engaged representatives from: the Bill & Melinda Gates Foundation, Department for International Development, Indian Council for Medical Research (ICMR), Mary Wohlford Foundation, the National Institute of Child Health and Human Development (NICHD), the National Institute of Allergy and Infectious Diseases (NIAID), the NIH Office of AIDS Research, Wellcome Trust, and U.S. Agency for International Development (USAID). In April 2014, the SACC held the first in person MPT Supporting Agency Coordination Planning Meeting to discuss potential frameworks for coordination among MPT supporting agencies.
The Pain Special Interest Group (Pain SIG) Seminar Series
The Pain SIG seminar series is a monthly lecture series that invites national and international speakers as well as intramural scientists in the area of pain and associated disorders to present their findings to an audience of NIH staff and scientists in local research universities and institutes. These interactions foster dissemination of new knowledge, facilitate interaction between scientists and foster collaborations.
Therapeutics Discovery Project (TDP) Team
The TDP team explores new therapeutic uses for proprietary drug candidates (agents) across a broad range of human diseases. The program matches agents and associated data from eight pharmaceutical company partners with the best ideas for new therapeutic uses from the research from the biomedical research community. While the National Center for Advancing Translational Sciences (NCATS) issued the Funding Opportunity Announcements for this program, a Project Team composed of 14 NIH Institute and Center Science Officers/Project Scientists and Program Officials advise NCATS on proposed new therapeutic uses of the agents in disease-specific areas and make program recommendations on the pre-clinical validation and clinical feasibility of proof-of-concept clinical trials.
Tobacco and Nicotine Research Interest Group (TANRIG)
TANRIG was formed in January 2003 to increase collaboration, coordination, and communication of tobacco- and nicotine-related research among NIH Institutes and Centers, as well as with other relevant agencies within the Department of Health and Human Services.
The Tox21 initiative, formed through a Memorandum of Understanding between the National Institute of Environmental Health Sciences' (NIEHS) National Toxicology Program (NTP), the National Center for Advancing Translational Sciences (NCATS), the U.S. Environmental Protection Agency (EPA), and the U.S. Food and Drug Administration (FDA), was formed to develop high-throughput screening tests that measure cellular harm caused by environmental chemicals. The goals of the Tox21 initiative are to: identify patterns of compound-induced biological response in order to characterize toxicity and disease pathways; facilitate cross-species extrapolation; model low dose extrapolation; prioritize compounds for more extensive toxicological evaluation; and develop predictive models for biological response in humans.
Trans NIH Program Leadership Committee (PLC)
The PLC is the principal trans-NIH committee for the development, implementation, and evaluation of program policies and procedures and for advising NIH leadership on programmatic issues. The mission of the PLC is to advise on issues related to the processes of leading and managing the NIH scientific programs including program coordination for the implementation of trans-IC initiatives, focusing on program policy and its implementation by program administrators. The PLC is charged to help NIH accomplish its mission by anticipating and avoiding difficulties with the implementation of new policies and procedures as well as solving problems in existing operations.
Trans NIH Working Group on Point of Care Technologies (POCT-WG)
The purpose of the working group is to promote collaboration amongst NIH program staff from various Institutes and Centers who work on or have an interest in various aspects of point of care technologies/near patient diagnostic testing and treatment. With the current healthcare themes around immediate testing and treatment, precision medicine, and technologies for use in limited resource areas, now is the perfect time to explore what efforts are being considered or conducted across NIH and beyond.
Trans-Agency Early-Life Exposures and Cancer (TAEEC) Working Group
The TAEEC Working Group's mission is to promote the integration of early-life events and exposures, including maternal, paternal, in utero, perinatal, childhood, pre-adolescent, and adolescent events/exposures into public health cancer research, control, prevention, and policy strategies to reduce the cancer burden in the United States and globally.
Trans-NIH Advisory Group (TAG), Therapeutics for Rare & Neglected Diseases (TRND) Program
The TRND Program receives proposals to collaborate on preclinical therapeutic development projects from a variety of external entities. Unlike other disease/organ system-centric Institutes and Centers, the TRND Program within the National Center for Advancing Translational Sciences (NCATS) may receive proposals across the spectrum of disease areas. The TAG is comprised of representatives from across a number of other Institutes and Centers to allow TRND Program Staff to receive disease/biology area-specific insight into the candidate proposals under consideration
Trans-NIH Alzheimer's Disease Work Group
The Trans-NIH Alzheimer's Disease Work Group coordinates Alzheimer's Disease extramural research across relevant NIH Institutes and Centers. The main topic in 2013 was the development of milestones for the National Alzheimer's Project Act strategy and action items. The National Institute on Aging led the milestone development effort and consulted with representatives from other NIH institutes through the Trans-NIH Alzheimer's Disease Research Working Group. This Working Group collaborates on important opportunities to build upon and leverage Department of Health and Human Services' programs and other federal efforts to help change the trajectory of Alzheimer's Disease and related dementias.
Trans-NIH American Indian and Alaska Native Health Communications and Information Work Group
Since 2005, the Trans-NIH American Indian and Alaska Native Health Communications and Information Work Group has provided a forum for health education and communications staff from across NIH. The work group focuses on sharing strategies and learning effective approaches to developing and disseminating health information about American Indian and Alaska Native communities. The goal of the work group is to further educate NIH health communication professionals and share information on socio-cultural issues and other issues that may influence the development and dissemination of effective health communication efforts.
NIH Participants: NIAMS, CC, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, OD, ORWH, OCPL
Other Participants: HHS-IHS, NIH-OD-EDI
Trans-NIH Behavioral and Social Sciences Research (BSSR) Coordinating Committee (BSSR CC)
This Coordinating Committee was established to enhance information exchange, communication, integration, and coordination of behavioral and social sciences research/training activities at the NIH. The BSSR Coordinating Committee works closely with the NIH Office of Behavioral and Social Sciences Research (OBSSR).
Trans-NIH Bioethics Committee
This committee was established to contribute directly to NIH’s policy development and decision-making process by serving as a forum for discussion and analysis on a range of issues related to the conduct and oversight of NIH-funded clinical research.
Trans-NIH BioMedical Informatics Coordinating Committee (BMIC)
BMIC was established to improve communication and coordination of issues related to clinical and bio-informatics at NIH and with other relevant entities. The committee provides a forum for sharing information about NIH informatics programs and initiatives, including those related to IT standards development. The Committee also develops resources to coordinate and advance NIH-wide objectives related to biomedical informatics, including data sharing policies and common data elements.
NIH Participants: NLM, CC, CIT, CSR, FIC, NCATS , NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, All NIH ICs, OD
Trans-NIH Chronic Inflammation Interest Group (CIIG)/Organizing Committee for a Trans-NIH Workshop
Chronic inflammation is known to be associated with the development of several diseases. The ability to detect, monitor and remediate such conditions can offer opportunities for early intervention and effective treatment. The National Cancer Institute (NCI) initiated an interest group of program staff from several NIH Institutes to take a comprehensive look at the status of research in this area. The group decided to convene a workshop to gather information on current status of research and technical capabilities across different disease and to generate recommendations derived from the cross-disciplinary discussion, which can be used for possible trans-NIH initiatives and Common Fund proposals.
Trans-NIH Community Engagement Interest Group
The Trans-NIH Community Engagement Interest Group began in May 2016 to facilitate cross-NIH Institute and Center coordination and discussion regarding engagement activities happening with various external communities. The interest group, which meets quarterly, focuses on: 1) supporting NIH outreach projects and publications; 2) cataloging what Institutes, Offices and Centers are doing with regards to community engagement; and 3) discussing community engagement evaluation methods and new engagement models.
Trans-NIH Coordinating Committee on HIV and Aging
This committee was established to promote intra-agency collaboration in fostering research on HIV and aging; to develop approaches to address novel research opportunities and existing gaps; to facilitate the coordination and funding of HIV and Aging research; and to identify issues and activities that should be brought before NIH advisory groups.
Trans-NIH Coordinating Committee on Research on Women's Health (CCRWH)
The purpose of the CCRWH is to assist the Director of the Office of Research on Women's Health in identifying the needs in conducting research on women's health; identifying needs regarding the coordination of research activities, including intramural and extramural multidisciplinary activities; and encouraging the Institutes and Centers to conduct and support this area of research, including clinical trials. The CCRWH serves as the major liaison with the NIH Institutes and Centers for communication and data exchange for trans-NIH focus on women's health research including setting research priorities, strategic planning, and development of collaborative research protocols or funding; career development programs; interdisciplinary collaborations; implementation of policies and programs to address the inclusion of women in clinical studies; and implementation of research on sex differences.
Trans-NIH Environmental Influences on Child Health Outcomes (ECHO) Working Group
Early in 2015, NIH created a working group to develop a plan to address research at the intersection of pediatric and environmental health. This working group, composed of representatives from 16 Institutes, Centers, and Offices within the NIH Office of the Director, is led by NIH's Principal Deputy Director and the Associate Director for Research on Women's Health. To gather feedback from the community on the direction of the plan, the working group coordinated numerous outreach activities. The working group will continue to provide scientific expertise to the ECHO Program Director and Program Office. The working group also will regularly advise the ECHO Program Director on the management and coordination of the program.
Trans-NIH Etiology of Health Disparities Working Group
This group is working to identify priority scientific questions, gaps, and opportunities to advance the science needed for the etiology of health disparities. Through conducting state-of the art scientific review and planning an etiology workshop for May 2016, the committee developed recommendations in four areas: social determinants, biological and environmental mechanisms, life course, and health services research.
Trans-NIH Fragile X Research Group
This group coordinates and monitors activities to implement high-priority research objectives described in the NIH Research Plan for Fragile X Syndrome and Associated Disorders. The group is composed of scientific experts across NIH. Group recommendations are designed for use by the NIH and research communities and to be shared with other federal agencies to facilitate coordinated research activities that will lead to timely detection, diagnosis, treatment, and prevention of the targeted disorders.
Trans-NIH Genetics/Genomics Coordinating Committee for HIV/AIDS Research
This committee was established to promote intra-agency collaboration in the conduct and funding of HIV/AIDS genetics research and related activities, as appropriate; to identify and develop approaches to address research opportunities and gaps; and to identify issues and activities that should be brought before NIH advisory groups.
Trans-NIH Genomic Data Submission and Management Taskforce
The Genomic Data Submission and Managemnet Taskforce will work within the Scientific Data Council structure to provide a forum to share experiences and develop common approaches across ICs to ensure that NIH policy implementation and oversight of the Genomic Data Sharing Policy is consistent, transparent, and efficient.
Trans-NIH Global Health Research Working Group (GHRWG)
The GHRWG was established to enhance cooperative program development, problem solving, and decision-making among participating NIH Institutes and Centers that support international research activities. The Working Group advises and assists the NIH Director and the Institute and Center Directors on policies, administrative issues, and scientific opportunities related to international research. The Working Group also assists the Institutes and Centers with planning and conducting international programs and activities, both independently and in coordination with other NIH entities.
Trans-NIH Liver Cancer Working Group
The charge of this working group is to develop an integrated NIH-wide plan for research in liver cancer that addresses basic, behavioral, translational, and clinical aspects of liver cancer aimed at the prevention and cure of the disease.
Established in 2012, the Trans-NIH Microbiome Working Group (TMWG) is a working group chaired by Human Microbiome Project staff and comprised of extramural staff from 19 Institutes and Centers. The TMWG meets monthly, serving as a forum for staff to plan workshops, discuss important meetings, develop Funding Opportunity Announcements, and discuss other activities relevant to NIH microbiome research support. Products of this working group include:
* Annual NIH-portfolio analysis of microbiome research support.
*Two Funding Opportunity Announcements on microbiome research which was signed on to by 10 Institutes and Centers, and a two-year pilot with Center for Scientific Review on a Microbiome Special Emphasis Panel.
*Contributions to the Office of Science and Technology Policy's 2015 Fast Track Action Committee Mapping the Microbiome (FTAC-MM) microbiome research portfolio analysis.
*In-depth NIH-wide portfolio analysis of extramural microbiome research over FY12-16 for an invited research paper for Cell Host and Microbe.
*The TMWG is also organizing an NIH-wide microbiome workshop August 16-18, 2017 as part of a close out activity of the HMP program.
*A commentary published in an October 2014 issue of Cell titled "Advancing the Microbiome Research Community" calls for support of interdisciplinary research, analytical rigor, standardization, and policy development to advance this rapidly developing field.
*NIH co-sponsored the 2nd HIV Microbiome workshop in November 17-18, 2016. This workshop further emphasized the need for additional research to understand the association between the host microbiome and HIV transmission risk and disease progression, including its effect on host immune responses.
Trans-NIH Minority Health and Health Disparities Reporting Working Group
This working group examines how NIH can reliably identify and prepare informative reports on minority health and health disparities scientific research, career development/training, and related activities as well as ascertain how to provide these data separately and/or synergistically. The group also examines the purpose of and current procedures used for minority health and health disparities reporting at NIH and determining whether improvements can be made.
Trans-NIH Mitochondrial Disorders Working Group (MiDi)
The MiDi encourages and facilitates basic mechanistic research on the mitochondria with the goal of nucleating trans-NIH communication about mitochondrial biology. It also seeks to facilitate clinical research into primary mitochondrial disorders and into disorders and health in which mitochondrial function and dysfunction play an important role. This group additionally works to leverage resources and improve therapies. Subgroups form on an ad hoc basis in order to develop specific initiatives.
Trans-NIH Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) Working Group
The goals of the working group are to: advance research on the cause, prevention, diagnosis, pathophysiology and treatment of ME/CFS; encourage biomedical researchers and organizations to study ME/CFS; and to communicate research information among and between NIH Institutes and Centers.
Trans-NIH Neurofibromatosis Working Group
This group brings together NIH staff working in programs relevant to the biology and treatment of neurofibromatosis with patient advocacy groups and other federal agencies with programs in the field of research. The goal of the group is to share advances in understanding disease pathology and treatment strategies and to identify opportunities to support activities that will further advance the fight against this disease.
Trans-NIH Plan for HIV-Related Research Coordinating Committees
Each scientific area of the strategic plan is developed by Coordinating Committees comprised of representatives from the NIH Institutes and Centers and scientific experts from other agencies, including the Centers for Disease Control and Prevention (CDC), the Health Resources and Services Administration (HRSA), Veterans Affairs, U.S. Agency for International Development (USAID), Department of Defense (DoD), and the President's Emergency Plan for AIDS Relief (PEPFAR). These committees assist in developing the annual Trans-NIH Plan for HIV-Related Research to ensure that the AIDS research budget funds the highest priority HIV/AIDS research. The plan 1) frames the development of the NIH AIDS research budget; 2) determines the use of NIH AIDS-designated dollars; 3) tracks and monitors HIV/AIDS research expenditures; and 4) informs the public, the scientific community, Congress, and the AIDS-affected communities about the NIH HIV/AIDS research agenda. The Plan also shapes the NIH investment in HIV/AIDS research.
NIH Participants: OAR, CSR, FIC, NCATS , NCCIH, NCI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NICHD, NIDA, NIDCR, NIDDK, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, OD, ORWH
Other Participants: USAID, PEPFAR, DoD, VA
Trans-NIH Proteostasis Scientific Interest Group (SIG)
The Proteostasis SIG provides a forum to facilitate interaction, communication, and collaboration among intramural and extramural researchers working on different areas of the Proteostasis Network. The goal of the SIG is to develop and promote research initiatives on proteostasis and its relevance to human health and disease.
Trans-NIH Rare Diseases Working Group
The charge of this group is to develop an integrated NIH-wide plan for research in rare diseases that addresses basic, translational, and clinical aspects aimed at the prevention and cure of rare diseases.
Trans-NIH Rehabilitation Research Coordinating Committee
The Trans-NIH Rehabilitation Research Coordinating Committee works together to advance rehabilitation research at the NIH. This committee's efforts aim to increase scientific knowledge to improve the quality of life for individuals with physical disabilities across the lifespan.
Trans-NIH Sarcoidosis Working Group
This group was established to share and coordinate information on sarcoidosis research and to develop activities that may be jointly sponsored, including workshops and program announcements to highlight opportunities for research and collaborative projects. The group holds annual meetings that focus on exchange of information and discussion of future opportunities in sarcoidosis research.
Trans-NIH Scientific Interest Group: Breastfeeding and Human Lactation Research
In January 2011, the U.S. Surgeon General released a Call to Action to Support Breastfeeding, by forming a federal steering committee representing many Department of Health and Human Services entities, including the National Institute of Child Health and Human Development (NICHD). The document called for increased research support for topics related to breastfeeding. The Breastfeeding and Human Lactation Research Scientific Interest Group was established to address issues raised in the Surgeon General's Call to Action. This interest group is composed of a diverse group of scientists within the NIH community who meet to discuss research gaps and needed studies related to breastfeeding.
Trans-NIH Scientific Research Interest Working Group on Biomarkers in Pediatric Therapeutics
A scientific research interest group to exchange information, coordinate efforts, and develop initiatives to discover and use biomarkers in research on pediatric therapeutics.
Trans-NIH Sex as a Biological Variable Working Group
The mission of this working group is to formulate approaches to encourage researchers to consider sex as a biological variable in preclinical research. Sex is a critical biological determinant to consider when trying to understand the underlying factors that fundamentally shape human health. It is a critical element to consider when designing preclinical research that informs human studies. NIH requires a deliberate approach in considering the influence of sex differences in research with vertebrate animals and humans. This transformation of the way science is conducted will better inform clinical research design - with the ultimate goal of improving the health of all women and men in the United States and globally. The working group has considered placement, criteria, and language of sex as a biological variable in grant applications; the group's recommendations were ultimately adopted by NIH for incorporation into application instructions and review criteria. The working group also collaborated with the NIH Working Group on Rigor and Transparency to develop a streamlined approach to enhance the rigor and transparency of science. The working group also developed and released a Request for Information, which asked the public to comment on the general idea of the policy, scientific areas where this would not be relevant, and barriers to implementation.
Trans-NIH Sleep Research Coordinating Committee
The National Center on Sleep Disorders Research, of the National Heart, Lung, and Blood, Institute (NHLBI), leads a forum for program officers in participating Institutes and Centers for the discussion of sleep and circadian research and potential opportunities for programmatic coordination. The scope of discussion includes research, training, health information dissemination, and other activities with respect to sleep disorders, including biological and circadian rhythm research, basic understanding of sleep, chronobiology, and other sleep related research. The committee provides a point of contact and coordination for other federal agencies and grant applicants. Members also participate in annual meetings of the Sleep Disorders Research Advisory Board and the development of an NIH Sleep Research Plan.
Trans-NIH Small Vessel Biology and Disease Working Group
The mission of this working group is to share existent knowledge and resources in the diverse research areas of small blood vessels in the brain, heart, lung, kidney, eye, and other organs, that falls under the purview of different NIH institutes, identify common challenges and gaps, and foster collaborative research on the normal function and malfunction of small blood vessels thought out the body. The working group recently organized a well-attended interdisciplinary symposium with topics that included basic biology and natural history of small vessels in health and disease, vascular dynamics, vessel-cellular interactions, research tools and innovation.
The Trans-NIH SBDWG brings together extramural program officials from NIH components whose missions include research into structural birth defects, with the ultimate goal of facilitating advances in our understanding of the etiology, mechanisms, epidemiology, prevention, and treatment of structural birth defects. The Working Group, coordinated by the National Institute of Child Health and Human Development (NICHD) through the Developmental Biology and Structural Variations Branch, aims to:
* Leverage existing scientific resources by enhancing communication between representatives of networks, consortia, and groups.
* Explore collaborations and activities that will advance research efforts through a coordinated effort.
* Optimize investments in research to maximize the impact of future funding.
* Liaise with other federal agencies (e.g., Centers for Disease Control and Prevention), organizations (e.g., March of Dimes), and societies (e.g., Teratology Society, Society for Developmental Biology) with an interest in birth defects research.
Trans-NIH Structural Birth Defects Working Group (SBDWG)
The Trans-NIH SBDWG brings together extramural program officials from NIH components whose missions include research on structural birth defects, with the goal of facilitating advances in our understanding of the etiology, mechanisms, epidemiology, prevention, and treatment of structural birth defects. The Working Group, coordinated by the National Institute of Child Health and Human Development (NICHD) aims to:
* Leverage existing scientific resources by enhancing communication between representatives of networks, consortia, and groups.
* Explore collaborations and activities that will advance research efforts through a coordinated effort.
* Optimize investments in research to maximize the impact of future funding.
* Liaise with other federal agencies (e.g., Centers for Disease Control and Prevention (CDC)), organizations (e.g., March of Dimes), and societies (e.g., Teratology Society, Society for Developmental Biology) with an interest in birth defects research.
Trans-NIH Training Advisory Committee (TAC )
The TAC advises the Chair of the Extramural Program Management Committee on issues related to extramural research training and career development programs and also provides a trans-NIH forum to identify and discuss issues related to these programs. Appropriate matters for TAC consideration will encompass a broad range of activities pertinent to programmatic aspects, review, grants management, and evaluation of training grants, fellowships, career development awards, education grants, and other related programs. In addition, TAC will consider the relationship of NIH extramural human resource development programs to the broader needs of the nation for biomedical, behavioral, and clinical research personnel. TAC also oversees the activities of the Division of Loan Repayment within the Office of Extramural Programs, including the Ruth L. Kirschstein National Research Service Award payback service center. Loan repayment program oversight is through a Policy Advisory Committee that is chaired by a TAC member designated by the Director of the Office of Extramural Programs. TAC has four subcommittees that include policy, diversity, evaluation, and workforce.
Trans-NIH Transgenerational Working Group
This working group was organized to promote trans-NIH collaboration in the area of transgenerational or intergenerational phenotypic inheritance with particular emphasis on promoting reproducibility and validation, as well as exploring mechanisms of phenotypic transmission. The working group will plan to convene a workshop focused on the state of the science of transgenerational inheritance, as well as plan to develop joint funding opportunity announcements.
Trans-NIH Tuberous Sclerosis Complex (TSC) Working Group
This group brings together NIH staff working in programs relevant to the biology and treatment of TSC with patient advocacy groups (e.g., TS Alliance) and other federal agencies with programs in TSC. The goal of the group is to share advances in understanding disease pathology and treatment strategies, as well as to identify opportunities to support activities that will lead to further research progress.
Trans-NIH Web Material Transfer Agreement Project
This project is focused on the development of an NIH-wide Web-based workflow management and database system to facilitate the rapid location of biological materials that can be shared from NIH laboratories and allow for near-instantaneous material transfer agreement turnaround time. The system also will provide novel metrics related to materials and investigators’ transfer patterns.
Trans-NIH Women’s Health Research Group
This research group is organized to support and encourage research on women's health issues at the basic, translational, and clinical levels to include the biology and disease status of different organ systems. The group organizes a monthly symposium series and a mentoring program for fellows supported to perform research studies focusing on women's health diseases.
Trans-NIH Working Group on Climate Change and Health
The Trans-NIH Working Group on Climate Change and Health is a cooperative effort focused on the current and future role of the NIH Institutes and Centers in climate change-related biomedical research. The National Institute of Environmental Health Sciences (NIEHS) co-chairs this group with the Fogarty International Center (FIC). NIH supports a wide range of research projects that are relevant to the health effects of climate change. These projects represent an ongoing platform from which NIH can begin to evolve a coherent research strategy including the identification of gaps and priorities for future investments. Activities that support the development of this strategy include research portfolio analyses, literature surveys, interagency discussions, stakeholder engagement, and workshops and conferences on climate change and global health.
Trans-NIH Working Group on Clinical Applications of Genomics
This working group is identifying ongoing efforts in genomic medicine implementation NIH-wide and opportunities for increased synergy and efficiency. It also is identifying leaders across participating Institutes and Centers who take responsibility for the growing opportunities related to implementing genomics in clinical care and representing the NIH as a whole in these efforts.
Trans-NIH Working Group on Coding Minority Health and Health Disparities
The Trans-NIH Working Group on Coding Minority Health and Health Disparities is working to create standardized coding criteria that distinguish minority health and health disparities research.
Trans-NIH Working Group on Defining Minority Health and Health Disparities
The Trans-NIH Working Group on Defining Minority Health and Health Disparities is developing a definition of the concepts of minority health and health disparities separately for NIH, including indicators to differentiate between the two areas of research.
Trans-NIH Working Group on Household Air Pollution
The Trans-NIH Working Group on Household Air Pollution aims to integrate and accelerate NIH-sponsored and -administered research in this field. The topical areas of principal concern are: developing a robust exposure response relationship of particulate matter and other pollutants to childhood pneumonia, low birth weight heart disease, lung cancer, stroke, eye disorders, and other conditions, as well as advancing our understanding of the systemic and behavioral barriers to adoption and use of the technology in low income settings around the world.
Trans-NIH Working Group on Intervention Science
The Trans-NIH Working Group on Intervention Science is examining the state-of-the science and promising interventions addressing health disparities with a focus on population level interventions. The group seeks to propose strategies to establish an evidence base for effective health disparities interventions and describe optimal methods for intervention delivery and evaluation in health disparity populations.
Trans-NIH Working Group on Intimate Partner Violence and HIV
This Working Group was established to ensure that NIH has a coordinated, multidisciplinary research response to address the intersection of HIV and intimate partner violence.
Trans-NIH Xenopus Working Group
The mission of the Trans-NIH Xenopus Initiative, established in 1999, is to create critical community-wide resources for Xenopus models that aid in the understanding of embryonic development, organogenesis, oncogenesis, and cell biological processes. This initiative includes genomic and genetic resources, scientific meetings, and research program announcements.
Trans-NIH Zebrafish Coordinating Committee
The NIH established the Trans-NIH Zebrafish Coordinating Committee in 1997 in response to the scientific community's recommendation to promote the use of zebrafish as a model organism for the study of vertebrate development and disease. A website was developed to provide a central information resource, focusing on major NIH-organized zebrafish meetings; funding opportunities for zebrafish genomics and genetic resources; major resources generated from grants funded in response to trans-NIH zebrafish initiatives training courses and scientific meetings related to the zebrafish initiatives; and selected reports and publications.
Translational Research Interest Group
The purpose of this group is to bring physicians and scientists from various disciplines together to discuss (1) efficient ways to accelerate the application of biomedical research discoveries to better help patients, and (2) the translation of clinical research observations into the development of improved preclinical disease models. This intramural scientific interest group coordinates seminars and workshops to help bridge the gap between laboratory research and clinical applications.
Treating for Two Interagency Working Group (Medications in Pregnancy)
This committee provides information to women and their healthcare providers about safer medication use in pregnancy, and aims to prevent birth defects and improve treatment of common conditions during pregnancy.
U. S. Government Interagency Working Group on Nanotechnology Environmental, and Health Implications (NEHI), of the Nanoscale Science, Engineering, and Technology Subcommittee (NSET) of the National Science and Technology Council (NSTC)
The Nanoscale Science, Engineering, and Technology (NSET) Subcommittee and Nanotechnology Environmental, and Health Implications (NEHI) Working Group provide leadership in establishing the national nanotechnology environmental, health, and safety research agenda and in communicating data and information related to environmental and health aspects of nanotechnology between National Nanotechnology Initiative (NNI) agencies and with the public. NNI activities support the development of new tools and methods required for the research that will enable risk analysis and assist in regulatory decision-making. NNI agencies engage and interact with regional, state, and local groups, educational institutions, industry-supported groups, and non-governmental organizations to enhance the impact and value of NNI efforts and to provide a collaborative approach.
U.S. Department of Agriculture (USDA)-NIH-Industry Nutrition Behavior Working Group
This Working Group works to identify areas that can be pursued in academic-government-industry partnerships, including identifying barriers to long-term adherence to healthy diets, how altering one aspect of dietary patterns may affect other aspects, how enhancing flavor may increase consumption of healthier diets, and how healthier food choices could be effectively translated to a variety of environments (schools and colleges, families, workplaces) so that consumers could more easily adopt and maintain healthy diets.
U.S.-Brazil Working Group on Biomedical Collaborative Research
This bilateral program between the United States and Brazil was established in 2014 with the signing of a Letter of Intent between the NIH and the Brazil Ministry of Health, and the Brazil Ministry of Science, Technology, and Innovation. The program aims to develop a coordinated program that will foster collaborative health research focused on areas of mutual interest and shared scientific priority. Initial collaborations between U.S. and Brazilian scientists focused on areas of cancer, allergy, immunology, and/or infectious diseases (including HIV/AIDS and its co-morbidities).
U.S.-China Program for Biomedical Collaborative Research Working Group
The purpose of the U.S.-China Program for Biomedical Collaborative Research Working Group is to stimulate collaborative basic, translational, and applied research between U.S. and Chinese researchers in the areas of allergy, immunology, and infectious diseases including HIV/AIDS and its co-morbidities and co-infections, cancer, mental health, Parkinson's disease, and stroke.
U.S.-China Program for Collaborative Research Toward a Cure for HIV
The bilateral program for research collaboration between the United States and China was established in October 2010 with the signing of a Memorandum of Understanding between the NIH Director and the President of the National Natural Science Foundation of China, and was renewed in October 2015. An Implementing Arrangement to establish a joint program for collaborative research toward a cure for HIV was subsequently signed in August 2013 in the context of the Memorandum. The purpose of this collaboration is to foster, stimulate, and/or expand basic, translational, behavioral, and applied research that will advance research toward a cure for HIV.
U.S.-India Joint Working Group on Prevention of Sexually Transmitted Diseases (STDs) and HIV/AIDS
This bilateral program between the United States and India was established in 2006 with the signing of a Joint Statement on the Prevention of STDs and HIV. The program aims to facilitate collaborations on research and training between the United States and India that involve trans-NIH HIV/AIDS research efforts and the participation of multiple NIH Institutes. An exchange of letters was signed in 2015 by the Secretary of the Indian Department of Health Research and the OAR Director to extend the bilateral program beyond 2015.
U.S.-Russia Collaboration on Research Related to HIV/AIDS
This bilateral program between the United States and Russia was established in March 2011 with the signing of a Memorandum of Understanding between NIH and the Russian Foundation for Basic Research, and renewed in April, 2015. The program was established to foster and facilitate international collaborative research and research training on HIV/AIDS and the exchange of scientific information between U.S. and Russian researchers in several scientific focus areas corresponding to the NIH AIDS priorities including basic research, genomics, reearch toward a cure, and other HIV-associated comorbidities such as cancer.
US Domestic Cohort Program: Multicenter AIDS Cohort Study, Women's Interagency HIV Study
The U.S. domestic HIV observational cohorts are overseen by a multi-Institute team of program officers. Semi-annual meetings are held to review progress and evaluate future directions. The domestic cohorts are charged with understanding the population-level effectiveness of HIV care from research on HIV risk, to transmission, uptake of care, success of therapies, and the interaction of HIV infection, contextual factors, co-morbidities and aging among individuals with and at risk of HIV.
Vaccines for Cancer Prevention Working Group
This working group activity examines potential areas of overlap between the National Cancer Institute (NCI) and the National Institute of Allergy and Infectious Diseases (NIAID). The goal is to identify vaccine studies of infectious agents that can be integrated to include preventative vaccine strategies for cancer. In FY 2012, the NCI Division of Cancer Prevention established a working group to examine research opportunities in immunoprevention and develop future activities.
Vertebrate Animal Section Working Group
This group updates the vertebrate animal section of grant applications and contract proposals to reduce burden to applicants, removes redundancy with Institutional Animal Care and Use Committee review requirements, and addresses current issues related to research with animals. The working group completed its update to grant application instructions and contract proposals effective January 2016.
Virology Interest Group
The Virology Interest Group includes researchers at NIH and in the local area who are interested in virology. The group organizes activities designed to promote interactions and exchange of information. The Virology Interest Group sponsors the Norman P. Salzman Memorial Award and Symposium in November of each year. The Symposium is held in conjunction with the presentation of the Annual Norman P. Salzman Memorial Award that recognizes outstanding accomplishments by a post-doctoral fellow or research trainee at NIH working in the field of virology.
Women-Owned, and Socially and Economically Disadvantaged Businesses Working Group
This Working Group explores the participation of women and minority participation in the SBIR program at NIH and the Centers for Disease Control and Prevention.
Working Group on Hydrocephalus and Hindbrain Malformations
The group shares information about ongoing research activities and identifies research needs and opportunities for collaboration, both across NIH institutes and with non-governmental organizations that support hydrocephalus and hindbrain malformations research. The focus is on basic and clinical research in midbrain/hindbrain malformations and hydrocephalus.
Working Group on the NIH Project to Establish Biomedical Beamlines at NSLS-II
This working group was established to coordinate activities related to biomedical research at the new Department of Energy user facility for high energy x-rays at National Synchrotron Light Source-II (NSLS-II). The group monitors and plans for instrumentation requirements for x-ray diffraction and x-ray scattering applications at NSLS‑II.